Dr. Xiaoli Li & Dr. Julie Baskin's paper entitled "The Unique Cytoplasmic Domain of Human FcγRIIIA Regulates Receptor-Mediated Function", published in the Journal of Immunology has been selected as the Department's paper of the month for November 2012.
Dr. Xiaoli Li obtained a diploma in Biochemistry and a Master’s in virology both from Wuhan University, China. In 1992 he obtained a Ph.D. in Immunology from UAB. After a postdoctoral fellowship at Cleveland Clinic Foundation and a year as Instructor at Rush Medical Center, he returned to UAB where he joined Dr. Kimberly’s group. He is currently Assistant Professor in the Division of Clinical Immunology and Rheumatology.
Dr. Li's current work combines the use of functional genomic analysis and high content multi-chromatic flow cytometry analyses to understand the effects of natural gene polymorphisms of FcγR genes, their unique regulation, and the associated down-stream signaling events in SLE autoimmunity.
Dr. Baskin received a B.S. in Zoology from the University of Massachusetts at Amherst in 1980, her M.S. in Biology from Georgetown University in 1982, and her Ph.D. in Cell and Molecular Biology from the University of Alabama at Birmingham in 1991. She was awarded an Immunologic Diseases and Basic Immunology Training Grant fellowship and joined the laboratory of Dr. Ed Lamon where she investigated idiotypic network activation to the hapten 2, 4 dinitrophenyl (DNP) and antibody-induced inhibition of sarcoma growth using monoclonal antibodies specific for Moloney murine sarcoma/leukemia cell surface antigen. More recently, Dr. Baskin worked in the laboratory of Dr. Robert Kimberly where she had been investigating the role of protein kinase C (PKC) phosphorylation of the alpha-chain cytoplasmic domains of gamma-chain associated Fc receptors. Research interests include receptor-initiated cell signalling and the contribution of the α-chain cytoplasmic domain to downstream cellular responses.
Dr. Wells received a B.S. in genetics from Texas A&M University in 2000 and his M.D. from the University of Texas Health Science Center in Houston in 2005. He completed his Internship and Residency in Internal Medicine in 2008, served as Chief Medical Resident from 2008-2009 and completed his fellowship in Pulmonary, Allergy, and Critical Care in 2012, all at UAB. He was the first UAB pulmonary fellow selected for the NIH sponsored T32 training grant in Lung Biology and Translational Medicine for 2010-2012 and he is the 2012 recipient of the Walter B. Frommeyer, Jr. Fellowship in Investigational Medicine. Dr. Wells joined the laboratory of Dr. Edwin Blalock in 2010, where he has been investigating the role of neutrophilic inflammation in the pathogenesis of chronic obstructive pulmonary disease (COPD) using proteomics, synthetic chemistry, and murine models. In July 2012 he joined the Division of Pulmonary, Allergy, and Critical Care as an Assitant Professor. His research interest is in COPD, particularly in the areas of pathogenesis, biomarker discovery, disease progression, and treatment.
Dr. Christine Sestero’s paper entitled “CD5-Dependent CK2 Activation Pathway Regulates Threshold for T Cell Anergy”, published in the Journal of Immunology has been selected as the Department of Medicine’s September 2012 Paper of the Month.
Dr. Sestero conducted her postdoctoral fellowship at UAB under the mentorship of Chander Raman in the Division of Clinical Immunology and Rheumatology. She received her B.S. in Biology from The College of Idaho and her Ph.D. in Microbiology from Idaho State University. During her time as a postdoc, Dr. Sestero was a recipient of NIH Postdoctoral Scholar Training Grants in Immunology and Rheumatology and the NIH/NIGMS IRACDA Award for the Mentored Experiences in Research, Instruction, and Teaching (MERIT) Program. She will continue her research collaborations with Dr. Raman in her new appointment as Assistant Professor of Biology at the University of Montevallo.
Dr. Hong Li is currently a research associate in Dr. Yabing Chen’s lab in the Department of Molecular & Cellular Pathology. Dr. Li received her MS degree from Wuhan University and her PhD from Central South University in China. She completed her postdoctoral fellowship at UAB under the mentorship of Dr. Guangjie (Jeff) Cheng in the Division of Pulmonary, Allergy, and Critical Care Medicine.