Dept. of Medicine

Division of Nephrology

Contact Information:

Office Address: TH 611L
Phone: 205-996-9641 
Websites: UAB SOM Faculty Profile


Christian Medical College, Ludhiana, India

MBBS, 1990

Post-Graduate Training:

Post-Graduate Institute, Chandigarh, India

Resident, Internal Medicine, 1991-4

Newton Wellesley Hospital, Newton, MA

Resident, Internal Medicine, 1994-6

Boston University Medical Center, Boston, MA

Research Fellowship, Nephrology, 1996-9

Research Description:

Over the past decade, Dr. Chugh's laboratory has focused on investigating mechanisms of proteinuria, with the intent of developing mechanism based therapy. Some of the projects include identifying a molecular basis for slit diaphragm permeability (JCI 2003), identification and characterization of the role of ZHX transcriptional factors in podocyte gene expression (JBC 2006), identification of glucocorticoid-sensitive genes in the podocyte (KI 2007), dissecting changes in podocyte gene expression during the development of glomerular capillary loop collapse (KI 2007), and identification of podocyte secreted proteins that induce proteinuria in Minimal Change Disease and other forms of nephrotic syndrome (Nature Medicine 2010). Current therapeutic strategies under development are based on the manipulation of podocyte expression of ZHX transcriptional factors and studies on the sialylation of Angiopoietin-like-4.  


DRC Membership Category:

Senior Scientist