Dr. Mary M. Boggiano

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Associate Professor, Psychology

Other information

Other information:
MAry BoggianoContact Information:
Email: boggiano@uab.edu
Office Phone: (205) 934 2408 
Fax: (205) 975 6110

Education:
PhD, 1998, University of Texas at El Paso, Psychology
Post-Doc, 2000, University of Cincinnati Medical College, Psychiatry

Research Program: 
Past areas of research included the development of animal models of binge-eating (e.g., Stress + Dieting model) and models showing the independence of binge-eating and obesity (e.g., Binge-eating Prone vs. Resistant or “BEP/BER” model). Drug, HPLC, and RIA studies implicated sensitization of mu-opioid receptors, dysregulation of mesolimibic monoaminerelease, and increased cortisol as mechanisms behind binge-eating.   Other systems studied are the role of central PYY and the melanocortin system in eating behavior. Novel behavioral methods included use or increasing levels of foot shock to test the motivation of rats for palatable food and a Pavlovian model of conditioned overeating. Dr. Boggiano’s animal models of binge-eating and obesity are being used in academic and industry labs to gain a better understanding of the physiology of binge-eating disorders and obesity and to test the efficacy of new drugs for these conditions. Other research involved the use of Ansel Key’s famous WWII Minnesota Starvation Experiment surveys in modern-day individuals to assess the role of dieting in binge-eating and chaotic eating behaviors such as food concocting.

Current research is focused solely on human subjects and includes the development, validation, and testing of a novel scale to assess motives behind eating highly palatable food (the Palatable Eating Motives Scale or “PEMS”) in adolescents, teens, college students, and weight-loss seeking adults. The PEMS should personalize and hence improve treatments for obesity and binge-eating. Current research also involves testing the efficacy of transcranial direct current stimulation (tDCS) to reduce food cravings and binge-eating traits in humans.   Future studies will aim to identify the neural substrates of tasty-food intake for distinct motives and the effect of tDCS on eating behavior. A second aim will involve designing intervention studies using the PEMS and tDCS to treat obesity and binge eating.

BoggianoResearchPhoto2014

Representative Publications (Hagan is former name):

Burgess, E. E., Bulent, T., Lokken, K. L., Morse, T., & Boggiano, M. M. (2014). Profiling motives behind hedonic eating: Preliminary validation of the Palatable Eating Motives Scale. Appetite, 72: 66-72.

Boggiano,M. M., Turan, B., Maldonado, C. R., Oswald, K. D., Shuman, E. J. (2012). Secretive food concocting in binge-eating: Test of a famine hypothesis. International Journal of Eating Disorders, 46: 212–225.

Corwin, R. Avena, N. M. & Boggiano, M. M. (2011). Feeding and reward: perspectives from three rat models of binge eating. Physiology & Behavior, 104: 87-97.

Oswald, K. D., Murdaugh, L. D., King, L. V. & Boggiano, M.M. (2010). Motivation for palatable food despite consequences in an animal model of binge-eating. International Journal of Eating Disorders, 44: 203-211.

Boggiano, M.M., Dorsey, J., Thomas, J. M., & Murdaugh, D. (2009). The Pavlovian power of palatable food: lessons for weight-loss adherence from a new rodent model of cue-induced overeating. International Journal of Obesity, 33:693-701.

McAllister, E. J., Dhurandhar, N. V., Keith, S., Aronne, L. J., Barger, J. , Baskin, M., Benca, R. M., Biggio, J., Boggiano, M.M., Eisenmann, J. C., Elobeid, M. , Fontaine, K., Gluckman, P., Hanlon, E. C., Katzmarzyk, P., Pietrobelli, A., Redden, D. T., Ruden, D. , Wang, C., Waterland, R., Wright, S., & Allison, D. B. (2009). Ten putative contributors to the obesity epidemic. Critical Reviews in Food Science and Nutrition, 49, 868-913.

Boggiano, M.M., Cavigelli, S. A., Dorsey, J. R., Pritchett-Kelley, C. E., Ragan, C.M., & Chandler-Laney, P. C. (2008). Effect of a cage divider permitting social stimuli on stress and food intake in rats. Physiology & Behavior, 95, 222-228.

Chandler-Laney, P.C., Castaneda, E., Artiga, A.I., Eldridge, A., Maddox, L., & Boggiano, M.M. (2007). History of caloric restriction induces neurochemical and behavioral changes in rats consistent with models of depression. Pharmacology, Biochemistry and Behavior, 87: 104–114.

Artiga, A. I., Viana, J. B., Maldonado, C.R., Chandler-Laney, P. C., Oswald, K. D. & Boggiano, M.M. (2007). Body composition and endocrine status of long-term stress-induced binge-eating rats. Physiology & Behavior, 91, 424-431.

Boggiano, M.M., Artiga, A. I., Pritchett, C. E., Chandler, P.C., Smith, M. L., & Eldridge, A. J. (2007). High intake of palatable food predicts binge-eating characteristics independent of susceptibility to obesity: An animal model of lean vs. obese binge eating and obesity with and without binge-eating. International Journal of Obesity, 31:1357-67.

Chandler, P.C., Castaneda, E., Viana, J.B., Oswald, K.D., Maldonado, C., & Boggiano, M.M., (2007). A history of human-like dieting alters serotonergic control of feeding and neurochemical balance in a rat model of binge-eating. International Journal of Eating Disorders, 40, 136-142.

Keith, S., Redden, D. T., Katzmarzyk, P., Boggiano, M.M., Hanlon, E. C., Benca, R.M., Ruden, D., Pietrobelli, A., Barger, J., Fontaine, K., Wang, C., Aronne, L., Wright, S., Baskin, M., Dhurandhar, N., Lijoi , M.C., Grilo, C., Deluca, M., Westfall, A. O. & Allison, D. B. (2006). Putative contributors to the secular increase in obesity: Exploring the roads less traveled. International Journal of Obesity, 30, 1585-94.

Boggiano, M.M., Chandler, P. C., Viana, J. B., Oswald, K. D., Maldonado, C. R., & Wauford, P. K. (2005). Combined dieting and stress evoke exaggerated responses to opioids in binge-eating rats. Behavioral Neuroscience, 119, 1207-1214.

Chandler, P. C., Viana, J. B., Oswald, K. D., Wauford, P. K., & Boggiano, M.M., (2005). Feeding response to melanocortin agonist predicts preference for and obesity from a high-fat diet. Physiology & Behavior, 85, 221-230.

Tschop, M., Castaneda, T. R., Joost, H. G., Thone-Reineke, C., Ortmann, S., Klaus, S., Hagan, M. M., Chandler, P. C., Oswald, K. D., Benoit, S. C., Seeley, R. J., Kinzig, K.P., Moran, T. H., Beck-sickinger, A.G., Koglin, N., Rodgers, R.J., Blundell, J.E., Ishii, Y., Beattie, A.H., Holch, P., Allison, D. B., Raun, K., Madsen, K., Wulff, B.S., Stidsen, C.E., Birringer, M., Kreuzer, O. J., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Deng, X.Y., Withcomb, D.C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Craney, S., Flora, D., Smiley, D., Heiman, M. L. (2004). Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature, 430 (6996): pg. 1-2 following 165.

Placidi, R. J., Chandler, P. C., Oswald, K. D., Maldonado, C., Wauford, P. K. & Boggiano, M. M. Stress and hunger alter the anorectic efficacy of fluoxetine on the binge-eating of rats with a history of caloric restriction, International Journal of Eating Disorders, 36, 1-14.

Chandler, P. C., Oswald, K. D., Maldonado, C., Wauford, P. K., Placidi, R. J. & Hagan, M. M., (2004). Effect of cholecystokinin (CCK-8) on hyperphagia induced by a high-fat diet and melanocortin antagonism, Peptides, 25, 299-306.

Hagan, M. M., Chandler, P. C., Wauford, P. K., Rybak, R. J., & Oswald, K. D. (2003). The role of palatable food and hunger as trigger factors in an animal model of stress-induced binge-eating. International Journal of Eating Disorders, 34, 183-197.

Hagan, M. M., Shuman, E. S., Oswald, K. D., Corcoran, K. J., Profitt, J. H., Blackburn, K. Schwiebert, M. W., Chandler, P.C., Birbaum, C. (2002). Incidence of Chaotic Eating Behaviors in Binge-Eating Disorder: Contributing Factors. Behavioral Medicine, 28, 99-105.

Hagan, M. M., Wauford, P. K., Chandler, P. C., Jarrett, L. A., Rybak, R. J., & Blackburn, K. (2002). A new animal model of binge eating: key synergistic role of past caloric restriction and stress. Physiology & Behavior, 77, 45-54.

Hagan, M. M., Benoit, S. C., Rushing, P. A., Pritchard, L. M., Woods, S. C., & Seeley, R.J. (2001). Immediate and prolonged patterns of AgRP (83-132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites. Endocrinology, 142 (3), 1050-1056.

Hagan, M. M., Rushing, P. A., Benoit, S. C., Woods, S. C., & Seeley, R. J. (2001). Opioid receptor involvement in the effect of AgRP(83-132) on food intake and food selection. American Journal of Physiology, 280: R814-R821.

Hagan, M. M., Rushing, P.A., Pritchard, L. M. Schwartz, M. W., Strack, A., Vander Ploeg, L., Woods, S.C. & Seeley, R. J. (2000). Long-term orexigenic effects of agouti related peptide (83-132) involve mechanisms other than melanocortin receptor blockade. American Journal of Physiology ,279, R47-R52. Hagan, M. M., Whitworth, R. H., & Moss, D. E. (1999). Semistarvation-associated eating behaviors among college binge-eaters: A preliminary description and assessment scale. Behavioral Medicine, 25, 125-133.

Hagan, M. M., Havel, P. J., Seeley, R. J., Woods, S. C., Ekhator, N. N., Baker, D. G., Hill, K. K., Wortman, M. D., Miller, A. H., Gingerich, R. L., & Geracioti, T. D. (1999). Cerebrospinal fluid leptin measurements: Covariability with dopamine and cortisol in fasting humans. Journal of Clinical Endocrinology & Metabolism, 84, 3579-2558.

Hagan, M. M., Rushing, P. A., Schwartz, M. W., Yagaloff, K. A., Burn, P., Woods, S.C.,& Seeley, R. J. (1999). Role of CNS melanocortin system in response to overfeeding. Journal of Neuroscience, 19, 2362-2367.

Hagan, M. M., Castañeda, E., Fleming, S. M., Sumaya-Smith, I., Galloway, J., & Moss, D. E. (1998). Effect of peptide YY (PYY)-induced eating and drinking on the in vivo release of hippocampal acetylcholine (ACh), Brain Research, 805, 20-28.

Hagan, M. M., & Moss, D. E. (1997). Persistence of binge-eating patterns after a history of restriction with intermittent bouts of refeeding on palatable food in rats: Implications for bulimia nervosa. International Journal of Eating Disorders, 22, 411-420.

Hagan, M. M., & Moss, D. E. (1995). Effect of peptide YY (PYY) on food-associated conflict. Physiology & Behavior, 58, 731-735.

Hagan, M. M., & Moss, D. E. (1991). An animal model of bulimia nervosa: opioid sensitivity to fasting episodes. Pharmacology, Biochemistry & Behavior, 39, 421- 422.


Teaching Interests:

PY101 - Intro to Psychology; PY335 - Motivation & Emotion; PY455/791 - Psychology of Eating Disorders & Obesity; Lectures in graduate Behavioral Neuroscience courses

Teaching Awards: 

Professor of the Month Award - Alpha Omicron Pi (UAB), 2002 -Who’s Who Among America’s Teachers (Student Nominated), 2003 -Academic Keys Who's Who in Social Sciences Higher Education, 2004 -Selection to UAB -Master Teacher Program, 2005 -President’s Award for Excellence in Teaching (UAB School of Social & Behavioral Sciences), 2006 -Professor of the Month Award – Alpha Omicron Pi (UAB), 2007 -Professor of the Month Award – Alpha Omicron Pi (UAB), 2010

For Information on Eating Disorders: