Welner RobRank:                    
Assistant Professor

Division:
               
Hematology & Oncology

Campus Address:
WTI 510D

Mailing Address:  
1720 2nd Avenue South, WTI 510D
Birmingham, AL 35294-3300

Phone:                   
(205) 934-0439


Departmental Affiliation(s):
Primary: Medicine, Hematology/Oncology


EDUCATION             

 
Graduate School
University of Oklahomas Health Sciences Center, PhD Immunology/Microbiology

Fellowship
Harvard Medical School, Postdoc Fellowship

PROFESSIONAL SOCIETIES
American Society of Hematology (ASH)
American Association of Immunologists

BIOGRAPHICAL SKETCH
I received my PhD degree in Immunology and Microbiology from University of Oklahoma with Dr. Paul Kincade. I later moved to the Beth Israel Deaconess Medical Center/Harvard Medical School for my post-doctoral training with Dr. Daniel Tenen.

RESEARCH/CLINICAL INTERESTS
Altered hematopoietic environment in leukemia.
My research has focused on stem cell biology, transcription factors, and gene regulation differences between normal adult cells and their diseased counterpart. Major advances have been made recently in describing the transcriptional networks dictating self-renewal of stem cells, and a number of important transcriptional regulators have been characterized during hematopoiesis; meanwhile, understanding how these processes become dysregulated in their function in hematopoietic stem cells has not been well established. My research projects investigate the role of steady-state and perturbed microenvironments on the stem cell self-renewal and differentiation, and more importantly the interplay between these contradictory forces within the stem cell niche.

SELECTED PUBLICATIONS
Treatment of chronic myelogenous leukemia by blocking cytokine alterations found in normal stem and progenitor cells.
Welner RS, Amabile G, Bararia D, Czibere A, Yang H, Zhang H, Pontes LL, Ye M, Levantini E, Di Ruscio A, Martinelli G, Tenen DG. Cancer Cell. 2015 May 11;27(5):671-81.

Publications: See a listing of publications on PubMed , a service of the National Library of Medicine.