BERM MEMBERS

wickTimothy M. Wick, Ph.D.
Professor and Chair, Department of Biomedical Engineering
Co-Director, BioMatrix Engineering and Regenerative Medicine Center

Dr. Wick’s research interests are in development of bioreactors and bioprocesses for tissue engineering and development of flow systems to characterize cell adhesion to cells, matrices and biomaterials. In tissue engineering, his expertise ranges from fundamental studies of tissue development to bioprocessing for large-scale tissue production. Dr. Wick webpage

Murphy-UllrichJoanne E. Murphy-Ullrich, Ph.D.

Professor of Pathology and Cell Biology
Co-Director, BioMatrix Engineering and Regenerative Medicine Center
Director, FRET Imaging Microscopy Core Facility

Our lab was the first to identify thrombospondin (TSP) as one of a group of proteins that alters cell interactions with its matrix. Our research seeks to understand how the extracellular environment—matrix molecules and growth factors—regulate cellular processes such as growth, death, motility, and differentiation. Dr. Murphy-Ullrich webpage

 


 

agarwalAnupam Agarwal, M.D.
Thomas E. Andreoli Professor and Division Chief, Department of Medicine, Division of Nephrology

Dr. Agarwal’s research efforts include three main areas. (i) Studying the molecular regulation of the human heme oxygenase-1 (HO-1) gene in renal injury and in atherosclerosis. (ii) The functional significance of HO-1 gene expression is also being evaluated using both in vitro and in vivo systems in transgenic animal models of acute renal injury, transplantation and atherosclerosis. (iii) The active pursuit of gene delivery approaches in the kidney and the vasculature in animal models of transplantation using recombinant adeno-associated viral vectors.

Jonas_AlmeidaJonas Almeida, Ph.D.
Professor and Division Director, Department of Pathology, Divison of Informatics

My research is focused on the computational infrastructure for integrative bioinformatics. Specifically, it seeks to articulate the computational statistics aspects of data analysis with the data representation and management of its acquisition. This domain of enquiry seeks to understand and advance the emergence of unified computational environments that make optimal use of the scalability of cloud computing and the generality of semantic web representations. The practical application of this research is to enable the personalization of medicine by providing its computational vehicle.  Dr. Almeida webpage

Franklin_AmthorFranklin Amthor, Ph.D.
Professor, Department of Psychology

My long term interests include research on several kinds of artificial neural nets that function in a more biophysically realistic manner than those currently in vogue. I also am interested in biomedical instrumentation relevant to visual and other neural prostheses, particularly sensory protheses for the blind, and for diagnosis of eye and visual function disease. 

bellisSusan Bellis, Ph.D.
Professor, Department of Cell, Developmental and Integrative Biology
Co-Director, Cell and Molecular Analysis of Biomaterials Core Facility

Our laboratory analyzes the behavior of mesenchymal stem cells on the biomaterials in order to gain insight regarding how these materials can be optimized to promote cell adhesion and differentiation along the osteoblast lineage. Dr. Bellis webpage

jbaJoel Berry, Ph.D.
Research Associate Professor, Department of Biomedical Engineering

My research has focused on the development of experimental and computational flow models for vascular stent research. This work led to the discovery that most vascular stents create adverse blood flow disturbances potentially leading to their clinical failure and to the invention of a stent design that eliminates these disturbances.

BrottBrigitta C. Brott, M.D.

Associate Professor, Department of Medicine, Division of Cardiovascular Disease

Research interests include interventional cardiovascular therapies, myocardial cell therapy, endovascular device design, stent materials, drug-eluting stents, stent imaging, vascular compatibility of devices, large animal models of restenosis and myocardial infarction, dialysis fistula failure. Dr. Brott webpage

 

bridgesLouis Bridges, M.D., Ph.D.
Director of Division of Clinical Immunology and Rheumatology

 

Our research program is focused on identification of genetic and non-genetic influences on rheumatoid arthritis susceptibility, severity, and treatment response. Louis Bridges'webpage 

 

 

 

john-burgessJohn O. Burgess, D.D.S.
Professor of Prosthodontics
Assistant Dean for Clinical Research, School Of Dentistry

Current interests and projects involve mechanical and physical properties of dental materials, methods to improve in vitro testing, and model development to improve the ability of these models to predict their in vivo success. Additional research interests are clinical investigations of different dental restorative materials such as new adhesive bonding systems, low shrinkage composite resin materials, and innovative methods to measure in vivo restorative material wear. Dr. Burgess webpage

 

camataRenato P. Camata, Ph.D.
Associate Professor, Department of Physics

Research interests include laser and aerosols in nanomaterials fabrication, calcium phosphate bioceramics, hybrid nanomaterials and nanostructured semiconductors.
Dr. Camata webpage

 


aaron-catledgeAaron Catledge, Ph.D.
Assistant Professor, Department of Physics

Chemical Vapor Deposition (CVD) of diamond and other hard forms of carbon continues to be a very active area of research, particularly in the field of tribology where coatings of high hardness and low friction are required. The superlative properties of diamond, which include the highest known hardness and room temperature thermal conductivity, as well as the lowest compressibility of any material make it an ideal candidate for many applications. Much interest has been generated in the synthesis of hard carbon films exhibiting a wide range of structural forms and properties. The computer hard-disc, cutting tool, and biomedical implant industries are only a few examples in which hard carbon films (with names including “diamond”, “diamond-like carbon”, “nanostructured diamond”, and “tetrahedral amorphous carbon” in order to distinguish between different structural forms) have been investigated.  Dr. Catledge website



cchangChenbei Chang, Ph.D.
Associate Professor, Department of Cell, Developmental and Integrative Biology

The research in Dr. Chang’s laboratory focuses on growth factor signaling in early vertebrate development.

 

lisa-curtisLisa Curtis, Ph.D.
Assistant Professor, Department of Medicine, Division of Nephrology 

Our current research efforts are directed toward examining the following questions: (1) what is the identity of the reparative cells?; (2) where is the niche from which these reparative cells derive?; (3) what signaling induces the migration and epithelial incorporation of these renal reparative cells?; and (4) what is the effect of aging on this repair response? A greater understanding of the cell biology of renal repair by native kidney cells will provide further insight into the design of novel therapies in AKI.  Dr. Curtis webpage



darley_usmarVictor Darley-Usmar, Ph.D.
Vice Chair of Research, Department of Pathology
Director, Center for Free Radical Biology

We are examining the control of cell function mediated by reactive oxygen and nitrogen species through redox cell signaling mechanisms in the cardiovascular system. This is in the context of diabetes, alcohol toxicity and the cell signaling mediated by oxidized lipids. Dr. Darley-Usmar webpage

 

deanDerrick R Dean, Ph.D.
Associate Professor, Department of Materials Science and Engineering
BERM Steering Committee Member
Director, Nano-Matrix Scaffold Core

Dr. Dean's research focuses on the processing-structure-property relationships of polymers and multiphase polymer systems including nanocomposites, blends, and fiber-reinforced composites. Dr. Dean webpage

 

 

DeAndradeJoao A. De Andrade, M.D.
Associate Professor and Associate Director, Pulmonary Fellowship Program
Director, UAB Interstitial Lung Disease Program

Research interests include novel therapies for Idiopathic Pulmonary Fibrosis; Acute and Chronic Lung Injury; Markers of Rejection in Lung Transplantation. Dr. De Andrade webpage

 

dellitalia-louisLouis J. Dell’Italia, M.D.
Professor of Medicine, UAB Center for Heart Failure Research

Within the Specialized Center for Cardiac Dysfunction, Dr. Dell’Italia is the project leader of the Cardiac Imaging Core, which evaluates effect on in vivo function of various models of heart failure. He is an established, independent investigator in the field of cardiac hypertrophy and heart failure and in mechanisms of angiotensin II (Ang II) formation in the heart.


delucas2_2011Larry DeLucas, O.D., Ph.D.
Professor, Optometry
Director, Center for Biophysical Sciences and Engineering
Director, Comprehensive Cancer Center X-ray Core Facility

Dr. DeLucas' current research involves the study of membrane protein structure-function relationships. His laboratory has developed/validated a variety of novel technologies to support these studies, including technologies in protein expression, formulations development aimed at yielding more soluble and more stable protein, the use of predictive algorithms to support rapid determination of favorable protein crystallization conditions as well as ideal solutions for protein therapeutics. The lab is currently focused on the production, purification and crystallization of full-length cystic fibrosis transmembrane regulator protein (CFTR). The cystic fibrosis trans-membrane conductance regulator (CFTR) protein plays a key role in chloride conductance in normal airway cells. Single point mutations of CFTR can cause improper processing of the protein within epithelial cells or unresponsiveness to other interacting molecules important for CFTR activity. Dr. DeLucas's lab is also studying several G-protein coupled receptors (GPCRs) believed to play a critical role in prostate cancer.  Dr. DeLucas webpage

DingQiang (John) Ding, Ph.D.
Associate Professor, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine

My laboratory is primarily interested in understanding the molecular mechanisms by which the cellular functions of fibroblasts and myofibroblasts are regulated.
Dr. Ding webpage

 

Downs.NAL2013Crawford Downs, Ph.D.
Professor of Ophthalmology

Dr. Downs is a professor of ophthalmology and vice-chair of basic science research for the UAB Department of Ophthalmology. Dr. Downs joined the faculty in 2012 as the founding director of the department’s ocular biomechanics and biotransport program. This program is a multidisciplinary effort to study the underlying disease pathophysiologies of blinding eye conditions through the framework of biomechanics and biostransport. As part of the program, Dr. Downs’ current research focuses specifically on the impact of intraocular pressure (IOP), aging, and African heritage on the development and progression of glaucoma. Dr. Downs Web page

 


eber-1Alan E. Eberhardt, Ph.D.
Professor, Department of Biomedical Engineering
Director, Experimental Biomechanics Core

My research focuses on orthopaedic and injury biomechanics, through both experimental testing and finite element modeling, as well as tribiology and material testing. These research activities serve as important steps toward our long-term objective of optimal care for orthopaedic patients and improved protection for occupants in motor vehicle side impacts.

ElgavishRotem Elgavish, M.D., Ph.D.
Assistant Professor, Department of Neurology

Research interests involve neuroengineering applications in the diagnosis and treatment of epilepsy.  Dr. Elgavish webpage

feldmanDale S. Feldman, Ph.D.
Associate Professor, Department of Biomedical Engineering

My research interests include: biomaterials enhanced regeneration, tissue engineering, wound healing enhancement and characterization, tissue state and wound healing assessment, and degradable polymers for drug delivery systems and tissue scaffolds.

fengXu Feng, Ph.D.
Associate Professor, Division of Molecular and Cellular Pathology

My major research interest focuses on the molecular and cellular mechanisms underlying the differentiation and function of osteoclasts, our body’s principal bone resorbing cells.
Dr. Feng webpage

FloydCandace Floyd, Ph.D.
Assistant Professor, Department of Physical Medicine and Rehabilitation

The central focus of Dr. Floyd's research is to understand glial-neuronal interactions in pathophysiology of traumatic central nervous system injury. Additionally, the Floyd laboratory uses behavioral pharmacology techniques to evaluate potential new treatments for traumatic brain and spinal cord injury.


frostAndra R Frost, M.D.
Assistant Professor, Anatomic Pathology

Dr. Frost’s research is focused on understanding the effects of the stromal microenvironment of the breast on breast carcinogenesis and the progression of breast cancer. To this end, the Frost laboratory has utilized in vitro and in vivo model systems to explore the effects of human breast-derived fibroblasts and extracellular matrices on the progression of epithelial cells of the breast to carcinoma. Dr. Frost webpage

gilbertShawn R. (Skip) Gilbert, M.D.
Assistant Professor, Orthopaedic Surgery

I primarily investigating the role of the hypoxia inducible factor (HIF) pathway and angiogenesis in the skeleton using genetic and pharmacologic interventions and is also seeking to identify additional HIF activating pro-angiogenic compounds. Clinical research interests include publications and presentations on limb and spine deformity, fractures, skeletal maturation, and musculoskeletal infections. Dr. Gilbert webpage

Grytz.NAL2013Rafael Grytz, Ph.D.
Assistant Professor of Ophthalmology

The living eye tissues grow and remodel in response to mechanical, chemical and visual stimuli. Dr. Grytz seeks to understand the biomechanical mechanisms that underlie growth and remodeling in the eye during physiological and pathophysiological conditions. His particular research focus areas include growth and remodeling in glaucoma, keratoconus and myopia. Ongoing projects include the investigation of visually guided mechanisms controlling the axial length of the eye through scleral remodeling; loss and weakening of stromal collagen in keratoconus; and the IOP-dependent remodeling of the optic nerve head in glaucoma. Dr. Grytz’s research work focuses on the development of experimental and computational methods to quantify and simulate growth and remodeling in the eye. His experimental work involves the imaging of collagen remodeling in the living eye tissue. The experimental observations are translated into predictive simulation tools, which involve the development of computational multi-scale methods at various length scales, from the molecule to the organ. His laboratory’s goal is to provide predictive computational simulation tools that support the development of new diagnostics and patient-specific therapeutics in ocular diseases and conditions. Rafael Grytz webpage

Raymond E. Ideker, M.D., Ph.D.
Professor Emeritus of Medicine, Pathology, Physiology, and Biophysics, and Biomedical Engineering

ideker 150Research interests include sudden cardiac death and methods for its prevention; basic electrophysiologic mechanisms of ventricular and atrial arrhythmias; medical and surgical treatment of arrhythmias caused by coronary artery disease; computerized electrical and optical mapping systems to study ventricular tachycardia and fibrillation; and new techniques for the treatment of arrhythmias. Dr. Ideker's Web Page

 

JavedAmjad Javed, Ph.D.
Associate Professor, School of Dentistry, Department of Oral and Maxillofacial Surgery
The central focus of our laboratory is to understand the molecular mechanisms that govern the formation and remodeling of skeletal tissues such as Cartilage, Bone, Teeth and Tendon. We are exploring the signalling role of runt related transcription factor (Runx), in the coordinated regulation of various cell types (Chondrocyte, Osteoblast, Odontoblast, and Adipocyte) during skeletogenesis. Dr. Javed webpage

 

wjohnsonWalter H. Johnson Jr., M.D.
Associate Professor, Department of Pediatrics, Division of Pediatric Cardiology

Research interests include neoendothelialization of bioengineered extracorporeal circulatory support circuits to reduce thrombotic complications in patients with cardiopulmonary failure. Dr. Johnson webpage

 

HoWook_Jun_webHo-Wook Jun, Ph.D.
Assistant Professor, Department of Biomedical Engineering

Dr. Jun’s research interest focuses on the Biomimetic Nanotechnology. This includes synthetic extracellular matrix (ECM) mimic self-assembled nanofibers for the nanostructured tissue engineering such as tooth, bone, spine, and spinal cord regeneration; Synthetic bone marrow mimic nanostructured matrix to study stem cell and cancer cell development; Self-assembled functional nanoparticles for drug/gene delivery, molecular imaging, and cancer targeting; Functionalization of carbon nanotubes using self-assembled nanostructured materials for biological applications. Dr. Jun webpage

Keyser3Kent Keyser, Ph.D.
Assistant Vice President for Research

Dr. Keyser's research interests center on acetylcholine (Ach) and Ach receptor expression in the retina. Acetylcholine is used as a transmitter in many portions of the vertebrate nervous system and much information is available concerning the cells that contain it and its synthesis and release mechanisms. However, until recently little was known about Ach receptors and the neurons that express them. During the past several years various groups have 1) purified the ligand-binding (a) and structural (b) subunits of neuronal nicotinic acetylcholine receptors (nAChRs), 2) cloned their cDNAs, and 3) raised antibodies against them. These studies have revealed that there are at least 11 different subunits which, in various combinations, can theoretically yield a vast number of nAChR subtypes, each characterized by a unique subunit composition and pharmacological profile. Therefore, the effects of Ach or its agonists depends upon which receptor subtype is present. Acetylcholine is known to act as a transmitter in the retina and to affect the response properties of many ganglion cells, including those that display directional selectivity. These receptors appear to be present at both synaptic and extra synaptic locations. Dr. Keyser's research program involves the investigation of the normal pattern of expression of nAChRs in the retina during embryogenesis and in the adult animal, with the goal of understanding how activation of Ach receptor subtypes modulates visual processing. Another aspect of the research involves the detection of additional receptor subunits/subtypes and the determination of what receptor subunits are found together within individual receptor complexes. Among his long term goals are studies of the factors that regulate expression of different Ach receptor subtypes in various areas of the nervous system. Kent Keyser webpage

korfBruce R. Korf, M.D.
Professor and Chair, Department of Genetics

Dr. Korf is Wayne H. and Sara Crews Finley Professor of Medical Genetics and Chair, Department of Genetics. His major research interests are molecular diagnosis of genetic disorders and the natural history and treatment of neurofibromatosis. He has research grants from the NIH and from the Department of Defense to study genotype-phenotype correlations in NF1 and the natural history of plexiform neurofibromas in NF1.
krishnaN. Rama Krishna, Ph.D.
Professor of Biochemistry, Department of Biochemistry & Molecular Genetics

My laboratory is primarily interested in biomolecular NMR spectroscopy and structural biology. Recent work has centered around structure/function investigations and the characterization of motional dynamics in proteins and the development of computational methods and NMR methodologies for macromolecular structure refinement.

KucikDennis F. Kucik, M.D., Ph.D.
Chief, Pathology & Laboratory Medicine, VAMC
Associate Professor, Department of Pathology

The focus of our laboratory is cell adhesion and motility, with special emphasis on the role of the cytoskeleton in regulation of adhesion molecule function. A major focus is interactions between leukocytes and vascular endothelium. Dr. Kucik webpage

 

 

kimberlyRobert Kimberly, M.D.
Professor, Department of Medicine, Division of Clinical Immunology and Rheumatology
Senior Associate Dean for Research, School of Medicine
BERM Steering Committee Member

The main goal of my research is to understand the role of genetic factors in the normal function of the immune system and in development of immunological diseases such as systemic lupus erythematosus and systemic vasculitis.


DrLemonsJack E. Lemons, Ph.D.

Professor, Prosthodontics and Biomedical Engineering
BERM Steering Committee Member

My research focus has been on biomaterial and biomechanical properties as they relate to the biocompatibility of implant devices. My interests include dental biomaterials, biological tissue reaction to synthetic materials and biomechanics.




lucasLinda C. Lucas, Ph.D.

Provost
Professor, Department of Biomedical Engineering
BERM Steering Committee Member

Dr. Lucas’ research interest include the characterization and development of bioactive coatings for dental and orthopedic devices, biocompatibility evaluations of biomaterials, biocorrosion mechanisms of dental and orthopedic materials, and bone cement development.

 


louisPatrick J. Louis, D.D.S., M.D.
Associate Professor, School of Dentistry, Department of Oral and Maxillofacial Surgery

Research interests include dental implants, nanocrystalline diamond coatings for TMJ implants, and TMJ surgical outcomes. Dr. Louis webpage

 

 

macdougallMary J MacDougall, Ph.D.
James R. Rosen Chair for Dental Research
Associate Dean for Research, School of Dentistry
Director of Institute of Oral Health Research Professor, Department of Oral and Maxillofacial Surgery
BERM Steering Committee Member

Dr. MacDougall’s research centers on the molecular mechanisms associated with tooth formation, dental tissue-specific cytodifferentiation, extracellular matrix formation, tooth regeneration and related human genetic dental diseases.
Dr. MacDougall webpage

 

mountzJohn Mountz, M.D., Ph.D.
Professor, Department of Medicine, Division of Clinical Immunology and Rheumatology

Dr. Mountz is analyzing the cascade of molecular mediators that induce the formation of germinal centers in the BXD2 model of generalized autoimmunity to determine if targeted blocking of these events leads to a reduction in the production of autoantibodies and autoimmune disease.

 

pogwizdSteven Pogwizd, M.D.
Professor, Department of Medicine, Associate Director of Cardiovascular Research

My research interests include heart failure, arrhythmogenesis and sudden death.

 

 



ponnazhaganSelvarangan Ponnazhagan, Ph.D.

Associate Professor, Department of Pathology

The major research interest of my lab is adeno-associated virus (AAV)-mediated gene therapy of human diseases. The areas that we are currently working with AAV vectors are anti-angiogenic gene therapy for solid tumors, genetic immunization for cancer immunotherapy, and gene therapy for metabolic bone diseases.
Dr. Ponnazhagan webpage

 

Sumanth-PrabhuDr. Sumanth Prabhu, M.D.
Professor and Division Director, Department of Medicine, Division of Cardiovascular Disease

We are actively studying fundamental mechanisms of pathological remodeling in the failing heart, with a particular focus on inflammatory pathways (tumor necrosis factor, nuclear factor-kappaB) and cell types (e.g., macrophages). We are also interested in the interplay between inflammatory signaling and cardiac stem cell-mediated repair in the failing heart. Our clinical studies examine the effects of mechanical support (ventricular assist devices) on forward and reverse remodeling in human heart failure.  Dr. Prabhu webpage 

pritchardDavid G. Pritchard, Ph.D.
Professor, Department of Biochemistry & Molecular Genetics

Dr. Pritchard’s research interests are focused primarily on several different microbial products that contribute to the virulence of gram-positive bacteria, with particular emphasis on group B streptococcus (GBS) and Bacillus anthracis.

SandersPaul Sanders, M.D.
Professor, Department of Medicine, Division of Nephrology

The laboratory of Paul W. Sanders, M.D., has been funded through the National Institutes of Health for the past thirteen years to study the pathogenesis of salt-sensitive hypertension and hypertensive nephrosclerosis. More than 43 million Americans have high blood pressure and almost half are salt-sensitive.
Dr. Sanders webpage

Rajeev_SamantRajeev Samant, Ph.D.
Associate Professor, Division of Molecular and Cellular Pathology

Research interests include tumor progression and metastasis of cancer.  Dr. Samant webpage

sandersonRalph Sanderson, Ph.D.
Professor, Division of Molecular and Cellular Pathology

The long-term goal of the Sanderson lab is to determine how heparan sulfate regulates the microenvironment of bone homing tumors and to use that knowledge to design new cancer therapies. Dr. Sanderson webpage

 

dr. scripaRosalia Scripa, Ph.D.
Professor - Materials Science and Engineering

Dr. Scripa's primary area of research interest is in the growth and characterization of II-VI Semiconducting Compounds. The research has been funded by NASA in support of microgravity crystal growth experiments. Research interests also include failure analysis of ceramics and glass and development of ZBLAN glasses for optical fiber applications. Dr. Scripa's Web page

serraRosa Serra, Ph.D.
Professor, Department of Cell, Developmental and Integrative Biology

The overall goal of the laboratory is to understand the role and mechanism of TGF-ß signaling in embryonic and post-natal development and to apply this knowledge to the understanding and treatment of human degenerative and neoplastic disease.


Lalita_Shevde-SamantLalita Shevde-Samant, Ph.D.
Associate Professor, Division of Molecular and Cellular Pathology

Research interests include mechanisms that regulate tumor progression, metastasis and drug resistance; crosstalk between the tumor cells and their microenvironment.  Dr. Shevde-Samant webpage


shimamuraMasako Shimamura, M.D.
Associate Professor, Department of Pediatrics

My research interests are pediatric infectious diseases.


SiegalGene P. Siegal, M.D., Ph.D.

Professor and Director, Anatomic Pathology

Dr. Siegal has specifically been interested in studying tumor-matrix interactions during angiogenesis, tumor invasion and metastasis. Recent efforts by his group have been directed towards developing new reliable in vitro model systems for studying the effect of nutritional and other factors on cancer progression in humans.
Dr. Siegal webpage

sittitavornwongSomsak Sittitavornwong, D.D.S.
Assistant Professor, School of Dentistry, Department of Oral and Maxillofacial Surgery

My research interests include dental implants, maxillofacial trauma/pathology and bone reconstructive surgery.
Dr. Sittitavornwong webpage

Kenneth Sloan, Ph.D.
Associate Professor - Computer and Information Sciences

Research interests include contours, surfaces, and volumes; anatomy of the retina; and graphics techniques.

SongYuhua Song, Ph.D.
Assistant Professor, Department of Biomedical Engineering

Dr. Song's research interests are to understand biological systems with multiscale modeling approaches - Linking Mechanics to Biophysics and Biochemistry in Engineering, Biology and Medicine.

sthanamNarayana Sthanam, Ph.D.
Associate Professor, Department of Optometry

Research interest: surface proteins and proteinaceous filaments are used by gram-positive bacteria to colonize or invade human tissues. Structural view of these adhesive proteins and protein complexes at the atomic level and knowledge about their assembly and anchoring will enable us to invent strategies to prevent their attachment and thus block infection.
Dr. Sthanam webpage


ThannickalVictor Thannickal, M.D.
Professor and Director, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine

Research Interests:  Cellular/molecular mechanisms of lung repair and regeneration; Regulation of mesenchymal cell phenotypes; Reactive oxygen species (ROS)-generating NADPH oxidases (NOX) enzymes.  Dr. Thannickal webpage

Steven_ThomasSteven Thomas, M.D.
Assistant Professor, Department of Surgery, Division of General Surgery, Trauma, Burns and Surgical Critical Care Section
Director, UAB Burn Center

Research interests:  Burns, Burn Reconstructions, Burn Resuscitation, Complex Wound Care
Dr. Thomas webpage



thompsonAnthony Thompson, Ph.D.
Professor and Director, Department of Surgery, Division of Transplantation Research and Development

Research Interests:  Molecular mechanisms of angiogenesis, molecular mechanisms of transplantation biology, selective cell transplantation, reactive oxygen/nitrogen species in vascular injury and wound repair.  Dr. Thompson webpage

vyazovkin2Sergey Vyazovkin, Ph.D.
Associate Professor, Department of Chemistry

Our research interests are concerned with thermophysical properties and reactions of polymeric, pharmaceutical and energetic materials. We study these materials by using a variety of analytical techniques including Infrared (IR) Spectroscopy, Mass Spectrometry (MS), Thermogravimetric Analysis (TGA), Differential Scanning Calorimetry (DSC), Thermomechanical Analysis (TMA), Dynamic Mechanical Analysis (DMA), Polarized Light Microscopy (PLM), etc. Kinetic analysis of thermal data plays the key role in our work. We develop and apply our original kinetic methodology "Isoconversional Kinetic Analysis" also known as "Model-free Kinetics". 

 

vohraYogesh K Vohra, Ph.D.
Professor, University Scholar, School of Natural Sciences and Mathematics, Department of Physics
BERM Steering Committee Member

My research interests are growth and characterization of nanostructured materials, chemical vapor deposited single crystal diamond and designer diamond anvils and high pressure - high temperature materials research. Dr. Vohra webpage

waitePeter Waite, M.D.
Professor and Chair, School of Dentistry, Department of Oral and Maxillofacial Surgery

Research interest is surgical treatment of airway obstruction especially in obstructive sleep apnea, dental implants, bisphosphonate osteonecrosis, craniofacial deformities, cosmetic surgery, bone physiology and wound healing. Dr. Waite webpage

yao-1Xincheng Yao, Ph.D.
Assistant Professor, Department of Biomedical Engineering

Research is developing optics based instrumentations for biomedical imaging and biophysical studies. My recent research has been focused on development of advanced optical techniques for optical imaging of neural function using intrinsic optical responses associated with neural activities, and optical tweezers for micromanipulation and microfabrication.

 

zayzafoonMajd Zayzafoon, M.D., Ph.D.
Associate Professor, Division of Molecular and Cellular Pathology
Director, Center for Metabolic Bone Disease
BERM Steering Committee Member

The long-term goal of my laboratory is to develop novel therapeutic approaches for building and retaining bone mass in humans. Our research activities include understanding the transcriptional regulation of osteoblast differentiation and the role of calcium signaling in this process. Dr. Zayzafoon webpage

Yong20Zhou20photo202Yong Zhou, M.D., Ph.D.
Assistant Professor, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine

We are interested in understanding the mechanisms involved in regulation of mechano-induced latent TGF-beta1 activation and lung myofibroblast differentiation. Our current work focuses on identifying potential factors that regulate myofibroblast contractility and differentiation. The goals are to provide further mechanistic insights into the role of mechanotransduction in the pathogenesis of IPF and to develop effective therapeutic interventions for IPF treatment with a new approach.  Dr. Zhou webpage