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Program in Immunology

The multi-disciplinary Program in Immunology consists of over 100 faculty who identify themselves as basic or clinical immunologists and are members of multiple units at UAB.

UAB is the home of internationally prominent research programs. Newer programs in Cancer Immunology, Allergy, Immunogenetics, Inflammation and Tissue Injury, Transplantation Immunology, Neuroimmunology, and Basic Immunology of the T cell and innate systems are poised to become highly competitive.

A brief history of the Program in Immunology at UAB, written by Dr. Claude Bennett

Memory B cell marker predicts long-lived antibody response to flu vaccine

Study by Anoma Nellore, M.D., Fran Lund, Ph.D., and colleagues.

Read more: Memory B cell marker Opens an external link.

UAB researchers and clinicians are developing and testing new and improved vaccines

For diseases from influenza to HIV to COVID.

Past, Present, and Future of Vaccines Opens an external link.

Inventions that flowed from basic bacterial research have led faculty to be named senior members of the National Academy of Inventors.

Michael Niederweis, Ph.D., and Moon Nahm, M.D.

Two UAB faculty named Senior Members by the National Academy of Inventors Opens an external link.

Beatriz Leon-Ruiz, Ph.D.

In a study published in the Nature Journal Cellular & Molecular Immunology, Beatriz Leon-Ruiz, PhD and colleagues report an unrecognized mechanism of how interrupted IL-6 signaling creates Th2 bias, as well as the specific role of IL-6 signaling in that process.

How interleukin-6 helps prevent allergic asthma and atopy by suppressing interleukin-2 signaling

Jianmei Leavenworth, M.D., Ph.D.

The American Association of Immunologists (AAI), in partnership with eBioscience, Inc., recently announced that Jianmei Leavenworth, M.D., Ph.D, associate professor in the UAB Department of Neurosurgery, is the recipient of the 2023 Lustgarten-Thermo Fisher Scientific Memorial Award.

Leavenworth receives 2023 Lustgarten-Thermo Fisher Scientific Memorial Award

Tanecia Mitchell, Ph.D.

Tanecia Mitchell, Ph.D., Assistant Professor with the University of Alabama at Birmingham Department of Urology, has been awarded an $2.7 million R01 grant to investigate the role of dietary oxalate on immune function in kidney stone disease.

Mitchell awarded $2.7 million R01 grant for kidney stone disease research

by J. Claude Bennett

I became Chair of the Department of Microbiology and Director of the Bennett1976Division of Rheumatology in 1970. Although resources were meager Cooper and I jointly worked to recruit students, fellows and new faculty to UAB. The decade of 1970-1980 was a time of great excitement for the immunology program. Perhaps the most important element in our programmatic development was the formation of a Microbiology Advisory Committee – made up of senior people from outside UAB. The immunologists on the committee were Ray D. Owen, Ph.D. – Chair of the Biology Division at CalTech; Henry Kunkel. M.D. – Professor at the Rockefeller Institute (now University); and Herman Eisen, M.D., Professor of Microbiology at Washington University and later at M.I.T. These men gave us advice on how to develop programs within a department and to build relationships across other elements of the University. In addition they helped in recruitment of new young faculty and pointed students at their institutions to UAB for postdoctoral fellowships.

The Department of Microbiology was fortunate in the recruitment of Roy RoyCurtisCurtiss III, Ph.D., from the Oak Ridge National Laboratory in 1971. Professor Curtiss’s field was bacterial genetics, and he developed an excellent group around him. Most important for the history of immunology is that by 1975 he had established the Molecular Cell Biology Graduate Program which became the center for training graduate students in all the basic science disciplines at UAB. Many of these “early” students in the program were directed to immunology because of the strength of its faculty.

Max Cooper’s program in Pediatrics developed rapidly (1966-1968) with the early JohnKearneyrecruitment of Sandy Lawton, M.D., to work in the immunodeficiency area, and Richard Johnston, M.D., to work with macrophages and complement. Both of these men were appointed to professorships in Pediatrics at other universities: Lawton to Vanderbilt and Johnston to the University of Pennsylvania. In the mid-to-late 1970’s, John Kearney, Ph.D., and Hiromi Kubagawa, M.D., joined the Cooper lab. A host of graduate students, postdocs, and distinguished visitors followed. This was the major contributing factor to the growth, visibility, excellence and prestige of the UAB Immunology Program.

 

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