Saag Michael S. Saag, MD


Medical School: University of Louisville
Residency: Internal Medicine, UAB
Fellowship: Infectious Diseases, UAB


Dr. Saag is Professor of Medicine and Director of the UAB Center for AIDS Research. During his fellowship in Infectious Diseases, Dr. Saag conceived the concept of a comprehensive HIV outpatient (1917) clinic dedicated to the provision of comprehensive patient care in conjunction with the conduct of high quality clinic trials, basic science, and clinical outcomes research. Over the last 25 years, the clinic has treated more than 9000 patients and has become recognized as one of the best sites for clinical research and care in the United States. Dr. Saag has published over 300 articles in peer reviewed journals, including the first description of the use of viral load in clinical practice (Science, 1993), the first description of the rapid dynamics of viral replication (Nature, 1995), the first guidelines for use of viral load in practice (Nature Medicine, 1996), the first proof of concept of fusion inhibition as a therapeutic option (Nature Medicine, 1998), and directed the ‘first-in- patient’ studies of 7 of the 25 antiretroviral drugs currently on the market (including indinavir, efavirenz, abacavir, and enfuvirtide). Dr. Saag has received the Myrtle Wreath Award from Hadassah, was listed as one of the top ten cited HIV researchers by Science (1996), and received two Argus Awards in 2009 for Best Lectures to the 1st year medical students at UAB and another Argus Award in 2010 and 2011. In December 2010, he was awarded the President’s Medal of UAB, the highest honor given at this institution. In 2014, Dr. Saag was named the Castle-Connolly National Physician of the Year Award for Clinical Excellence. Dr. Saag just finished a memoir entitled, “Positive: One doctor’s encounters with death, life, and the US Healthcare System,” which was released in the April 2014.


Mike Saag, MD (Infectious Diseases) won the 2016 Ernest Cotlove Award from the Academy of Clinical Laboratory Physicians and Scientists for outstanding contributions to the science of laboratory medicine

UAB Medicine Physicians Profile