Hsh phdDr. Hui-Chen Hsu is Associate Professor of Medicine in the Division of Clinical Immunology and Rheumatology. Dr. Hsu collaborated with Drs. John D. Mountz, Hao Li, Jun Li, Yong Zhou, David Crossman, Janusz H. Kabarowski and several other leading investigators in the field and made the seminal discovery on a novel pathogenic role of type I interferon (IFN) in promoting systemic lupus erythematosus (SLE), a challenging autoimmune disease without a cure. The work stemmed from Dr. Hsu’s research which focuses on how elevated type I IFNs produced by plasmacytoid dendritic cells (pDCs) in the spleen marginal zone can induce follicular translocation of marginal zone (MZ) B cells.