Dr. David Knight

Contact

Associate Professor, Psychology

Other information

Other information:
David KnightContact Information:

Email: knightdc@uab.edu
Office Phone: (205) 996 6344

Fax: (205) 975 6110

Education:

B.S., 1994, Truman State University, Psychology
M.S., 1999 University of Wisconsin-Milwaukee, Psychology Internship,
2001-2002, West Virginia University School of Medicine, Neuropsychology
Ph.D., 2002, University of Wisconsin-Milwaukee, Psychology
Postdoctoral Fellowship, 2002-2007, National Institute of Mental Health

Curriculum Vitae

Research Program:

Dr. Knight’s laboratory is focused on better understanding the neural substrates of human learning, memory, and emotion using magnetic resonance imaging (MRI) techniques that include functional MRI, diffusion tensor imaging, and magnetic resonance spectroscopy. Behavioral and MRI studies from the lab investigate questions that are important for understanding healthy, as well as dysfunctional, emotion processes. For example, recent work from the Knight lab has investigated the neural circuitry that supports emotion regulation processes. Disruption of these processes appears to play an important role in the emotional dysfunction associated with mood and anxiety disorders. Studies from the Knight lab will help determine neural mechanisms that mediate susceptibility/resilience to stress, and offer insights into the development of emotion-related disorders.



Representative Publications:

Knight, D. C. Waters, N. S., & Bandettini, P. A. (2010).Learning-related diminution of unconditioned SCR and fMRI signal responses. NeuroImage, 49, 843-848.


Knight, D. C., Nguyen, H. T., & Bandettini, P. A. (2003). Expression of conditional fear with and without awareness. Proceedings of the National Academy of Sciences, 100 (25), 15280-15283.

Knight, D. C., Cheng, D. T., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2004). Neural substrates mediating human delay and trace fear conditioning. Journal of Neuroscience, 24 (1), 218-228.

Knight, D. C., Nguyen, H. T., & Bandettini, P. A. (2005). The role of the human amygdala in the production of conditioned fear responses. NeuroImage, 26, 1193-1200.

Knight, D. C. Waters, N. S., & Bandettini, P. A. (2009). Neural substrates of explicit and implicit fear memory. NeuroImage, 45, 208-214.

Wood, K. H., Ver Hoef, L. W., & Knight, D. C. (2012). Neural mechanisms underlying the conditioned diminution of the unconditioned fear response. NeuroImage, 60 (1), 787-799.

Haritha, A. T., Wood, K. H., Ver Hoef, L. W. & Knight, D. C. (2013). Human Trace Fear Conditioning: Right Lateralized Cortical Activity Supports Trace Interval Processes. Cognitive, Affective, and Behavioral Neuroscience, 13 (2), 225-237.

Reagh, Z. M. & Knight, D. C. (2013). Negative, but not positive emotional images modulate the startle response independent of conscious awareness. Emotion, 13(4), 782-791.

Wood, K. H., Ver Hoef, L. W., & Knight, D. C. (In Press). The Amygdala Mediates the Emotional Modulation of the Startle Response. Emotion.