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Recent Publications: Kin, N.W., Stefanov, E.K., Dizon, B.L.P., Kearney, J.F. Antibodies generated against conserved antigens expressed by bacteria and allergen-bearing fungi suppress airway disease. J Immunol: 2012 Sep 1; 189 (5), 2246-2256. Summary Kearney, J.F. (2012),
"Innate-like B cells", in Gordon, S. (ed.), Cells of the Innate Immune
System: Roles in health and disease, The Biomedical & Life Sciences
Collection, Henry Stewart Talks Ltd, London. Online Foote, J.B., Mahmoud, T.I., Vale, A.M., Kearney, J.F. Long-term maintenance of polysaccharide-specific antibodies by IgM-secreting cells. J Immunol: 2012 Jan 1; 188(1): 57-67. Epub 2011 Nov 23. Summary Kin, N.W., Chen, Y., Stefanov, E.K., Gallo, R.L., Kearney, J.F. Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function. Eur J Immunol: 2011 Oct; 41(10): 3006-16. Epub 2011 Aug 31. Summary Mahmoud, T.I., Schroeder, H.W., Jr., Kearney, J.F. Limiting CDR-H3 diversity abrogates the antibody response to the bacterial polysaccharide alpha-1,3 dextran. J Immunol: 2011 Jul 15; 187(2): 879-86. Epub 2011 Jun 15. Summary You,
Y., Myers, R.C., Freeberg, L., Foote, J., Kearney, J.F., Justement,
L.B., Carter, R.H. Marginal zone
B cells regulate antigen capture by marginal zone macrophages. J Immunol: 2011 Feb
15;186(4):2172-81. Epub 2011 Jan 21. Summary Foote, J.B., and Kearney, J.F. Generation of B Cell memory to the bacterial polysaccharide alpha 1-3 dextran. J Immunol: 183:6359-6368, 2009. Summary Mahmoud, T.I., Kearney, J.F. Terminal deoxynucleotidyl transferase is required for an optimal response to the polysaccharide alpha-1,3 dextran. J Immunol: 2010 Jan 15;184(2):851-8. Epub 2009 Dec 16. Summary Oliva, C., Turnbough, C. L. , Jr., and Kearney, J. F. 2009. CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages. Proc Natl Acad Sci U S A: 106:13957-13962, 2009. Summary Kin, N.W., Crawford, D.M., Liu, J., Behrens, T.W., and Kearney, J.F. DNA Microarray Gene Expression Profile of Marginal Zone versus Follicular B Cells and Idiotype Positive Marginal Zone B Cells before and after Immunization with Streptococcus pneumoniae. J. Immunol: 180:6663-74, 2008. Summary Lisanby, N., Swiecki M.K., Dizon, B., Pflughoeft. K., Koehler T., Kearney J.F. Cathelicidin administration protects mice from Bacillus anthracis spore challenge. J. Immunol: 181:4989-5000, 2008. Summary Oliva, C., Swiecki, M.K, Griguer, C., Lisanby, M., Bullard, D., Turnbough, C.T., Jr., and Kearney, J.F. The integrin Mac-1 (CR3) mediates internalization and directs Bacillus anthracis spores into professional phagocytes., PNAS: 105:1261-1266, 2008. Summary Won W-Jai., Bachman, M.F., and Kearney, J.F. Expression of CD36 by developing B cell subsets and during their responses to antigen., J.Immunol: 180, 230-237, 2008. Summary Steichen, C.T, Kearney, J. F., and Turnbough, C.L. Jr. Non-uniform assembly of the Bacillus anthracis exosporium and a bottle cap model for spore germination and outgrowth: Mol. Microbiol. 64:359-367, 2007. Summary Berland, R., Fernandez, L., Kari, E., Han, J.H., Lomakin, I., Akira, S., Wortis, H.H., Kearney, J.F., Ucci, A.A., Imanishi-Kari, T. Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. Immunity 25: 429-440, 2006. Summary Boydston, J.A., Yue, L., Kearney, J.F., and Turnbough. C.T., Jr. The ExsY protein is required for complete formation of the exosporium of Bacillus anthracis. J. Bacteriol.: 188: 7440-7448, 2006. Summary Swiecki, MK, Lisanby, M.W, Turnbough, CL, Jr., and Kearney, JF. Monoclonal antibodies for Bacillus anthracis spore detection and functional analyses of spore germination and outgrowth. J. Immunol.:15;176: 6076-84, 2006. Summary Won, W-Jai., Foote, J.B., Odom, M., Pan, J., Kearney, J.F., and Davis , R.S. FcHR3 is a novel immunoregulatory marker of marginal zone and B1 B cells: J. Immunol. 177: 6815-23, 2006. Summary Attanavanich, K. and Kearney, J.
F. Marginal zone but not
follicular B cells are potent activators of naïve CD4 T cells. J. Immunol.
172:803-811, 2004. Summary Martin, F. and Kearney, J.F. Marginal-zone B cells. Nature Reviews Immunology 2(5):323-35, May 2002. Summary Thai, T.H., Purugganan, M.M., Roth, D.B., and Kearney, J.F. Distinct and opposite diversifying activities of terminal transferase splice variants. Nat. Immunol. 3(5):457-62, May 2002. Summary Won, W.J. and Kearney, J.F. CD9 is a unique marker for marginal zone B cells, B1 cells, and plasma cells in mice. J. Immunol. 168(11):5605-11, Jun 1, 2002. Summary Benedict, C.L., Gilfillan, S., and Kearney, J.F. The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform. J. Exp. Med. 193:89-99, 2001. Summary Martin, F. and Kearney, J.F. B1 cells: Similarities and differences with other B cell subsets. Curr. Opin. Immunol. 13:195-201, 2001. Summary Martin, F., Oliver, A.M., and Kearney, J.F. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14:617-629, 2001. Summary Martin, F. and Kearney, J.F. Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk. Immunity 12(1):39-49, 2000. Summary Benedict, C.L. and Kearney, J.F. Increased junctional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice. Immunity 10:607-617, 1999. Summary |