Novel mechanism involved in memory discovered

Memory paperThe role of a histone subunit known as H2A.Z, which could have therapeutic ramifications for conditions including dementia or even post-traumatic stress disorder, is revealed in UAB laboratory research published online in Nature.

 “Memory improved with the absence of H2A.Z, which was unexpected, since we hypothesized that H2A.Z would be a necessary part of memory formation in normal situations,” said J. David Sweatt, Ph.D., chair of the Department of Neurobiology and director of the Evelyn F. McKnight Brain Institute, who led the research team. “This gives us an intriguing new target for therapies for conditions involving memory loss or poor memory formation.”

Read more