January 2008

GTC Seminar Series, Co-sponsored by the UAB Liver Center
Tuesday, January 15, 2008
Mark A. Kay, M.D., Ph.D.
Professor
Departments of Pediatrics and Genetics
Director, Program in Human Gene Therapy
Stanford University School of Medicine
Stanford, CA
Title: RNAi, microRNAs and Gene Therapy
Place: Bevill Research Building, Rm. 170

February 2008

GTC Seminar Series
Tuesday, February 12, 2008
Christof von Kalle, M.D.
Head, Division of Translational Oncology of the German Cancer Research Center
National Center for Tumor Diseases (NCT), Heidelberg, Germany.
Institute for Molecular Medicine and Cell Research, University of Freiburg, 
Freiburg, Germany.
Division of Experimental Hematology, Cincinnati Children's Research Foundation, 
Cincinnati, Ohio
Title: The clonal fate of gene modified blood cells
Place: Bevill Research Building, Rm. 170

March 2008

GTC Seminar Series, Co-sponsored by the UAB Comprehensive Cancer Center
Tuesday, March 25, 2008
Frank McCormick, Ph.D, FRS
David A. Wood Distinguished Professor of Tumor Biology and Cancer Research
Director, UCSF Comprehensive Cancer Center & Cancer Research Institute
University of California San Francisco
San Francisco, CA
Title: Cancer therapy based on the RAS pathway
Place: Bevill Research Building, Rm. 170

May 2008

GTC Seminar Series, Co-sponsored by UAB Departments of Pediatrics and Genetics
Tuesday, May 6, 2008
Donald B. Kohn, M.D. Professor of Pediatrics
Division of Research Immunology/Bone Marrow Transplantation
Keck School of Medicine and Children's Hospital
University of Southern California
Los Angeles, CA
Title: Gene Therapy Using Hematopoietic Stem Cells
Place: Bevill Research Building, Rm. 170



May 2008

GTC Seminar Series, Co-sponsored by Susan G. Komen for the Cure-North 
Alabama Affiliate
Tuesday, May 20, 2008
Michael Sadelain, M.D.
Department of Medicine and Immunology Program
Gene Transfer and Somatic Cell Engineering Laboratory
Memorial Sloan Kettering Cancer Center
New York, NY
Title: Targeting tumors with genetically enhanced T lymphocytes
Place: Bevill Research Building, Rm. 170

 


September 2008

GTC Seminar Series 
Co-sponsored by the UAB Liver Center
Wednesday, September 24, 2008
Philip Ng, Ph.D.
Assistant Professor, Department of Molecular and Human Genetics
Baylor College of Medicine
Houston, TX
Title: Helper-dependent adenoviral vectors for gene therapy

Place: Kaul Human Genetics Building- Finley Conference Center
Time: 10:00 AM

October 2008

GTC Seminar Series
Co-sponsored by the Center for Neurodegeneration and Experimental Therapeutics (CNET) 
Thursday, October 9, 2008
Xandra O. Breakefield, Ph.D.
Professor, Department of Neurology, Harvard Medical School 
Geneticist, Molecular Neurogenetics Unit, Massachusetts General Hospital
Boston, MA
Title: How gliomas use microRNAs and exosomes to take over the brain

Place: Kaul Human Genetics Building- Finley Conference Center
Time: 10:00 AM

GTC Seminar Series
Co-sponsored by the Tumor Immunology Program of the UAB Comprehensive Cancer Center
Friday, October 24, 2008
Antoni Ribas, M.D.
Associate Professor, Departments of Medicine and Surgery
David Geffen School of Medicine
University of California, Los Angeles
Los Angeles, CA
Title: New Immunotherapies for Melanoma
Place: Kaul Human Genetics Building- Finley Conference Center
Time: 10:00 AM

November 2008

GTC Seminar Series
Co-sponsored by Expression Genetics (Danny Lewis)
Wednesday, November 12, 2008
Karen S. Aboody, M.D.
Assistant Professor, Divisions of Hematology/Hematopoietic Cell Transplantation & Neurosciences
Beckman Research Institute
City of Hope National Medical Center
Duarte, CA
Title: “Neural Stem Cell-Mediated Tumor Targeted Gene Therapy: Towards Clinical Trials”
Place: Kaul Human Genetics Building- Finley Conference Center
Time: 10:00 AM

December 2008

GTC Seminar Series
Co-sponsored by the UAB Dept. of Pharmacology and Toxicology
Thursday, December 11, 2008
Maria A. Croyle, Ph.D.
Associate Professor, Division of Pharmaceutics
University of Texas at Austin College of Pharmacy
Austin, TX
Title: “Pharmacology, Toxicology and Delivery Issues Associated with Recombinant 
Adenovirus-based Vaccines”
Place: Kaul Human Genetics Building- Finley Conference Center
Time: 10:00 AM


2007-2008 Gene Therapy Center Seminar Series

September 2007

GTC Seminar Series
Co-sponsored by the Center for Neurodegeneration and Experimental Therapeutics (CNET)
Wednesday, September 26, 2007
Maria Castro, Ph.D.
Co-Director, Gene Therapeutics Research Institute
Cedars-Sinai Medical Center
Los Angeles, CA
Title: Overcoming immune evasion by brain tumors: linking innate and adaptive immunity using 
gene-based therapeutics
Place: Bevill Research Building, Rm. 170

October 2007

GTC Seminar Series
Co-sponsored by the UAB Gregory Fleming James Cystic Fibrosis Research Center
Tuesday, October 16th, 2007
Joseph Zabner, M.D.
Professor, Department of Internal Medicine
Division of Pulmonary, Critical Care, and Occupational Medicine
University of Iowa, Iowa City, Iowa
Title: The Adenovirus Receptor and Adenovirus
Place: Bevill Research Building, Rm. 170

November 2007

GTC Seminar Series Co-sponsored by the Center for Neurodegeneration and Experimental 
Therapeutics (CNET)
Wednesday, November 28, 2007
Douglas Martin, Ph.D.
Assistant Professor
Scott-Richey Research Center
Auburn University College of Veterinary Medicine
Auburn, AL
Title: AAV Gene Therapy of Neurodegenerative Disease in a Feline Model
Place: Bevill Research Building, Rm. 170

December 2007

GTC Seminar Series
Co-sponsored by the Division of Pulmonary, Allergy and Critical Care Medicine
Wednesday, December 19, 2007
Steven M. Albelda, M.D.
William Maul Measey Professor of Medicine
Vice Chief, Pulmonary, Allergy, and Critical Care Division
Director of Lung Research; Co-Director, Thoracic Oncology Laboratories
University of Pennsylvania Medical Center
Abramson Research Center
Philadelphia, PA
Title: Immuno-gene Therapy for Malignant Mesothelioma: Successes and Challenges
Place: Bevill Research Building, Rm. 170



2006-2007 Gene Therapy Center Seminar Series



GTC Seminar Series 
May 22, 2007
Mark J. van Raaij
Ramon y Cajal Researcher
School of Pharmacy
Department of Biochemistry and Molecular Biology
University of Santiago de Compostela
Santiago de Compostela, Spain
Title: Structures of viral receptor-binding fibers
Place: Bevill Building, Room 170

GTC Seminar Series, Co-sponsored by Susan G. Komen for the Cure, North Central 
Alabama Affiliate
April 9, 2007
Dr. Albert B. Deisseroth, M.D., Ph.D.
President and Chief Executive Officer
Sidney Kimmel Cancer Center
San Diego, CA
Title: Vaccines for Cancer and Infectious Diseases
Place: Bevill Building, Room 170

GTC Seminar Series, Co-sponsored by the UAB Center for Nanoscale Materials 
and Biointegration
Monday, March 19, 2007
Esther H. Chang, Ph.D.
Professor of Oncology and Otolaryngology
Georgetown University Medical Center
Lombardi Comprehensive Cancer Center
Georgetown University Hospital
Washington, DC
Title: Materializing the Potential of Nanomedicine for Cancer Diagnosis 
and Therapy Place: Hill University Center, Alumni Auditorium

GTC Seminar Series
February 20, 2007
Laura Timares, Ph.D.
Assistant Professor 
Department of Dermatology 
University of Alabama at Birmingham
Title: Improving immune responses by using apoptosis-resistant dendritic cell vaccines 
Place: Finley Conference Center/Kaul Human Genetics Building 
Time: 10:00 AM

GTC Seminar Series
January 19, 2007
James M. Markert, M.D.
Professor
Department of Surgery
Director, Division of Neurosurgery
University of Alabama at Birmingham
Title: Oncolytic Viral Therapy
Place: Finley Conference Center/Kaul Human Genetics Building

GTC Seminar Series, Co-sponsored by The UAB Liver Center 
December 8, 2006
Jesús Prieto, M.D.
Professor of General Pathology 
University of Navarra, Campus Universitario
Pamplona 31080, Spain 
Title: "Gene Therapy of Experimental Liver Cirrhosis and Viral Hepatitis"
Place: Hill University Center - Alumni Auditorium
Time: 10:00 AM

GTC Seminar Series, Co-sponsored by the UAB Department of Microbiology 
Monday, November 20, 2006 
Carmen San Martin, Ph.D. 
Assistant Professor
Centro Nacional de Biotecnología (C.S.I.C.)
Madrid, Spain
Title: Polypeptides IX and IIIa: Recent Developments and Open Questions in 
Adenovirus Structure
Place: Bevill Biomedical Research Building, Room 170
Time: 2:00 PM 

GTC Seminar Series 
November 7, 2006
John C. Kappes, Ph.D. 
Associate Professor 
Department of Medicine
Division of Hematology and Oncology
University of Alabama at Birmingham
Title: Lentiviral Vectors: Biomedical Research Tools and Safety Considerations
Place: Finley Conference Center/Kaul Human Genetics Building
Time: 9:00 AM 

GTC Seminar Series, Co-sponsored by the UAB Division of Cardiovascular Disease
Tuesday, October 31, 2006
Duncan J. Stewart, M.D.
Professor and Director, Division of Cardiology, University of Toronto
Head, Division of Cardiology and Associate Director of Research at 
St. Michael's Hospital
Toronto, Ontario, Canada
Title: Gene Therapy for Cardiovascular Disease: A Work in Progress
Place: Hill University Center (HUC), Alumni Auditorium
Time: 10:00 AM 

GTC Seminar Series 
Monday, September 25, 2006
Tim M. Townes, Ph.D. 
Professor and Chairman
Department of Biochemistry & Molecular Genetics
University of Alabama at Birmingham
Title: Globin Gene Regulation and Genetic Therapies for Sickle Cell Disease
Place: Finley Conference Center/Kaul Human Genetics Building
Time: 9:00 AM 



2005-2006 Gene Therapy Center Seminar Series



Gene Therapy Seminar Series
Tuesday, May 17, 2006
Richard C. Mulligan, M.D., Ph.D.
Mallinckrodt Professor of Genetics
Department of Genetics, Harvard Medical School
Professor of Pediatrics
Children's Hospital
Title: TBA

Wednesday, April 12, 2006
Inder M. Verma, Ph.D.
American Cancer Society Professor of Molecular Biology
Laboratory of Genetics
Salk Institute for Biological Studies 
LaJolla, California
Title: TBA

Gene Therapy Seminar Series 
Wednesday, February 22, 2006
Joseph C. Glorioso III, Ph.D.
Director, Molecular Medicine Institute
Professor and Chairman 
Department of Molecular Genetics and Biochemistry
University of Pittsburgh, School of Medicine
Pittsburgh, PA

Gene Therapy Seminar Series
Wednesday, January 18, 2006
Dusty Miller, Ph.D.
Professor
Department of Pathology
Fred Hutchinson Cancer Research Center
University of Washington School of Medicine
Seattle, WA
Title: TBA

Gene Therapy Seminar Series
Thursday, November 17, 2005
Savio L.C. Woo, Ph.D.
Professor and Chairman
Department of Gene and Cell Medicine
Mount Sinai School of Medicine
Title: "Gene Therapy for Cancer"

Gene Therapy Seminar Series
Tuesday, November 1, 2005
Hongju Wu, Ph.D.
Research Assistant Professor
Department of Obstetrics/Gynecology
Division of Human Gene Therapy 
Title: "Adenovirus-mediated Gene Delivery for Brain Tumors"

Gene Therapy Seminar Series
Tuesday, October 4, 2005
Theresa V. Strong, Ph.D.
Associate Professor
Department of Medicine
Division of Hematology/Oncology
Title: "Bedside to Bench: Reverse Translational Research Identifies a Potential Role 
for hDIg in Melanoma"


2004-2005 Gene Therapy Center Seminar Series



Wednesday, May 18, 2005
E. Antonio Chiocca, M.D.
Professor and Dardinger Family Professor
Department of Neurological Surgery
The Ohio State University
Columbus, OH
"Oncolytic HSV-1 for Brain Tumor Therapy"

Wednesday, May 4, 2005
James S. Norris, Ph.D
Professor and Chairman
Department of Microbiology / Immunology
Medical University of South Carolina
Charleston, South Carolina
"Modification of Ceramide Metabolism to Induce a Pro-Apoptotic 
Phenotype that Enhances AdFasL Cancer Gene Therapy"

Friday, April 1, 2005
Phoebe L. Stewart, Ph.D.
Associate Professor
Dept. of Molecular Physiology & Biophysics
Vanderbilt University Medical Center
Nashville, TN
"CryoEM Imaging of Adenovirus Vectors and Adenovirus-Antibody Complexes"

Tuesday, March 8, 2005
Sarah Ferber, Ph.D.
Head of the Endocrine Research Unit
Institute of Endocrinology
Sheba Medical Center
Tel Hashomer, Israel
"Liver as a Pancreatic Progenitor Tissue: Potential Cell Replacement Therapy for Diabetes"
Co-sponsored by UAB Human Pancreatic Islet Transplant Program 

Tuesday, February 22, 2005
William C. Aird, M.D.
Chief
Division of Molecular and Vascular Medicine
Department of Medicine
Beth Israel Deaconess Medical Center
Boston, MA
"Understanding Endothelial Heterogeneity"

Wednesday, December 15, 2004
R. Scott McIvor, Ph.D.
Professor of Genetics, Cell Biology and Development
Director, Gene Therapy Program
Institute of Human Genetics
University of Minnesota
Minneapolis, MN
"The Sleeping Beauty Transposon System as a Vector for Gene Therapy"

Wednesday, November 17, 2004
Robin J. Parks, Ph.D.
Scientist
Molecular Medicine Program
Ottawa Health Research Institute
Ottawa, Canada
"Adenovirus Protein IX: A Little Protein with a Big Story"
Bevill Biomedical Research Building 170

Friday, October 22, 2004
Gary Nabel, M.D., Ph.D.
Director
Vaccine Research Center
National Institutes of Health
Bethesda, MD
"Viruses, Vectors, and Human Disease"

Tuesday, September 28, 2004
Andrea Amalfitano, D.O., Ph.D.
Associate Professor of Pediatrics
Duke University
Durham, NC
"Exploring Adenovirus Vector/Host Interactions to Foster Safe and 
Efficacious Gene Therapy for Human Diseases."


2003-2004 Gene Therapy Center Seminar Series


Tuesday, October 14, 2003
Phillip L. Leopold, Ph.D.
Assistant Professor of Biochemistry in Medicine
Department of Medicine
Division of Pulmonary and Critical Care Medicine
New York Weill Cornell Medical Center
"Post-Endocytic Trafficking of Adenovirus"

Thursday, November 6, 2003
Michael A. Barry, Ph.D.
Associate Professor
Departments of Molecular and Human Genetics, Immunology
Baylor College of Medicine
Department of Bioengineering
Rice University
"Cell Targeting Technologies for Gene Therapy"

Thursday, December 18, 2003
Paul B. Fisher, Ph.D.
Professor of Clinical Pathology
Department of Pathology
Columbia University
"Is mda-7/IL24 a Magic Bullet for Cancer?"

Tuesday, February 24, 2004
Raymond J. Pickles, Ph.D.
Assistant Professor of Medicine
University of North Carolina at Chapel Hill School of Medicine
"Understanding the Target Cell when Developing Viral Vectors for Therapeutic Gene 
Delivery to the Lung"

Tuesday, March 16, 2004
Patrick Hearing, Ph.D.
Professor
Department of Molecular Genetics and Microbiology
Stony Brook University School of Medicine
"Regulation of PML Nuclear Body Function During Adenovirus Infection"

Thursday, April 1, 2004
Tanja D. de Gruijl, Ph.D.
Department of Medical Oncology
Division of Immunotherapy
Vrije Universiteit Medical Center
Amsterdam, The Netherlands
"Dendritic Cell-Targeted Adenoviral Gene Transfer for Tumor Immunotherapy"

 Wednesday, April 28, 2004
Lily Wu, M.D., Ph.D.
Assistant Professor
Departments of Urology, Pediatrics and Molecular & Medical Pharmacology
David Geffen School of Medicine at UCLA
"Molecular Imaging and Gene Therapy in Animal Models of Cancer"

Thursday, May 20, 2004
Theodore Friedmann, M.D.
Professor, Department of Pediatrics
Director, Program in Human Gene Therapy
University of California, San Diego School of Medicine

Thursday, June 17, 2004
John J. Nemunaitis, M.D.
Associate Director, Clinical Research
US Oncology
Mary Crowley Medical Research Center
Dallas, TX
"Gene Vaccines in Non Small Cell Lung Cancer"


2002-2003 Gene Therapy Center Seminar Series


Wednesday, October 16, 2002
William S.M. Wold, Ph.D.
Professor and Chairman
Department of Molecular Microbiology & Immunology
St. Louis University School of Medicine

Tuesday, November 5, 2002
Patrick W.K. Lee, M.D.
Professor
Department of Microbiology & Infectious Diseases
University of Calgary
'Reovirus as an Oncolytic Agent'

Wednesday, November 13, 2002
Gerald G. Krueger, M.D.
Professor of Dermatology
Cumming Presidential Endowed Chair
University of Utah
'The Challenge of Using Genetically Modified Fibroblasts As A Vehicle for Gene Therapy'

Wednesday, November 20, 2002
Noriyuki Kasahara, M.D., Ph.D.
Assistant Professor
Departments of Pathology & Biochemistry
University of Southern California
'Lentivectors, RCRs, and Trojan Horses:
New Strategies for Improving Therapeutic Gene Transfer In Vivo'

Wednesday, December 11, 2002
John Hay, M.D.
Assistant Professor of Medicine & Pathology
New York University School of Medicine
'Strategies to Enhance the Oncolytic Activity of Adenoviral Vectors'

Tuesday, January 14, 2003
Dr. Andre Lieber
Research Associate Professor
University of Washington
'Structural Determinants and Pathways for Adenovirus Infection In Vitro and In Vivo'

Wednesday, February 12, 2003
Roberto Cattaneo, Ph.D.
Professor of Biochemistry & Molecular Biology
Mayo Foundation
'Measles Virus Entry: Mechanisms and Retargeting' 

Tuesday, March 11, 2003
Katherine High, M.D.
Director of Research
Hematology Division
Children's Hospital of Philadelphia

Tuesday, April 22, 2003  
D.C. Yu, Ph.D.
Director
Oncolytic Virus Research
Cell Genesys, Inc.
Selectively Replicating Oncolytic Adenoviruses: Clinical Progress and Challenges 
for the next Generation

Tuesday, May 13, 2003
Glen N. Barber, Ph.D.
Associate Professor
Department of Microbiology and Immunology
University of Miami School of Medicine


2001-2002 Gene Therapy Center Seminar Series


Wednesday, October 24, 2001
Ronald G. Crystal, M.D.
Director, Institute of Genetic Medicine
New York Presbyterian Hospital
Weill Medical College of Cornell University
New York, NY 
"Genetic Modification of Dendritic Cells to Enhance Host Defenses"

Friday, November 16, 2001
K. Dane Wittrup, Ph.D.
J.R. Mares Professor
Chemical Engineering & Bioengineering
Massachusetts Institute of Technology
Cambridge, MA 
"Directed Evolution of Protein Recognition, Stability and Expression by Yeast Surface Display" 

Friday, January 11, 2002
Per Eystein Lønning, M.D., Ph.D.
Professor
Department of Oncology
Haukeland University Hospital
Bergen, Norway
"Translational Research on Gene Defects with Respect to Chemoresistance in Cancer"

Wednesday, February 6, 2002
Dan J. Von Seggern, Ph.D.
Assistant Professor
Department of Immunology
The Scripps Research Institute
La Jolla, CA
"Pseudotyped Adenoviruses: Targeted Gene Delivery and Determination of Viral Tropism"
West Pavilion E

Thursday, February 21, 2002
Jeffrey S. Chamberlain, Ph.D.
Professor
Department of Neurology
University of Washington School of Medicine
Seattle, WA
"Prevention and Reversal of Muscular Dystrophy by Gene Therapy"

March 13-14, 2002
Michael Imperiale, Ph.D.
Professor
Interim Co-Director, Center for Gene Therapy
University of Michigan Medical School
Ann Arbor, MI

April 18, 2002
Stephen Russell, M.D., Ph.D.
Director
Molecular Medicine Program
Mayo Clinic
Rochester, MN
"Exploiting Attenuated Measles Viruses for Cancer Therapy"

May 14-15, 2002
Malcolm K. Brenner, M.D., Ph.D.
Professor of Medicine and of Pediatrics
Director, Center for Cell and Gene Therapy
Baylor College of Medicine

May 30, 2002
Andrew H. Baker, Ph.D.
Senior Lecturer in Molecular Medicine
Department of Medicine and Therapeutics
University of Glasgow, Scotland
"Targeted Adenoviral Vectors"


2000-2001 Gene Therapy Center Seminar Series


Tuesday, March 13, 2001
Dr. Roland Kontermann, Ph.D. 
Phillips-University of Marburg, Germany 
"Targeting of vectors and effectors with recombinant bispecific antibodies". 

Thursday, March 22, 2001
Dr. H. M. Pinedo
Chair of Medical Oncology
Vrije University of Amsterdam
Amsterdam, The Netherlands

Tuesday, April 24, 2001
Thomas W. Dubensky, Jr., Ph.D. 
Senior Director of Virus Research, Onyx Pharmaceuticals 
"The Development of Selectively Replicating Adenoviruses as Cancer Therapeutics: 
Promise of Clinical Efficacy and Future Directions" 

Thursday, May 17, 2001
Heshan (Sam) Zhou, Ph.D.
Research Assistant Professor
Department of Molecular and Human Genetics
Center for Cell and Gene Therapy
Baylor College of Medicine
Houston, TX
"Development of Adenovirus Vector System - 
From E2a Deletion to Gutless Strategy and to Conditional Replication"