Selvarangan Ponnazhagan, PhD - Selected Recent Publications in Peer Reviewed Journals

 


Sawant A, Schafer CC, Ponnazhagan S, Deshane JS. 2014. The dual targeting of immunosuppressive cells and oxidants promotes effector and memory T-cell functions against lung cancer. Oncoimmunology. 3(1):e27401. PMID: 24711958 PMCID: PMC3976979


Sawant A, Schafer CC, Jin TH, Zmijewski J, Tse HM, Roth J, Sun Z, Siegal GP, Thannickal VJ, Grant SC, Ponnazhagan S, Deshane JS. 2013. Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways. Cancer Res. 73(22):6609-20. PMID: 24085788 PMCID: PMC3854493


Sawant A, Ponnazhagan S. 2013. Myeloid-derived suppressor cells as osteoclast progenitors: a novel target for controlling osteolytic bone metastasis. Cancer Res. 73(15):4606-10. PMID: 23887974 PMCID: PMC3732563


Sawant A, Ponnazhagan S. 2013 Myeloid-derived suppressor cells as a novel target for the control of osteolytic bone disease. Oncoimmunology. 2(5):e24064. PMID: 23762794 PMCID: PMC3667900


Sawant A, Ponnazhagan S. 2013. Role of plasmacytoid dendritic cells in breast cancer bone dissemination. Oncoimmunology. 2(2):e22983. PMID: 23526329 PMCID: PMC3601166


Sawant A, Hensel JA, Chanda D, Harris BA, Siegal GP, Maheshwari A, Ponnazhagan S. 2012. Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells. J Immunol. 189(9):4258-65. PMID: 23018462 PMCID: PMC3531993


Sawant A, Chanda D, Isayeva T, Tsuladze G, Garvey WT, Ponnazhagan S. 2012. Noggin is novel inducer of mesenchymal stem cell adipogenesis: implications for bone health and obesity. J Biol Chem. 287(15):12241-9. PMID: 22351751 PMCID: PMC3320975


Kumar S, Ponnazhagan S. 2012. Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect. Bone. 50(4):1012-8. PMID: 22342795 PMCID: PMC3339043


Yang SW, Chanda D, Cody JJ, Rivera AA, Waehler R, Siegal GP, Douglas JT, Ponnazhagan S. 2011. Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancer. PLoS One. 6(10):e25131. PMID: 22022379 PMCID: PMC3192051


Hensel JA, Chanda D, Kumar S, Sawant A, Grizzle WE, Siegal GP, Ponnazhagan S. 2010. LL-37 as a therapeutic target for late stage prostate cancer.  71(6):659-70. PMID: 20957672


Triozzi PL, Aldrich W, Ponnazhagan S. 2010. Regulation of the activity of an adeno-associated virus vector cancer vaccine administered with synthetic Toll-like receptor agonists. Vaccine. 28(50):7837-43. PMID: 20937315


Lee JH, Moore LD, Kumar S, Pritchard DG, Ponnazhagan S, Deivanayagam C. 2010. Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells. Cancer Lett. 298(2):238-49. PMID: 20688428


Andea AA, Patel R, Ponnazhagan S, Kumar S, DeVilliers P, Jhala D, Eltoum IE, Siegal GP. 2010. Merkel cell carcinoma: correlation of KIT expression with survival and evaluation of KIT gene mutational status. Hum Pathol. 41(10):1405-12. PMID: 20594584


Chanda D, Kumar S, Ponnazhagan S. 2010 Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in diseases of the skeleton. J Cell Biochem. 111(2):249-57. PMID: 20506559


Kumar S, Wan C, Ramaswamy G, Clemens TL, Ponnazhagan S. 2010. Mesenchymal Stem Cells Expressing Osteogenic and Angiogenic Factors Synergistically Enhance Bone Formation in a Mouse Model of Segmental Bone Defect. Mol Ther. PMID: 20068549


Kumar S, Nagy TR, Ponnazhagan S. 2010. Therapeutic potential of genetically modified adult stem cells for osteopenia. Gene Ther. 17(1):105-16. PMID: 19741731


Chanda D, Isayeva T, Kumar S, Hensel JA, Sawant A, Ramaswamy G, Siegal GP, Beatty MS, Ponnazhagan S. 2009. Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in prostate cancer bone metastasis. Clin Cancer Res. 15(23):7175-85. PMID: 19920103


Byon CH, Hardy RW, Ren C, Ponnazhagan S, Welch DR, McDonald JM, Chen Y 2009. Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4. Lab Invest. 89(11):1221-8. PMID: 19752858


Westbrook L, Ramanathan HN, Isayeva T, Mittal AR, Qu Z, Johnson MD, Kern FG, Ponnazhagan S, Grubbs CJ, Thottassery JV. 2009. High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1. Int J Oncol. 34(5):1425-31. PMID: 19360356


Isayeva T, Moore LD, Chanda D, Chen D, Ponnazhagan S. 2009. Tumoristatic effects of endostatin in prostate cancer is dependent on androgen receptor status. Prostate. 69(10):1055-66. PMID: 19301304


Zhang J, Luo B, Tang L, Wang Y, Stockard CR, Kadish I, Van Groen T, Grizzle WE, Ponnazhagan S, Fallon MB. 2009. Pulmonary angiogenesis in a rat model of hepatopulmonary syndrome. Gastroenterology. 136(3):1070-80. PMID: 19109954


White AF, Mazur M, Sorscher EJ, Zinn KR, Ponnazhagan S. 2008. Genetic modification of adeno-associated viral vector type 2 capsid enhances gene transfer efficiency in polarized human airway epithelial cells. Hum Gene Ther. 19(12):1407-14. PMID: 18778196