“UAB, industry partnership could lead to first rapid test for bacterial meningitis,” by Nicole Wyatt. UAB School of Medicine News, January 21, 2015.
"This simple meningitis test could save money and lives—and open a new window on inflammation," by Matt Windsor. The Mix, January 23, 2015.
FIRST PLACE ($4000 funding + $250 prize)
A novel approach to generate HIV-1 broadly neutralizing antibodies
Team: Jan Novak, Zina Moldoveanu, Hui Hu, Matthew Renfro, Jialan Geng, Hairong Wei, Bi Shi, Qing Wei, Milan Raska, Audra Laube, Bara Knoppova
SECOND PLACE ($2000 funding + $125 prize)
Novel copper-coordinating small molecule inhibitors against methicillin resistant stphylococcus aureus
Team: Suzanne Michalek, Olaf Kutsch, Frank Wolschendorf, Santosh Shah, Alex Dalecki, Kaitlyn Schaaf
PEOPLE'S CHOICE ($1000 funding + $75 prize)
Engineer the CRISPR/Cas9 system to clear pathogenic DNA virus infections in AIDS patients
Team: George Luo, Mengxi Jiang, Joshua Justice
*SPECIAL GLOBAL HEALTH AWARD ($4000 funding + $250 prize)
Isolation of human antibodies for the treatment of fungal infections
Team: John Kearney, Rodney Glenn King, Emily Stefanov
As an undergraduate chemistry major in the 1990s, Greer spent a summer doing biomedical research in Justement’s lab at the University of Texas Medical Branch at Galveston. This initial encounter led Greer to choose a career in research. She is currently associate professor of biology at Georgia State University, specializing in transcriptional and epigenetic regulation of immune response and cancer immunology.
Justement, who chairs the Training and Career Opportunities Subcommittee of the Federation for American Societies for Experimental Biology, continues to change the lives of students here at UAB.
Read Susanna Greer’s thoughts about mentoring in “Making Mentoring Meaningful.”
An October 2014 US Airways article, “UAB: A Center for Healing,” features the UAB Comprehensive Cancer Center and is illustrated with a photograph of UAB Microbiology Department professor Christopher Klug, Ph.D.
The lab of Allan Zajac, Ph.D., associate professor of microbiology at UAB, is looking at CD8 T cells, which can develop into the classic “killer” T cells that can destroy virus-infected cells. A cell-surface adhesion molecule called ICAM seems to direct the type of T cell produced after cell-to-cell interactions — some of the CD8 T cells become killer T cells, and others become long-lived memory T cells. Zajac believes that ICAM limits the amount of IL-2 experienced by some clustered T cells, and this helps produce memory cells rather than killer cells. Zajac has two versions of lymphocytic choriomeningitis virus that differ by only two nucleotides — one causes an acute infection in mice that is quelled in 10 days, while the other, faster-replicating virus gets out of control and exhausts the immune system, and the mice take months to recover.
Click here for the rest of the story -- “$10 million UAB grant is probing control of viral infections”