The Comprehensive Arthritis, Musculoskeletal and Autoimmunity has worked to establish collaborative synergies across schools, departments and divisions.  Building on its traditional strengths in immunology and autoimmunity, the Center faculty has developed programs in translational human genetics (focusing on the immunogenetic basis of autoimmune disease) and in outcomes and population-based research, in addition to research themes encompassing experimental therapeutics, bone cartillage and connective tissue, immunology, autoimmunity, autoimmunity and inflammation and neuroimmunology.  These programs leverage the emergence of team science -- the bringing together of individuals with different yet highly complementary skills -- and the opportunities in personalized medicine by bringing a deep understanding of genetic polymorphisms together with rich, longitudinal clinical phenotypic data.   Through collaborative synergies and partnerships, the Center has strengthen the research capacity in discovery and translational research across disciplines and has facilitated more effective clinical care.