Research & Scholarly Activities

The Department of Periodontology is actively engaged in clinical and translational research that truly focuses upon the UAB School of Dentistry’s core values: excellence, patient-centered, innovation, and unity of purpose. We aim to conduct research that meets the highest standards in a state-of-the-art facility to provide benefits to our patients and to expand the knowledge base in periodontology. Our research interests include periodontal-systemic connection, innovative regenerative technologies, endosseous dental implant innovations, epigenetics, and the periodontal microbiome.

Active studies include:

  • APART (Autoantibodies and Periodontal Health Assessment in Rheumatoid Arthritis)
  • OHMOM (Oral Health and Maternal Outcomes Measures) (NCT01549587)
  • Performance of Microtextured Implants (NCT0181417)
  • Performance of Growth Factor in Vertical Defects (NCT01728844)
  • Performance of Enamel Matrix Derivatives in Horizontal Bone Loss
  • A Prospective Study of Augmentation Techniques in Extraction Sites (NCT01836783)

Department Publications 2013-2014

Articles

  • Geisinger ML, Holmes CM, Vassilopoulos PJ, Geurs NC, Reddy MS. Is laser disinfection an effective adjunctive treatment to bone augmentation for periimplantitis? A Review of Current Evidence. Clin Adv Periodontics August 2013; doi/pdf/10.1902/cap.2013.130048
  • Geisinger ML, Robinson M, Kaur M, Gerlach RW, Griffin R, Geurs NC, Reddy MS. Individualized oral health education improves oral hygiene compliance and clinical outcomes in pregnant women with gingivitis. Journal of Oral Health and Hygiene 1(2): 1000111, 2013. (not supported by NIH).
  • Geisinger ML, Geurs NC, Bain JL, Kaur M, Vassilopoulos PJ, Cliver SP, Haugh JC, Reddy MS. Oral Health Education and Therapy Reduces Gingivitis During Pregnancy. J Clin Periodontol Oct 2013 doi:10.1111/jcpe.12188 [Epub ahead of print]. PMC Journal – In Process
  • Geisinger ML, Holmes CM, Geurs NC, Reddy MS. Does nonsurgical periodontal therapy in obese and overweight patients result in a change in body mass index (BMI)? A review of current evidence. Clin Adv Periodontics doi/pdf/10.1902/cap.2013.130063 (Epub Ahead of Print). October, 2013.
  • Geurs N, Ntounis A, Vassilopoulos P, Van der Velden U, Loos BG, Reddy M. Using growth factors in human extraction sockets: A histologic and histomorphometric evaluation of short-term healing. Int J Oral Maxillofac Implants. 29:485-496. Doi:10.11607/jomi.3408, 2014
  • Geisinger ML, Holmes CM, Geurs NC, Reddy MS. Does ridge preservation at the time of tooth extraction improve soft tissue volume and/or implant esthetics? A review of current evidence. Clin Adv Periodontics [Submitted, Under Review]
  • Geisinger ML, Abou-Arraj RV, Souccar NM, Holmes CM, Geurs NC. Decision Making in the Treatment of Patients with Malocclusion and Chronic Periodontitis: Scientific Evidence and Clinical Experience Clinical Adv Periodontics [Submitted, Under Review]
  • Abou Arraj RV, Majzoub ZAK, Holmes CM, Geisinger ML, Geurs NC. Healing time for final restorative therapy following surgical crown lengthening procedures: A review of related evidence. Clin Adv Periodontics April 2014; doi/pdf/10.1902/cap.2014.140014
  • Geisinger ML, Holmes CM, Vassilopoulos PJ, Geurs NC, Reddy MS. Is laser disinfection an effective adjunctive treatment to bone augmentation for periimplantitis? A review of current evidence. Clin Adv Periodontics August 2013 doi/pdf/10.1902/cap.2013.130048 [Epub ahead of print]. (not supported by NIH).
  • Reddy MS, Geurs NC, Geisinger ML, O'Neal SJ, Haigh SJ. A controlled, double-blind, parallel-arm clinical trial to evaluated the effectiveness of laser-ablated implant abutments for enhanced mucosal healing. J Periodontol [Accepted for publication]
  • Kaur M, Geisinger ML, Griffin RL, Vassilopoulos PJ, Reddy MS. The effect of an intensive oral hygiene regimen on pregnancy outcomes and gingival inflammation during pregnancy: Clinical and Laboratory analysis. J Periodontol [Submitted, under review]
  • Geisinger ML, Abou Arraj RV, Souccar NM, Holmes CM, Geurs NC. Decision making in the treatment of patients with malocclusion and chronic periodontitis: scientific evidence and clinical experience. Clin Adv Periodontics [Submitted, under reivew]
  • Geurs N, Ntounis A, Vassilopoulos P, Reddy M. Subjective assessement of bone quality of human extraction sockets after conversion with growth factors. [Submitted, under review]
  • Abou-Arraj RV, Souccar NM. Periodontal Treatment of Excessive Gingival Display. Semin Orthod 2013; 267-278.
  • Meouchy B, Abillamaa F, Maalouf EA, Mouchref-Hamasni F, Abou-Arraj R. Replacement of a missing maxillary central incisor with an Astra Tech® implant following a horizontal ridge augmentation using a symphyseal mandibular onlay graft: a case report. Journal of the Lebanese Dental Association 2013; 48(1):75-81.
  • Bain JL, Bonvallet PP, Abou-Arraj RV, Schupbach P, Reddy MS, Bellis SL. Enhancement of the regenerative potential of anorganic bone grafts utilizing a calcium binding domain to anchor osteoinductive peptides. [submitted]
  • Cardaropoli D, Gaveglio L, Abou-Arraj RV. Orthodontic Movement and Periodontal Bone Defects: Rationale, Timing and Clinical Implications. [submitted]

Abstracts

  • “Evidence Based Dentistry: Answering Clinical Questions", Keynote lecture, Lebanese Association for Dentofacial Research, Annual Meeting (IADR Lebanese Chapter), Beirut, Lebanon, December 14, 2013
  • Kaur M, Bain JL, Geisinger ML, Geurs NC, Reddy MS. Gingival inflammation reduction alters GCF cytokine levels in pregnancy gingivitis. AAP Research Symposium Poster Presentation, 2013
  • Garner E, Geurs NC, Geisinger ML. Periodontal inflamed surface area is correlated to Rheumatoid Arthritis symptoms. J Dent Res 93: 1269, 2014. AADR 2014 Poster Presentation.
  • Michalowicz BS, Hyman L, Hou W, Oates TW, Reddy MS, Katancik JA, Engebretson SP, and For The DPTT Study Team. Factors associated with periodontal treatment response in adults with diabetes. J Dent Res 93: 752, 2014.
  • Engebretson, S. Michalowicz, B., E.R. Seaquist, M. Reddy, C.E. Lewis, T. Oates, D. Tripathy, J. Katancik, P.R. Orlander, D. Paquette, M.C. Gelato, N. Hanson, M.Y. Tsai, M.J. Fazzari, E. Schoenfeld, And L. Hyman The Diabetes and Periodontal Therapy Trial (DPTT) American Association Of Dental Research Tampa, FL Annual Meeting 2012
  • Engebretson, S.P. , B. Michalowicz, M. Reddy, T. Oates, J. Katancik, D. Paquette, E. Seaquist, C.E. Lewis, D. Tripathy, P. Orlander, M. Gelato, N. Hanson, M.Y. Tsai, M. Fazzari, E. Schoenfeld, L. Hyman The Diabetes and Periodontal Therapy Trial (DPTT) Europerio 7 Vienna, Austria 2012
  • Engebretson, Steven P., Hyman, Leslie G., Michalowicz, Bryan S., Schoenfeld, Elinor R., Gelato, Marie C., Hou, Wei, Seaquist, Elizabeth R., Reddy, Michael S., Lewis, Cora E., Oates, Thomas W., Katancik, James A., Paquette, David W., Hanson, Naomi Q. and Tsai, Michael Y. The Diabetes and Periodontal Therapy Trial: High Sensitivity C-Reactive Protein IADR/PER Congress (September 10-13, 2014) in Dubrovnik, Croatia.

Department Publications 2012-2013

Manuscripts

  • Romanos AH, Geurs NC, Abou-Arraj RV. Pedicle Connective Tissue Graft With Novel Palatal Tunneling. Clinical Advances in Periodontics 14 March 2013: 1-8 (Accepted for publication).
  • Abou-Arraj RV, Geurs NC, Romanos AH. Autogenous Options for Soft Tissue Management of Extraction Sockets in the Anterior Maxilla. Clinical Advances in Periodontics 14 March 2013: 1-10 (Accepted for publication).
  • Abou-Arraj RV, Souccar NM. Periodontal Treatment of Excessive Gingival Display. Seminars in Orthodontics (Accepted for publication).
  • Geisinger ML, Holmes CM, Vassilopoulos PJ, Geurs NC, Reddy MS. Adjunctive Treatment of Chronic Periodontitis with Systemic Low-Dose Aspirin Therapy. Clin Adv Periodontics, 3(2): 195-199, 2012.
  • Geisinger ML, Holmes CM, Vassilopoulos PJ, Geurs NC, Reddy MS. Are Short Dental Implants Able to Demonstrate Predictable Success for Single Tooth Restorations? A Review of Current Evidence. Clinical Advances in Periodontics. Accepted for Publication April 2013.
  • Geisinger ML, Robinson M, Kaur M, Gerlach RW, Griffin R, Geurs NC, Reddy MS. Individualized Education Improves Clinical Outcomes of Pregnancy Gingivitis: A Pilot Study. Journal of Public Health Dentistry. Under Review
  • Geisinger ML, Geurs NC, Bain JL, Kaur M, Vassilopoulos PJ, Cliver SP, Hauth JC, Reddy MS. Oral Health Education and Therapy Reduces Gingivitis during Pregnancy. J Clin Periodontol Under Review
  • Geisinger ML, Holmes CM, Vassilopoulos PJ, Geurs NC, Reddy MS. Is laser disinfection an effective adjunctive treatment to bone augmentation for periimplantitis? A Review of Current Evidence. Clin Adv Periodontics Under Review
  • Beaudry KA, Geurs NC, Lemons JE and Reddy MS. Bone Formation Under Sinus Using Venous Coagulum. Clinical Advances in Periodontics Posted online on 20 May 2013.
  • Geurs N, Ntounis A, Vassilopoulos P, Reddy M. Ridge Preservation Using Growth Factors In Human Extraction Sockets. A Histologic and Histomorphometric Study. IJOMI submitted for publication.
  • Nevins M, Kao RT, McGuire MK, McClain PK, Hinrichs JE, McAllister BS, Reddy MS, Nevins ML, Genco RJ, Lynch SE, Giannobile WV. Platelet-Derived growth factor promotes periodontal regeneration in localized osseous defects: 36-Month extension results from a Randomized Controlled, Double-Masked Clinical Trial. J Periodontol. 84:456-464, 2013. (May 21, 2012 epub ahead of print) PMID: 22612364 PMC In Process
  • Natarajarathinam G, Chavali R, Reddy M, O’Neal J, McCracken M. Clinical efficacy of immediately loaded one-piece small diameter implants: A prospective 3-year cohort analysis. (submitted,JOMI, 2012)
  • Reddy MS, Morgan SL. Decreased Bone Mineral Density and Periodontal Management. Periodontology 2000:16:195-218, 2013. PMID: 23240950
  • Culpepper BK, Bonvallet PP, Reddy MS, Ponnazhagan S, Bellis SL. Polyglutamate directed coupling of bioactive peptides for delivery of osteoinductive signals on allograft bone. Biomaterials 34(5):1506-1513, 2013. PMID: 23182349 PMC3518561
  • Nevins M, Kao RT, McGuire MK, McClain PK, Hinrichs JE, McAlister BS, Reddy MS, Nevins ML, Genco RJ, Lynch SE, Giannobile WV. J Periodontol 84(4)
  • Palcanis K, Geiger B, O’Neal M, Werner K, Ivankova N, Evans R, Kennedy L. A mixed methods conceptual framework for curriculum enhancement of evidence-based dental education. J Dent Ed, 76:1600-1614, 2012.
  • Palcanis K, Lantz M. Continued competency in the specialties and academics. J Am Col Dent 79:28-32, 2012.

 

Monograph/non-peer-reviewed

  • Vassilopoulos PJ, Geurs NC, Geisinger ML. Factors that influence the position of Facial Gingival Position on Maxillary Anterior Teeth. Seminars in Orthodontics, 19(1); 37-48, 2013.

 

Abstracts

  • Abou-Arraj RV, Geisinger ML, Vassilopoulos PJ, Reddy M, Geurs NC. Gingival Biotype enhancement with acellular dermal matrix allografts. J Dent Res 92:915, 2013
  • Vassilopoulos PJ, Nguyen MA, Reddy MS, Geisinger ML, Geurs NC. Effect of growth factors on implant exposure and bone loss. J Dent Res 92:194, 2013.
  • Abou-Arraj RV, Geisinger ML, Vassilopoulos PJ, Reddy M, Geurs NC. Gingival Biotype enhancement with acellular dermal matrix allografts. J Dent Res 92:915, 2013
  • Kaur M, Bain JL, Geisinger M, Geurs N, Reddy M. Gingival inflammation reduction alters GCF cytokine levels in pregnancy gingivitis. J Dent Res 92:1433, 2013
  • Geisinger ML, Robinson MA, Kaur M, Litaker MS, Geurs NC, Reddy MS. Individualized education improves clinical outcomes of pregnancy gingivitis. J Dent Res 92:2497, 2013
  • Hulgan CA, Geisinger ML, Reddy MS. Assessment of dentist knowledge and management of diabetes mellitus patients. J Dent Res 92:3874, 2013
  • Geurs NC, O'Neal SJ, Reddy MS. Plaque, mucosal health and probing depth around laser ablated abutments. J Dent Res 92:2813, 2013.
  • Geurs NC, Reddy MS. A Controlled, Double-Blind, Randomized, Parallel-arm, Clinical Trial to Evaluate the Effectiveness of Laser-ablated Implant Abutments for Enhanced Oral Mucosal Healing AO meeting 2013
  • Engebretson S, Michalowicz B, Seaquist ER, Reddy M, et al. The Diabetes and Periodontal Therapy Trial (DPTT). J Dent Res 91:158472, 2012.