MIC Program


SCHEDULE

2014 MIC MEETING at the University of Alabama at Birmingham

Wednesday, May 21, 2014


12:00 - 2:00 pm Arrivals, Registration and Lunch.

2:00 - 2:15 pm Welcome and Introduction: Anath Shalev and Meredith Preuss (hosts)

2:15 - 3:30 pm ORAL SESSION-1 – Developing, Regenerating & Growing New Islets – in vivo or in test tubo
          (Moderator: Carmella Evans-Molina)

2:15 - 2:30 pm Corentin Cras-Méneur - Active Notch signaling controls the maintenance of the fate of the Ngn3 Progenitors through RBP-Jkappa in the developing pancreas
2:30 - 2:45 pm Iljana Gaffar - A Potential Therapeutic Role for MafA through Ectopic Expression in Pancreatic Ducts
2:45 - 3:00 pm
Michael Lawrence
- Differentiation of Pancreas-Derived Mesenchymal Stem Cells into Hormone-Producing Islet-Like Cell Clusters
3:00 - 3:15 pm
John Wiersch - No Evidence for Bone Marrow Derived Stem Cell Contribution to Pancreatic Regeneration in a Mouse Parabiosis Model
3:15 - 3:30 am
Gina M.Coudriet – Maturation Defects in NOD Macrophages Impacts Beta Cell Regeneration

3:30 - 4:00 pm Coffe/Tea Break

4:00 - 5:15 pm SESSION-2 Modes and Maladies of Gene Regulation in Islets
          (Moderator: Raghu Mirmira)

4:00 - 4:15 pm Brian McKenna - Identification and Characterization of Pdx1 Coregulators
4:15 - 4:30 pm Justin S. Johnson - Pancreatic and Duodenal Homeobox Protein 1 Enhances Transcription of Sarcoendoplasmic Reticulum Calcium ATPase 2 in the Beta Cell
4:30 - 4:45 pm
Chad S. Hunter - Ldb1-mediated transcriptional complexes during ß-cell development and function
4:45 - 5:00 pm
KyungHee Hong - IL-1beta Regulates Beta-cell TXNIP Expression
5:00 - 5:15 pm
Caitlin Orr - Identification of Tissue Specific Enhancer Elements in the Pancreatic Alpha Cell

5:15 - 6:00 pm Break

6:00 - 7:30 pm Dinner

7:30 - 9:30 pm POSTER SESSION and SOCIAL

Thursday, May 22, 2014

8:00 - 9:00 am Breakfast

9:00 - 10:15 am SESSION-3 – Islet Factors, Functions and Metabolic Signals
          (Moderator: Roland Stein)

9:00 - 9:15 am Amelia K. Linnemann - Cholecystokinin is Directly Regulated by cAMP in Beta Cells
9:15 - 9:30 am Matthew J. Merrins - Phase Analysis of the Beta Cell Triggering Pathway Reveals Unexpected Feedback on Oscillatory Metabolism
9:30 - 9:45 am
Kayla A. Boortz - G6PC2 Evolved to Modulate Insulin Secretion in Response to Stress
9:45 - 10:00 am Weiwei Xu - Androgen Receptor-Dependent Transcriptome Analysis in Pancreatic Beta Cells: Implications for Type 2 Diabetes Risk in Aging Men
10:00 - 10:15 am
Ben A. Hall - Insulin-resistance and Decreased Beta-cell Mass in Beta-cell–specific IRS-2 Knockout Mice

10:15 - 10:45 am Coffee Break

10:45 - 12:00 pm SESSION-4 Oxidative and Inflammatory Stressing on Islets
          (Moderator: John Corbett)

10:45 - 11:00 am Ashley R. Burg - Superoxide Deficiency Hinders Anti-Viral Responses ofNon-Obese Diabetic Macrophages during Diabetogenic Coxsackie B4 Virus Infection
11:00 - 11:15 am
Katarzyna Broniowska - Location, Location, Location! It Is a Key Determinant in the Biological Actions of Free Radicals on Beta Cells
11:15 - 11:30 am Ting Zhang - FoxO1 Protects Beta-Cell against Oxidative Stress
11:30 - 11:45 am Bryndon J. Oleson - DNA Damage-Mediated Activation of ATM as a Trigger for Cytokine-Induced Apoptosis
11:45 - 12:00 pm Emily K. Anderson-Baucum - The Role of Macrophage Deoxyhypusine Synthase in the Progression of Obesity-Associated Metabolic Inflammation

12:00 - 1:30 pm Lunch

1:30 - 2:45 pm SESSION-5 – Potential Means of Fixing Type-1 Diabetes
          (Moderator: Les Satin)

1:30 - 1:45 pm Zunaira Z. Chaudhry - The Proinsulin/C-peptide Ratio and HSP90: Potential Biomarkers for Early Detection of Type 1 Diabetes
1:45 - 2:00 pm J. Stewart New - Modulation of Autoimmune Diabetes By Innate-Like B Cell Derived Antibodies Against N-Acetyl Glucosamine
2:00 - 2:15 pm
Robert N. Bone - Fluoroketone-based Inhibition of the Ca2+-independent PhospholipaseA2beta in Neonates Reduces Incidence of Type 1 Diabetes
2:15 - 2:30 pm
Lindsey E. Padgett - NADPH Oxidase-Deficient Macrophages Display a Dampened M1 Macrophage Phenotype in Type 1 Diabetes
2.30 - 2.45 pm
Stephen Harrington - Allogeneic Islet Transplantation by Encapsulation in Bio-inspired Hydrogel: the Importance of Scaffold Geometry

2:45 - 3:15 pm Coffee/Tea Break

3:15 - 4:30 pm SESSION-6 – Pathogenesis and Potential Means of Fixing Type-2 Diabetes
          (Moderator: Colin Nichols)

3:15 - 3:30 pm Mieke Baan - FoxM1 Overexpression in Pancreatic Beta Cells Increases Pancreatic Insulin Content and Lowers Plasma Glucose
3:30 - 3.45 pm Gu Jing - TXNIP induces IAPP expression via miRNA-124a and FOXA2
3:45 - 4:00 pm
Damien Demozay - Ablation of FoxO3a, but not FoxO1, specifically in beta-cells causes beta-cells failure in mice exposed to a high calorie diet
4:00 - 4:15 pm
Holly A. Cyphert - Characterization of Human MafA/B Activity in Pancreatic Beta Cells
4:15 - 4:30 pm Johanne H. Ellenbroek - Long-term Ketogenic Diet Causes Glucose Intolerance and Reduced Beta and Alpha-Cell Mass but No Weight Loss in Mice

4:30 - 4:45 pm Break


4:45 - 5:45 PM SESSION-7 THE 7th ANNUAL LACY MEDAL LECTURE
          (Moderator: CHRISTOPHER RHODES)

          Geoffrey G. W. Sharp, Ph.D. (Cornell University) - ‘From the Artic to Bangladesh to the Islet’

6:00 - 8:00 pm Awards Banquet

8:00 - 10:00 pm Poster Mingling and Entertainment

Friday, May 24, 2013

9:00 am - 12:00 pm Departures

Immediately following, the Midwest Islet Club Meeting, The UAB Comprehensive Diabetes Center will be holding their annual UAB Diabetes Research Day.
For more information, click here.