Neurology

Director

Robert Knowlton, M.D.

The nationally-ranked UAB Department of Neurology is currently home to eight comprehensive divisions and seven centers offering an array of clinical activities. Over 25,000 patients are cared for annually through state-of-the-art subspecialty care and innovative treatments. Our residents have the opportunity to work in various neurology fields with 50 clinical and research faculty members.

Expertise

The UAB Neurology facility offers expertise and assistance in the following research capabilities:

• Intracranial electrocorticography (ECoG) recordings with grid and depth electrodes from human brain–one of the largest epilepsy neocortial epilepsy surgery programs in the country.
• Intraoperative electrocortical stimulation brain mapping–cortical and subcortical
• Novel MRI pulse sequence development, essentially all of which has come from Dr. Don Twieg’s (biomedical engineering) and people he has trained. His PARSE technique is revolutionary and could fuel research for years to come if we capitalize on it.

Hardware

• Magetoencephalography / Magnetic Source Imaging Laboratory–research and clinical human brain mapping (cortical function and associate tractography).
• Boshell MRI–clinical fMRI-based human brain mapping (hardware pending transfer from purchase associated with North Pavilion MRI scanners).

Software and Technology

• Curry 6– integrates multiple complementary functional and image modalities (EEG, ECoG, MEG; MRI, fMRI, PET, SPECT and CT) in a single software package for the purpose of obtaining the maximum accuracy of electrical source analysis.
• Ictal SPECT based SPM analysis package with age matched normal.
• Analyze 7