Mucosal HIV & Immunobiology Center
- Last Updated on June 05, 2013
Mucosal HIV and Immunobiology Center (Phillip D. Smith, MD, Director; NIDDK 5R24DK064400)
The UAB Mucosal HIV and Immunobiology Center supports research on the interaction between microbes and mucosal tissues by integrating the investigative efforts of UAB’s world-class mucosal immunology programs. The Center seeks to speed development of therapies and vaccines for a spectrum of mucosal diseases by facilitating an interdisciplinary environment, uniting investigators in mucosal diseases with those from a wide variety of other disciplines at UAB. The Center also supports Core resources and expertise, including:
- Genetically-Defined Microbe Core;
- Molecular Pathology and Human Cell/Tissue Core; and
- Gnotobiotic and Genetically-Engineered Mouse Core.
These Cores promote innovative, cutting-edge research in digestive diseases. The principal microbes studied by Center investigators are HIV-1, which enters the host through the gastrointestinal and genital tract mucosae; Helicobacter pylori, the most common cause of gastric inflammatory disease; and the commensal bacteria, which play a critical role in the pathogenesis of inflammatory bowel disease.To learn more about the MHIC, click here.