Vascular Biology and Hypertension Research Program


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The Vascular Biology and Hypertension Program focuses on molecular and cellular approaches to important problems in cardiovascular medicine. Active in clinical trials include novel therapeutic agents for hypertension, dyslipidemia, diabetes/insulin resistance and obesity.

Program Director
Suzanne Oparil, MD


Related Information

Vascular Biology & Hypertension Fellowship
Vascular Biology & Hypertension Program Website


Types of Research

  • Clinical
  • Translational
  • Basic

Focus

Fundamental aspects of hypertension and vascular biology research. Ongoing investigations include assessment of:
  • the role of inflammation in the response to acute vascular injury and its modulation by sex hormones and peptide mimetics of high density lipoprotein (HDL) cholesterol
  • the role of natriuretic peptide signaling and mineralocorticoid receptor antagonism in protecting against adverse remodeling in the pressure-overloaded heart
  • the molecular pathogenesis of hypoxic pulmonary hypertension and pulmonary vascular remodeling
  • novel approaches to the treatment of resistant hypertension and atherosclerotic disease

In addition, the Program is active in clinical trials of novel therapeutic agents for hypertension, dyslipidemia, diabetes/insulin resistance and obesity.


Methods

Cellular and molecular approaches to the study of cardiovascular control mechanisms.

Collaborations

  • Anesthesiology
  • Medicine
  • Pathology
  • Physiology & Biophysics
  • Surgery

 Contact Information

Suzanne Oparil, MD
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Pam Jacobs, Office Administrator
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Zeigler Research Building, Room 1034
703 19th Street South
Birmingham, Alabama 35294-0007
Office Phone: (205) 934-2580
Office Fax: (205) 975-5119