Microbiology News

Stealth pig cells may hold the key to treating diabetes in humans

harry shroederUniversity of Alabama at Birmingham researchers are exploring ways to wrap pig tissue with a protective coating to ultimately fight diabetes in humans. The nano-thin bilayers of protective material are meant to deter or prevent immune rejection.

The ultimate goal: transplant insulin-producing cell-clusters from pigs into humans to treat Type 1 diabetes.
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UAB Biomarker beats gold standard in detecting brain shunt infections

harry shroederIn a study of children with brain shunts at Children’s of Alabama, a University of Alabama at Birmingham investigational biomarker outperformed the current “gold standard” test for detecting bacterial infections in the shunts.
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Micro researchers involved in studies reporting a new quality-control checkpoint in developing B cells that may affect vaccine responses.

harry shroederMicro researchers involved in studies reporting a new quality-control checkpoint in developing B cells that may affect vaccine responses.




Checkpoint in B cell development discovered with possible implications on vaccine potency

Teaching metabolomics: a UAB outreach to researchers in sub-Saharan Africa


Janusz Kabarowski, Ph.D, is playing an important role in a metabolomics initiative.


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NFL Charities has awarded UAB a $100,000 grant to study a compound that could minimize the effects of concussions. Known as catalytic oxidoreductant, the compound may interrupt a cascade of biochemical injuries, including oxidative stress and an aggressive immune response to brain inflammation, that cause a large amount of additional cell death after a concussion’s initial damage to brain cells. Candace Floyd, Ph.D., research director in the Department of Physical Medicine and Rehabilitation, and Hubert Tse, Ph.D., an assistant professor in the Department of Microbiology who helped to develop the compound, will lead the research team. Additional studies will examine the compound’s effects on multiple concussions; evidence suggests three or more lead to significant brain damage. The results could point to a drug that could be administered immediately after a concussion, anywhere from sidelines to battlefields.
Winter 2013 UAB Medicine