Selvarangan Ponnazhagan, PhD - Selected Recent Publications in Peer Reviewed Journals

Hensel JA, Chanda D, Kumar S, Sawant A, Grizzle WE, Siegal GP, Ponnazhagan S. 2010. LL-37 as a therapeutic target for late stage prostate cancer.  71(6):659-70. PMID: 20957672

Triozzi PL, Aldrich W, Ponnazhagan S. 2010. Regulation of the activity of an adeno-associated virus vector cancer vaccine administered with synthetic Toll-like receptor agonists. Vaccine. 28(50):7837-43. PMID: 20937315

Lee JH, Moore LD, Kumar S, Pritchard DG, Ponnazhagan S, Deivanayagam C. 2010. Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells. Cancer Lett. 298(2):238-49. PMID: 20688428

Andea AA, Patel R, Ponnazhagan S, Kumar S, DeVilliers P, Jhala D, Eltoum IE, Siegal GP. 2010. Merkel cell carcinoma: correlation of KIT expression with survival and evaluation of KIT gene mutational status. Hum Pathol. 41(10):1405-12. PMID: 20594584

Chanda D, Kumar S, Ponnazhagan S. 2010 Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in diseases of the skeleton. J Cell Biochem. 111(2):249-57. PMID: 20506559

Kumar S, Wan C, Ramaswamy G, Clemens TL, Ponnazhagan S. 2010. Mesenchymal Stem Cells Expressing Osteogenic and Angiogenic Factors Synergistically Enhance Bone Formation in a Mouse Model of Segmental Bone Defect. Mol Ther. PMID: 20068549

Kumar S, Nagy TR, Ponnazhagan S. 2010. Therapeutic potential of genetically modified adult stem cells for osteopenia. Gene Ther. 17(1):105-16. PMID: 19741731

Chanda D, Isayeva T, Kumar S, Hensel JA, Sawant A, Ramaswamy G, Siegal GP, Beatty MS, Ponnazhagan S. 2009. Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in prostate cancer bone metastasis. Clin Cancer Res. 15(23):7175-85. PMID: 19920103

Byon CH, Hardy RW, Ren C, Ponnazhagan S, Welch DR, McDonald JM, Chen Y 2009. Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4. Lab Invest. 89(11):1221-8. PMID: 19752858

Westbrook L, Ramanathan HN, Isayeva T, Mittal AR, Qu Z, Johnson MD, Kern FG, Ponnazhagan S, Grubbs CJ, Thottassery JV. 2009. High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1. Int J Oncol. 34(5):1425-31. PMID: 19360356

Isayeva T, Moore LD, Chanda D, Chen D, Ponnazhagan S. 2009. Tumoristatic effects of endostatin in prostate cancer is dependent on androgen receptor status. Prostate. 69(10):1055-66. PMID: 19301304

Zhang J, Luo B, Tang L, Wang Y, Stockard CR, Kadish I, Van Groen T, Grizzle WE, Ponnazhagan S, Fallon MB. 2009. Pulmonary angiogenesis in a rat model of hepatopulmonary syndrome. Gastroenterology. 136(3):1070-80. PMID: 19109954

White AF, Mazur M, Sorscher EJ, Zinn KR, Ponnazhagan S. 2008. Genetic modification of adeno-associated viral vector type 2 capsid enhances gene transfer efficiency in polarized human airway epithelial cells. Hum Gene Ther. 19(12):1407-14. PMID: 18778196