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Vascular Biology and Hypertension Research Program |
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The Vascular Biology and Hypertension Program focuses on molecular and cellular approaches to important problems in cardiovascular medicine. Active in clinical trials include novel therapeutic agents for hypertension, dyslipidemia, diabetes/insulin resistance and obesity.
Program Director Suzanne Oparil, MD
Related Information Vascular Biology & Hypertension Fellowship Vascular Biology & Hypertension Program Website
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Types of Research
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- Clinical
- Translational
- Basic
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Focus
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Fundamental aspects of hypertension and vascular biology research. Ongoing investigations include assessment of:
- the role of inflammation in the response to acute vascular injury and its modulation by sex hormones and peptide mimetics of high density lipoprotein (HDL) cholesterol
- the role of natriuretic peptide signaling and mineralocorticoid receptor antagonism in protecting against adverse remodeling in the pressure-overloaded heart
- the molecular pathogenesis of hypoxic pulmonary hypertension and pulmonary vascular remodeling
- novel approaches to the treatment of resistant hypertension and atherosclerotic disease
In addition, the Program is active in clinical trials of novel therapeutic agents for hypertension, dyslipidemia, diabetes/insulin resistance and obesity.
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Methods
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Cellular and molecular approaches to the study of cardiovascular control mechanisms. |
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Collaborations
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- Anesthesiology
- Medicine
- Pathology
- Physiology & Biophysics
- Surgery
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Contact Information
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Suzanne Oparil, MD Email Address:
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Pam Jacobs, Office Administrator Email Address:
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Zeigler Research Building, Room 1034 703 19th Street South Birmingham, Alabama 35294-0007 Office Phone: (205) 934-2580 Office Fax: (205) 975-5119
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