Qin Wang, MD, PhD
Department of Cell, Developmental and Integrative Biology
Beijing Medical University, China
University of Iowa
The long term goal of our research is to reveal novel regulatory pathways controlling G protein-coupled receptors (GPCRs) functions at the molecular and cellular levels and to understand how these regulatory mechanisms influence GPCR-elicited physiological functions in vivo, so as to provide new insights for therapeutic strategies. Current projects include: 1) regulation of alpha2A adrenergic receptor trafficking and signaling in native neurons exploiting gene knockin and knock-out mice; 2) regulation of adenosine-mediated synaptic plasticity and behavior; 3) neuroprotective functions of the alpha2A adrenergic receptor in neurodegenerative diseases.
DRC Membership Category: