Ling Li, PhD, DVM
Ling Li, PhD, DVM
Associate Professor
Dept. of Medicine
Div. of Gerontology, Geriatrics, and Palliative Care
Contact Information:
Office Address: BDB 630
Phone: 934-1889
E-mail: lili@uab.edu
Websites: School of Medicine Faculty Profile
Education:
Yangzhou University, China
BS/DVM, Veterinary Medicine, 1982
Yangzhou University, China
MS, Experimental Medicine, 1986
Iowa State University, Ames, IA
PhD, Molecular, Cellular, and Developmental Biology, 1995
Post-Graduate Training:
Rockefeller University/Mt. Sinai Medical Center, New York, NY
Postdoctoral Fellow, Lipoprotein Metabolism and Atherosclerosis, 1995-6
University of Alabama at Birmingham
Postdoctoral Fellow, Neurobiology of Alzheimer’s disease, 1997-9
Research Interests:
Connections Between Atherosclerosis, Diabetes, and Alzheimer's Disease
Research Description:
Our research program is focused on the genetic and pathophysiological connections between atherosclerosis, diabetes, and Alzheimer’s disease (AD) using transgenic/knockout mouse models. We employ a combination of molecular, cellular, electrophysiological, and behavioral approaches in our research. Current research activities in our laboratory include: 1) Investigation on the role of dietary and/or genetically induced hypercholesterolemia in the development of AD-like neuropathology and behavior in transgenic mouse models of AD; 2) Potential application of cholesterol-lowering drugs such as statins in the prevention and treatment of AD and other age-related dementia; 3) Investigation on the role of sugar-induced obesity and insulin resistance in the development of AD; 4) Investigation on the role of amyloid-beta peptide in atherogenesis; and 5) Studies on structure and function of apolipoprotein A-I, a major protein component of the cardio-protective high-density lipoproteins.
DRC Membership Category:
Senior Scientist