The Vascular Biology and Hypertension Program focuses on molecular and cellular approaches to important problems in cardiovascular medicine. Active in clinical trials include novel therapeutic agents for hypertension, dyslipidemia, diabetes/insulin resistance and obesity.

Program Director
Suzanne Oparil, MD

Related Information

Vascular Biology & Hypertension Fellowship
Vascular Biology & Hypertension Program Website

Types of Research

  • Clinical
  • Translational
  • Basic


Fundamental aspects of hypertension and vascular biology research. Ongoing investigations include assessment of:
  • the role of inflammation in the response to acute vascular injury and its modulation by sex hormones and peptide mimetics of high density lipoprotein (HDL) cholesterol
  • the role of natriuretic peptide signaling and mineralocorticoid receptor antagonism in protecting against adverse remodeling in the pressure-overloaded heart
  • the molecular pathogenesis of hypoxic pulmonary hypertension and pulmonary vascular remodeling
  • novel approaches to the treatment of resistant hypertension and atherosclerotic disease

In addition, the Program is active in clinical trials of novel therapeutic agents for hypertension, dyslipidemia, diabetes/insulin resistance and obesity.


Cellular and molecular approaches to the study of cardiovascular control mechanisms.


  • Anesthesiology
  • Medicine
  • Pathology
  • Physiology & Biophysics
  • Surgery

 Contact Information

Suzanne Oparil, MD

Pam Jacobs, Office Administrator
Email Address: jacobspm@uab.edu

Zeigler Research Building, Room 1034
703 19th Street South
Birmingham, Alabama 35294-0007
Office Phone: (205) 934-2580
Office Fax: (205) 975-5119

For Referring Physicians

Easily refer a patient to UAB through our 24-hour consultation service by phone at (800) UAB-MIST (800) 822-6478 or via email mist@uabmc.edu
If you do not find what you need, feel free to contact one of our Physician Liaisons at (205) 934-6890, or email physicianservices@uabmc.edu.
UAB MIST is for physicians and health professionals only; it should not be used by patients.