Matalon, Sadis, PhD
Department of Anesthesiology
BMR2 224, -2172

Understand the basic mechanisms and elucidate the physiological consequences of reactive oxygen-nitrogen species injury to the
mammalian alveolar and airway epithelia.




Biochemistry and Molecular Genetics

Ryan, Thomas, PhD
Department of Biochemistry and
Molecular Genetics
MCLM 566, -0005

Dr. Ryan is interested in stem cell therapies in animal models of human diseases (Sickle cell disease, beta thalassemia, Cooley’s anemia).



Townes, Tim, PhD
Department of Biochemistry and
Molecular Genetics
KAUL 502, -0024

Dr. Townes works on of human hemoglobin genes as a model system
and on our understanding of basic mechanisms globin gene regulation.


Biomedical Engineering

Pollard, Andrew, PhD
Department of Biomedical Engineering
VH B140, -0019

Microscopic electrical mapping in intact heart preparations;mathematical modeling


Cell Biology

Bebok, Zsuzsanna, MD
Department of Cell Biology
MCLM 350A, -0005

Membrane protein biogenesis in epithelial cells (CFTR as model)



Genetics Research Division

Jiao, Kai, MD, PhD
Department of Genetics
KAUL 768, 0024

Reveal the functions of Tgf-beta/Bmp signaling pathway during
cardiogenesis using mice as the model system. Congenital heart
defects occur in as many as 1% of newborns, and are the leading
cause of infant morbidity and mortality.



Robin, Nathaniel, MD,
Department of Genetics
KAUL 210, 0024

My laboratory is interested in oro-facial clefting and craniofacial genetics,
and adult genetic cardiovascular disease, including Marfan syndrome.


Emergency Medicine

Wang, Henry E., MD
Emergency Medical Chair Office
OHB 233c, -7013

Currently a lead investigator for the Alabama site of the NIH-funded Resuscitation Outcome Consortium, Dr. Wang is a health services
researcher with expertise in prehospital emergency care. His primary
focus is on the safety, effectiveness and system-wide organization of
paramedic airway management techniques. Findings from his studies
have motivated changes in the organization of prehospital care systems
as well as the techniques applied in resuscitation.



Environmental Health Sciences

Bailey, Shannon, PhD
Department of Environmental Health Sciences
RPHB 623, -0022

Dr. Bailey’s lab works on molecular mechanisms of chronic alcohol
and obesity induced fatty liver disease.




Arnett, Donna, PhD
Department of Epidemiology
RPHB 210C, -0022

Dr. Arnett’s laboratory focuses on genetic and genomic determinants of
drug responses.



Ahmed, Ali, MD
Department of Medicine
Div of Gerontology, Geriatrics,
& Palliative Care
CH19 219, -2041

Quality of care, outcomes, and epidemiology of geriatric heart failure
using propensity score methods.


Anantharamaiah, GM, PhD
Department of Medicine
Div of Gerontology, Geriatrics,
& Palliative Care
BDB 668, -0012

Changes in the HDL properties when cholesterol is lowered versus
when peptides act as agonists of anti-inflammatory proteins and/or
effects of peptides on oxidized lipids in different lipid mediated
pro-inflammatory situations



Bailey, William, MD
Department of Medicine
Div of Pulmonary, Allergy,
& Critical Care
NHB 104, -7337

Clinical research in tuberculosis, asthma, and COPD with the emphasis
aimed at prevention.



Bittner, Vera, MD
Department of Medicine
Cardiovascular Diseases
LHRB 310, -0007

Secondary prevention of coronary heart disease, in particular
lipid-lowering therapy and cardiac rehabilitation.



Blalock, J. Edwin, PhD
Department of Medicine
Div of Pulmonary, Allergy,
and Critical Care
MCLM 896, -0005

Understanding the cause(s) of and potential treatments for unrelenting neutrophilic inflammation that is a driving force in many human
diseases.  Recent research has focused on airway disorders
characterized by a chronic neutrophilic inflammation such as
chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF)
and lung transplantation organ rejection.



Calhoun, David, MD
Department of Medicine
Div of Cardiovascular Disease
BMR2 430, -2180

Identifying mechanisms of resistant hypertension and in applying
this information in the development of treatment strategies to
enhance management of resistant hypertension



Chen, Yiu-Fai, PhD
Department of Medicine
Div of Cardiovascular Disease
ZRB 1008, -0007

The role of atrial natriuretic peptide (ANP) and ANP receptors in
hypoxia-induced pulmonary hypertension and remodeling and
the control of pulmonary artery pressure in normal subjects.



Dell'Italia, Lou, MD
Department of Medicine
Div of Cardiovascular Disease
BMR2 432, -2180

Dr. Dell’Italia’s research aims at understanding how the heart
changes shape and eventually falls in the process of heart failure.
He combines imaging strategies to define the heart’s function and
shape and relates these clinical markers of heart failure to
myocardial cell function and changes in the fibrous ultrastructural
that serves as a scaffolding for the myocardial cells.


Ding, Qiang (John), PhD
Department of Medicine
Div of Pulmonary, Allergy 
& Critical Care Medicine
THT 422, -0006

Dr. Ding's research is to understand the signaling proteins and
molecular mechanisms regulating cell migration and myofibroblast
differentiation, and their roles in the development of lung fibrosis. 



Gupta, Himanshu, MD
Department of Medicine
Div of Cardiovascular Disease
BDB 101, -0012

Advanced imaging modalities for the early detection and diagnosis
of cardiovascular pathology.



Lloyd, Steven, MD, PhD
Department of Medicine
Div of Cardiovascular Disease
BDB 101

Cardiovascular magnetic resonance imaging



Oparil, Suzanne, MD
Department of Medicine
Div of Cardiovascular Disease
ZRB 1034, -0007

Research in Dr. Oparil’s laboratory spans the gamut from molecular
and cellular studies to the whole animal to clinical trials.  This work
has two general themes:  1) the pathogenesis of vascular disease,
with particular emphasis on sexual dimorphism and the protective
effects of female sex hormones and 2) the pathophysiology and
treatment of high blood pressure.


Pogwizd, Steven, MD
Department of Medicine
Div. of Cardiovascular Disease
VH B140, -0019

Defining the electrophysiological and biochemical mechanisms
underlying lethal ventricular arrhythmias in the failing heart.


Prabhu, Sumanth, MD
Department of Medicine
Div of Cardiovascular Disease
THT 311, -0006

Pathophysiological mechanisms in heart failure



Rowe, Steven, MD
Department of Medicine
Div of Pulmonary, Allergy,
& Critical Care
MCLM 768, -0006

The mechanisms underlying cystic fibrosis, including agents intended
to rescue the basic CF defect; understanding the mucus clearance
defect in cystic fibrosis. 



Safford, Monika, MD
Department of Medicine
Div of Preventive Medicine
MT 643, -4410

Improving health outcomes in diabetes, quality of care, cardiovascular epidemiology.



Segrest, Jere, MD
Department of Medicine
Div of Gerontology, Geriatrics,
& Palliative Care
BDB 630, -0012

Structural biology of supramolecular assemblies (particularly
lipoproteins and membranes).



Sorscher, Eric, MD
Department of Medicine
Div of Hematology and Oncology
MCLM 798, 0005

The structure and function of CFTR and the evaluation of new
approaches to Cystic Fibrosis therapy.

Steele, Claud (Chad), PhD
Department of Medicine
Div of Pulmonary, Allergy,
& Critical Care
THT 422, -0006

Innate and adaptive immune responses to fungal pathogens of
the lung.



Thannickal, Victor, MD
Department of Medicine
Div of Pulmonary, Allergy
& Critical Care
THT 429A, -0006

Lung repair and regeneration and acute lung injury.



Young, Martin, PhD
Department of Medicine
Div of Cardiovascular Disease
ZRB 308, -0007

Role of the circadian clock within the heart.



Kabarowski, Janusz, PhD
Department of Microbiology
BBRB 334, -2170

Lipid mediated regulation of inflammation and immunity in


Klug, Chris, PhD
Department of Microbiology
SHEL 510, -2182

Dr, Klug’s lab studies the underlying mechanisms regulating
hematopoietic stem cell (HSC) developmental programs and
how they are subverted in the context of acute myeloid
leukemia (AML).



Limdi, Nita, PhD
Department of Neurology
JT 1225, -6830

The research in my laboratory explores the fundamental chemical
and biochemical mechanisms whereby the multifunctional small
radical molecule nitric oxide (NO) exerts its complex biological
effects in cancer, cellular survival and cardiovascular function.


Nutrition Sciences


Ard, Jamy, MD
Department of Nutrition Sciences
WEBB 318, -3360

Cardiovascular risk reduction and behavior modification to
reduce obesity.

Garvey, W. Timothy, MD
Department of Nutrition Sciences
WEBB 230, -3360

Combines human-based and basic technologies to study the
molecular, genetic, and metabolic pathogenesis of insulin
resistance, obesity, and Type 2 Diabetes.



Yang, Qinglin, PhD
Department of Nutrition Sciences
WEBB 435, -3360

Dr. Yang’s research focuses on cellular signaling in cardiac pathology.



Ballinger, Scott Ph.D.
Molecular and Cellular Pathology
BMR2, -2180

Dr. Ballinger’s research focus is on free radical production and
mitochondrial damage in the cardiovascular system.


Chatham, John, PhD
Molecular and Cellular Pathology
VH G001, -0019

The impact of alterations in cardiac energy metabolism and substrate utilization on cardiomyocyte function.



Chen, Yabing, PhD
Molecular and Cellular Pathology
SHEL 710, -2182

Dr. Chen works on the regulation of vascular smooth muscle cells
(VSMC) in the development of cardiovascular diseases.


Landar, Aimee, PhD
Molecular and Cellular Pathology
BMR2 506, -2182

 Redox-dependent post-translational modification of proteins and
their effects on cell signaling in the vasculature



Patel, Rakesh, PhD
Molecular & Cellular Pathology
BMR2 5327, -2180

We incorporate basic science and translational studies in pursuit of
our research interests which are to understand the molecular basis
of nitric oxide and nitrite interactions with different organs and red
blood cells and how these impact upon biological processes associated
with blood flow regulation and pulmonary function during hypoxia,
inflammation (associated with Sepsis) or in response to inhaled
irritants (e.g. chlorine gas).



Ambalavanan (Ambal), Navasivayam, M.D.
Department of Pediatrics
176 Facility Building, -9380

Our division of neonatology is one of the participating centers of the 16-center Neonatal Research Network (NRN), funded by the NICHD. Inclusion in the NRN is by competitive renewal, which remains highly competitive. The mission of the NRN is to organize multi-center clinical research studies, and the NRN has proven to be one of the primary sources of data for evidence-based practice in neonatology


Physiology & Biophysics


Bamman, Marcas, PhD
Department of Physiology
& Biophysics
MCLM 966A, -0005

Dr. Bamman’s lab focuses on sarcopenia of aging, muscle plasticity and satellite cell function, exercise physiology.


Bevensee, Mark, PhD
Department of Physiology
& Biophysics
MCLM 812, -0005

The laboratory of Dr. Bevensee is interested in the cellular and molecular physiology of intracellular pH (pHi) regulation and acid-base transport in tissues such as the brain, heart, and kidney. We are also interested in how acid-base transporters, as well as ion channels such as the epithelial Na+ channel (ENaC) contribute to Na+ hyperabsorption in mouse models of autosomal recessive polycystic kidney disease (ARPKD).


Kirk, Kevin, PhD
Department of Physiology
& Biophysics
MCLM 982B, -0005

New Paradigms of CFTR Regulation
Regulation of CFTR by Syntaxin and N-Sec 1 Isoforms
UAB CF Research and Translation Core Center’




DuBay, Derek, MD
Division of Transplantation Surgery
ZRB 701, -0007

Clinical outcomes research in liver transplantation and hepatobiliary malignancies.


George, James, PhD
Division of Cardiovascular
& Thoracic Surgery
LHRB 790, -0007

The primary focus of my work is immune regulation of post-transplant vascular disease and allograft rejection.


Woodworth, Bradford, MD
Division of Surgery
BDB 563, -0012

The pathophysiologic mechanisms in chronic rhinosinusitis; the identification of novel flavonoid compounds for the treatment of cystic fibrosis chronic rhinosinusitis