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What Is Informatics?
Elliot J. Lefkowitz, PhD
Dr. Lefkowitz is a Professor in the Department of Microbiology. His research focuses on the genomics and evolution of microorganisms, especially viruses; the development and use of bioinformatics tools and techniques to support genomics research; and the provision of informatics support across the full spectrum of biomedical research. In addition to serving as Director of Informatics for the CCTS, he is also Director of Bioinformatics for the UAB Center for AIDS Research, and Director of Bioinformatics for the UAB Microbiome Facility.
Jonas S. Almeida, PhD
Dr. Almeida is Chair of the Data Working group of the Advisory Committee of the National Science Foundation Directorate for Biological Sciences. His computational research and tool development is focused on the integration of biomolecular and clinical data and the advancement of personalized medicine through the development of tools required to support the use of these data for patient care, including development of novel informatics algorithms and the corresponding software libraries to the development of novel integrative computational infrastructure, especially supporting the use of genomic data.
Eta S. Berner, EdD
Dr. Berner is a former member of the Board of Directors of the American Medical Informatics Association, the External Scientific Panel for NHGRI’s Emerge Network and the Technical Expert Panel for the AHRQ Clinical Decision Support Initiative.
She is responsible for the development and oversight of CCTS Informatics educational activities and works with others at UAB to oversee and develop policies concerning consent and governance issues surrounding the use of clinical data for research.
Geoff Gordon, MSEE
Mr. Gordon is an IT Director for the Health System Information Services division of UAB Health System, responsible for Web Development and the Enterprise Data Warehousing Iniative.
He has been working in clinical analytics for the past 3 years and has over 20 years of software development experience, 15 in healthcare.
James H. Willig, MD, MSPH
Dr. Willig is the Medical Informatics Director of the UAB 1917 AIDS Clinic, Co-Director of the UAB HIV-Research and Informatics Service Center, and Director of Clinical Informatics for the UAB Health System Information Services. He also serves as the physician lead for the Clinical Data Warehouse Research Working Group. His own research involves the development and use of informatics tools and methods to support patient care, especially for patients living with HIV.
Matthew Wyatt, MSHI
Mr. Wyatt provides operational management for all aspects of Informatics day-to-day activities. He is responsible for oversight of institutional collaborative projects including those related to clinical data warehousing, clinical data capture at the point of care, and clinical data extraction.
Senior System Analyst
Mr. Bobitt is a Senior System Analyst and Java developer. He is developing systems to extract data from i2b2 and VDW based Clinical Data Warehouses for cohort discovery and Java based software for direct database access of VDW systems and RESTful web interface access of i2b2 systems.
Chiquito J. Crasto, PhD
Dr. Crasto is an Assistant Professor in the Department of Genetics. He has extensive research experience in bioinformatics and computational biology. In addition, Dr. Crasto organizes the monthly Biomedical Informatics and Computational Biology Discussion Group. He is also involved in the development and oversight of educational programs focused on Bioinformatics and Computational Biology.
David K. Crossman, PhD
Dr. Crossman is an Instructor in the Department of Genetics. He directs the Bioinformatics Facility at the Heflin Center for Human Genetics and is responsible for the initial processing and analysis of Next-Gen Sequencing data obtained for Genomics’ Illumina sequencers. He provides CCTS investigators with expertise in microarray analysis, Next-Gen Sequencing analysis, mass spectrometry proteomics analysis, and Systems Biology pathway analysis.
Don Dempsey, MS
Mr. Dempsey is a web and Java developer who is responsible for the development of many of our web-based applications and databases. This includes working with clinical and translational researchers to create data capture forms and clinical, outcomes, and bioinformatics databases; assisting researchers with analysis and extraction of data from the Clinical Data Warehouse; developing new clinical and bioinformatics tools; and specific programming needed to develop the tools and systems supporting the needs of individual investigators.
Mr. Hendrickson provides expertise in data collection, integration, and reporting. This includes scientific database design, implementation, and support, as well as in web site design, web application development, and project management. He also supports a variety of bioinformatics-related services including Next-Gen Sequencing analysis, detection of sequence variants, and detection of gene regulatory motifs.
Ranjit Kumar, PhD
Dr. Kumar’s research has focused on whole genome transcriptome analysis of bacterial pathogens, which led to identification of numerous novel non-coding RNAs and proteins. He has also worked on host-pathogen protein-protein interactions by developing a non-redundant web based relational database that has advanced capabilities for host-pathogen interaction storage, retrieval, and data mining. He provides bioinformatics support and application development to investigators, especially focusing on the analysis of Next-Gen Sequencing data including microbiome and metagenomic analysis. He is responsible for the installation, maintenance, and support of all associated tools and data sources supporting microbiome analysis, and he has developed and is currently supporting the analytical pipeline used by the CCTS to support the analysis of data derived from human microbiome studies.
John Osborne, MS
Mr. Osborne works with clinical and translational researchers to create data capture forms and clinical, outcomes, and bioinformatics databases; assists researchers with analysis and extraction of data from the data warehouses; and works extensively with UAB investigators on the analysis of Next-Gen Sequencing data derived from patients enrolled in clinical research studies. He also develops new approaches and applications to support the extraction of clinical information from free-text records in order to store that information in structured database fields.
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The UAB CCTS is supported through the
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