Mohammad Athar, Ph.D.
University of Alabama at Birmingham
1530 3RD AVE S
BIRMINGHAM AL 35294-0019
B.Sc. 1975. Chemistry. Lucknow University, Lucknow, India.
M.Sc. 1977. Inorganic Chemistry. Lucknow University, Lucknow, India.
M. Phil. 1978. Coordination Chemistry. Aligarh Muslim University, Aligarh, India.
Ph.D. 1980. Coordination Chemistry. Aligarh Muslim University, Aligarh, India.
|Professor and Vice-Chair for Basic Research:||Department of Dermatology|
|Senior Scientist:||UAB Comprehensive Cancer Center|
|Co-Director:||UAB Skin Disease Research Center|
|Faculty Member:||Graduate School, University of Alabama at Birmingham|
|Adjunct Senior Research Scientist:||Columbia University College of Physicians and Surgeons, NY|
Dr. Athar has a broad background in skin biochemistry, signal transduction, and carcinogenesis. As a visiting research scientist at the Case Western Reserve University, he conducted experiments to show the involvement of oxygen free radicals in the pathogenesis of porphyrin photosensitivity and chemical- and UVB-induced murine skin carcinogenesis and inflammatory responses. Thereafter, his laboratory was involved in developing protocols for preventing environmental carcinogen-induced cancers in various murine models employing a number of synthetic and natural chemopreventive agents including NSAIDs. As a Senior Research Scientist in the Department of Dermatology at Columbia University, New York (as PI or co-PI on several university- and NIH-funded grants), he and his team used various genetic and pharmacological approaches for the chemoprevention of basal cell and squamous cell carcinomas. They showed that the growth of both BCCs and SCCs can be reduced by tazarotene but more effectively by bexarotene. While at UAB, he has been involved in evaluating pharmacological agents that interfere with the hedgehog biochemical pathway. While much of this has relevance for prevention and treatment of basal cell carcinoma, it also contributes in a major way to embryonic development of skin. He has also established a new line of investigation examining signal transduction pathways involved in bister formation employing lewisite as a vesicant. Dr. Athar has a demonstrated record of successful and productive research projects in an area of high relevance for acute cutaneous injury and NMSCs.
For a list of Dr. Athar's publications, visit Pubmed.