The research plan and goals for SCIB

The SCIB was established at UAB to improve research on human injury resulting from motor vehicle crashes, and that remains its primary goal. Currently, 17 projects across three research domains are seeking to improve our understanding of human interaction with machines in vehicle crashes. Some of the research projects are not something that an average person might recognize immediately as having a vehicle crash focus. However, all the SCIB’s research taken together promises to improve the understanding of what happens to the human body in a vehicle crash and thus improve research into better safety standards and more accurate post-injury treatment both on the scene and in the hospital setting. It is foundational research, critical to lowering injury rates, increasing survival statistics, and improving human performance and function after injury.

Said simply, the primary goals of SCIB are to lessen the chances you will die or be injured in a vehicle crash, and to improve the chances that if you are injured, you will have as few long-term impairments as possible. The primary focus currently is on injuries to the head, neck and extremities among children and adults.

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Research Domain One deals with head and brain injury; the domain director is Dr. David Meaney of the University of Pennsylvania. The main focus of this Domain is to improve the predictive capabilities of a Simulated Injury Monitor, or SIMon, a “next generation” (G2) injury assessment tool developed by Dr. Rolf Eppinger of the National Highway Transportation Safety Administration (NHTSA). Essentially, SIMon takes a wide range of data on how the body reacts to a deceleration event, and predicts what type of injuries a specific set of factors (such as speed and point of impact) will cause. A computational model relies on good data, without which its calculations will not be accurate or helpful. The various research projects under Research Domain One are working together to improve the data used to make calculations and to refine and improve the computational power of SIMon.

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The overall goal of work in Research Domain Two is to enhance the understanding of neck injury mechanisms. The research projects in this Domain focus specifically on catastrophic neck injury, pediatric neck injuries, and whiplash injuries. One prominent feature in several of the research projects is determining the load tolerances of various configurations of the neck and spine; that is, what level of pressure, impact or deceleration causes injury, and how the interaction of parts of the neck and spine during an injury event result in greater or lesser injury in response to the loading. Some of the projects look at only one facet of the equation, such as the mechanical properties of the cervical spine or the way children’s bodies respond to deceleration and impact events as opposed to the way adult bodies respond. Some of these data will also be used in improving SIMon’s predictive accuracy.

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Research Domain Three deals with measuring and assessing human tolerances and looking at the ways the human body responds to traumatic loading. Recognizing that much of the current data on human tolerances – on how varying loads affect muscles, bones, brain and integrated body systems during a deceleration event – are not based on a representative sample of the entire population, this Domain emphasizes assessment of the effects of such variables as aging and population demographics, on load responses. Research in this domain includes projects on both body system responses to injury events and computational assessment tools for increasing the scope and accuracy of future biomechanics research.

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Projects and investigators currently active in SCIB research
Projects By Research Domain, Title, Principal Investigator(s) and Institution

Research Domain One: Head and Brain Injury
Domain Director: David Meaney, University of Pennsylvania

Long Term Vision

Evaluating and Enhancing the Predictive Capabilities of SIMon
King Yang & Albert King, Wayne State University

Measuring Brain Tissue Injury Thresholds
Susan Margulies & David Meaney, University of Pennsylvania

Impact Acceleration Tests and Material Properties of Rat Brain
Kurosh Darvish, Temple University & Jeff Crandall, University of Virginia

Small Animal Model of Diffuse Axonal Injury
Evangelos Eleftheriou, Jean Peduzzi-Nelson and Jay Mythaler, University of Alabama at Birmingham

Brain Cell and Tissue Tolerance to Traumatic Loading
Michelle LaPlaca, Georgia Institute of Technology

Biomechanics of Brain Injury: Experimental Studies
Philip Bayly, Washington University in St. Louis

Data Archive of Non-Human Primate Brain Injury Studies
Susan Margulies, University of Pennsylvania

Research Domain Two: Neck and Whiplash Injury
Domain Director: Barry Myers, Duke University

Long Term Vision

Quantitative Tolerance Criteria for SIMon: Cell Death and Dysfunction
Barclay Morrison, III, Columbia University

Prevention of Head and Neck Impact Injury by Improved Helmet Design (Completed 2002)
Barry Myers, Duke University

Pediatric Head and Neck Impact Injury
Barry Myers, Duke University

Computational Modeling of the Cervical Spine Musculature
Marcus Pandy, University of Texas at Austin (thru 01.05)
Barry Myers, Duke University

Determination of Cervical Spine Substructure Mechanical Properties
J. Marcus Hollis, University of South Alabama

Injury Mechanism of Facet Mediated Whiplash Neck Pain
Beth Winkelstein, University of Pennsylvania

Research Domain Three: Human Tolerance
Final Report: Effects of Impact Loading on Articular Cartilage
Domain Director: Kerry Athanasiou, Rice University

Long Term Vision

Effects of Impact Loading on Articular Cartilage
Kerry Athanasiou, Rice University

The Effects of Orbital Muscles on Eye Injury Biomechanics
Stefan Duma, Virginia Polytechnic Institute and State University (Virginia Tech)

Evolutionary Design of Finite Element Meshes for Injury Biomechanics Research
Lewis Payton, Auburn University
Brian Carnahan (2003-2004)

Feasibility Study for a Miniature 9-Axis Accelerometer Array
William Mills, Konigsberg Instrument Company

Numerical and Emperical Investigations of Automotive Related Aortic Injury
King Yang , Wayne State University

The SCIB's Digital Child Project
Numerical Model Development: Phase 1 and 2 Overview

Russ Fine and Jay Goldman, University of Alabama at Birmingham

Numerical Model Development: Phase 1
Identifying Pediatric Anatomy for Model Development

Al King, Wayne State University

Numerical Model Development: Phase 2
Development of Finite Element Meshes for Child Models

Bharat Soni, University of Alabama at Birmingham

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SCIB researchers: News and Activities

Researchers affiliated with the SCIB are very active in their chosen fields. This section provides links to information on their activities and news articles about them, on both SCIB and non-SCIB research.

2006 News

 

  • Philip V. Bayly was installed as the Lilyan and E. Lisle Hughes Professor of Mechanical Engineering at a March 8 ceremony in Uncas A. Whitaker Hall for Biomedical Engineering. Bayly's research interests involve dynamics in mechanical and biomedical systems. Bayly has been on the faculty of the Department of Mechanical and Aerospace Engineering since 1993; he holds a joint appointment in the Department of Biomedical Engineering. Dr. Bayley is the principal investigator of an important SCIB-sponsored project "Biomechanics of Brain Injury: Experimental Studies." The objective of this research effort is to provide experimental data for validation of numerical studies of head injury. Two questions are addressed: First, what are the linear and angular accelerations of the skull during a mild head impact typical of contact sports? Second, how does the brain deform in response to angular acceleration of the skull

2005 News

2004 News

  • Dr. Stefan Duma was featured in the Virginia Tech Research magazine in December 2004, in an article called “On A Quest to Banish Injuries”. Dr. Duma’s SCIB-sponsored research looks at in situ cadaveric eyes to learn more about the role of the eye’s oblique muscles in serious eye injury events. (Link for the article: http://www.research.vt.edu/resmag/2004resmag/Duma.html)

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