Paul W. Sanders, MD, FACP, FAHA
Professor
Dept. of Medicine
Division of Nephrology
Contact Information:
Office Address: LHRB 642
Phone: 205-934-3589
E-mail: psanders@uab.edu
Websites: School of Medicine Faculty Profile
Education:
University of Alabama in Huntsville
BS, Chemistry, 1975
University of South Alabama College of Medicine, Mobile, AL
MD, 1979
Post-Graduate Training:
University of Alabama Hospital, Birmingham, AL
Intern, Internal Medicine, 1979-80
University of Alabama Hospital, Birmingham, AL
Resident, Internal Medicine, 1980-2
University of Alabama at Birmingham School of Medicine, Birmingham, AL
Fellow, Nephrology Research & Training Center, 1982-5
Research Interests:
Mechanisms of progressive renal injury, related to:
- Monoclonal immunoglobulin light chain-related renal diseases, including acute kidney injury, cast nephropathy, monoclonal light chain-related glomerulopathy and amyloidosis, type AL
- Hypertensive nephrosclerosis
- Chronic allograft nephropathy
- Proteinuria
Dietary salt and salt-sensitive hypertension
Transforming growth factor-ß
Nitric oxide-dependent signaling and reactive nitrogen species
Acute kidney injury and repair
Research Description:
Paul W. Sanders, M.D., is a translational researcher interested in the pathogenesis of salt-sensitive hypertension and hypertensive nephrosclerosis as well as the mechanism of kidney damage from immunoglobulin light chains. Ongoing research includes: 1) the role of endothelial Pyk2 and c-Src in signaling induced by salt ingestion; 2) the mechanism of intravascular production of TGF-ß1; 3) the mechanism by which light chain-induced oxidative stress activates c-Src in renal epithelium.
DRC Membership Category:
Affiliate