As with the Yang-King, Margulies-Meaney and Darvish-Crandall components, this project is also evaluating, enhancing, and improving the predictive capabilities of SIMon with the ultimate goal of replacing existing head injury criterion (HIC) as the regulatory standard for motor vehicle safety.

Specifically, research at the University of Alabama at Birmingham involves experiments to determine if there is a cumulative effect or cumulative damage (read: cumulative pathology) that develops as multiple injury cycles are repeated. The premise is fairly straightforward: If more axons are damaged as multiple injury cycles are repeated, they should be easier to identify with appropriate histological techniques.