MSTP students provide a wealth of research publications focusing on neurology to cancer biology. The diversity of research found in our students' publications reinforces the concept of laboratory discoveries as they are translated to the clinical setting.

Given are current publications for review. The PMID number is provided for your convenience. 


2016

Krzywanski DM,Moellering DR,Westbrook DG,Dunham-Snary KJ,Brown J,Bray AW,Feeley KP,Sammy MJ,Smith MR,Schurr TG,Vita JA, Ambalavanan N,Calhoun D,Dell'Italia L,Ballinger SW. Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry. Circ Cardiovasc Genet.2016 Feb;9(1):26-36.doi: 10.1161/CIRCGENETICS.115.001308. Epub 2016 Jan 19. PMID: 26787433. PMCID: PMC4758889.

Cohen JL,Glover ME,Pugh PC,Fant AD,Simmons RK,Akil H,Kerman IA,Clinton SM. Maternal Style Selectively Shapes AmygdalarDevelopmentand Social Behavior in Rats Genetically Prone to High Anxiety. Dev Neurosci.2015;37(3):203-14. doi: 10.1159/000374108. Epub 2015 Mar 17. PMID: 25791846. PMCID: PMC4485591.

Burge WK,Griffis JC,Nenert R,Elkhetali A,DeCarlo DK,Ver Hoef LW,Ross LA,Visscher KM. Cortical thickness in human V1 associated with central vision loss. Sci Rep.2016 Mar 24;6:23268. doi: 10.1038/srep23268. PMID: 27009536. PMCID: PMC4806312.

Gilbert AN,Shevin RS,Anderson JC,Langford CP,Eustace N,Gillespie GY,Singh R,Willey CD. Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing. J Vis Exp.2016 Jun 9;(112). doi: 10.3791/54026. PMID: 27341166.

FoxBM,KasztanM. Endothelin receptor antagonists in sickle cell disease: A promising new therapeutic approach. Life Sci.2016 Apr 3. pii: S0024-3205(16)30220-X. doi: 10.1016/j.lfs.2016.04.001. [Epub ahead of print]. PMID: 27049871.

Hadley JA,Kraguljac NV,White DM,Ver Hoef L,Tabora J,Lahti AC.  Change in brain network topology as a function of treatment response in schizophrenia: a longitudinal resting-state fMRI study using graph theory. NPJ Schizophr.2016 Apr 27;2:16014. doi: 10.1038/npjschz.2016.14. eCollection 2016. PMID:27336056.

Kraguljac NV,White DM,Hadley N,Hadley JA,Ver Hoef L,Davis E,Lahti AC. Aberrant Hippocampal Connectivity in Unmedicated Patients With Schizophrenia and Effects of Antipsychotic Medication: A Longitudinal Resting State Functional MRI Study. Schizophr Bull.2016 Feb 12. pii: sbv228. [Epub ahead of print]. PMID: 26873890.

Engel KL,Mackiewicz M,Hardigan AA,Myers RM,Savic D. Decoding transcriptional enhancers: Evolving from annotation to functional interpretation. Semin Cell Dev Biol.2016 May 22. pii: S1084-9521(16)30140-9. doi: 10.1016/j.semcdb.2016.05.014. [Epub ahead of print]. PMID: 27224938.

Hull TD,Boddu R,Guo L,Tisher CC,Traylor AM,Patel B,Joseph R,Prabhu SD,Suliman HB,Piantadosi CA,Agarwal A,George JFHeme oxygenase-1 regulates mitochondrial quality control in the heart. JCI Insight.2016;1(2):e85817. PMID: 27110594.

Aslibekyan S,Laufer VA,Arnett DK,Bridges SL Jr. A Novel Genetic Association With Systemic Sclerosis: The Utility of Whole-Exome Sequencing in Autoimmune Disease. Arthritis Rheumatol.2016 Jan;68(1):27-30. doi: 10.1002/art.39451. PMID: 26473989.

Lever JM,Boddu R,George JF,Agarwal A. Heme Oxygenase-1 in Kidney Health and Disease. Antioxid Redox Signal.2016 May 26. [Epub ahead of print]. PMID: 26906116.

Rangarajan S,Locy ML,Luckhardt TR,Thannickal VJ. Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now? Drugs.2016 Mar;76(3):291-300.doi:10.1007/s40265-015-0523-6. PMID: 26729185.

Kurundkar AR,Kurundkar D,Rangarajan S,Locy ML,Zhou Y,Liu RM,Zmijewski J,Thannickal VJ. The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury. FASEB J.2016 Feb 16. pii: fj.201500173. [Epub ahead of print]. PMID: 26884454.

Lopker MJ,Del Prete GQ,Estes JD,Li H,Reid C,Newman L,Lipkey L,Camus C,Easlick JL,Wang S,Decker JM,Bar KJ,Learn G,Pal R, Weiss DE,Hahn BH,Lifson JD,Shaw GM,Keele BF. Derivation and characterization of pathogenic transmitted/founder molecular clones from SIVsmE660 and SIVmac251 following mucosal infection. J Virol.2016 Jul 13. pii: JVI.00718-16. [Epub ahead of print]. PMID: 27412591.

Zhang W,Wu M,Kim T,Jariwala RH,Garvey WJ,Luo N,Kang M,Ma E,Tian L,Steverson D,Yang Q,Fu Y,Garvey WT. Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High Fat Diet-Induced Insulin Resistance. Diabetes.2016 May 10. pii: db160154. [Epub ahead of print]. PMID: 27207527.

Nwaobi SE, Cuddapah VA,Patterson KC,Randolph AC,Olsen ML. Theroleof glial-specific Kir4.1 in normal and pathological states of the CNS. Acta Neuropathol.2016 Mar 9. [Epub ahead of print]. PMID: 26961251.

Kirby MK,Ramaker RC,Gertz J,Davis NS,Johnston BE,Oliver PG,Sexton KC,Greeno EW,Christein JD,Heslin MJ,Posey JA,Grizzle WE,Vickers SM,Buchsbaum DJ,Cooper SJ,Myers RMRNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4. Mol Oncol.2016 May 26. pii: S1574-7891(16)30040-0. doi: 10.1016/j.molonc.2016.05.004. [Epub ahead of print]. PMID: 27282075.

Patterson KC,Hawkins VE,Arps KM,Mulkey DK, Olsen ML. MeCP2 Deficiency Results in Robust Rett-like Behavioral and Motor Deficits in Male and Female Rats. Hum Mol Genet.2016 Jun 21. pii: ddw179. [Epub ahead of print]. PMID: 27329765.


Savic DRamaker RCRoberts BS, Dean ECBurwell TCMeadows SKCooper SJGarabedian MJGertz JMyers RM. Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation. Genome Med.2016 Jul 11;8(1):74. doi: 10.1186/s13073-016-0328-6. PMID: 27401066. PMCID: PMC4940857.


Rogers AJ,Weke E,Kwena Z,Bukusi EA,Oyaro P,Cohen CR,Turan JM. Implementation of repeat HIV testing during pregnancy in Kenya: a qualitative study. BMC Pregnancy Childbirth.2016 Jul 11;16(1):151. doi: 10.1186/s12884-016-0936-6. PMID: 27401819. PMCID: PMC4940827.


Arrant AE,Filiano AJ,Warmus BA,Hall AM,Roberson ED. Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test. Genes Brain Behav.2016 Jul;15(6):588-603. doi: 10.1111/gbb.12300. PMID: 27213486.

Weaver AN,Burch MB,Cooper TS,Della Manna DL,Wei S,Ojesina AI,Rosenthal EL,Yang ES. Notch Signaling Activation is Associated with Patient Mortality and Increased FGF1-mediated Invasion in Squamous Cell Carcinoma of the Oral Cavity. Mol Cancer Res.2016 Jun 27. pii: molcanres.0114.2016. [Epub ahead of print]. PMID: 27353029

Krzywanski DM,Moellering DR,Westbrook DG,Dunham-Snary KJ,Brown J,Bray AW,Feeley KP,Sammy MJ,Smith MR,Schurr TG,Vita JA, Ambalavanan N,Calhoun D,Dell'Italia L,Ballinger SW. Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry. Circ Cardiovasc Genet.2016 Feb;9(1):26-36.doi: 10.1161/CIRCGENETICS.115.001308. Epub 2016 Jan 19. PMID: 26787433. PMCID: PMC4758889.

Cohen JL,Glover ME,Pugh PC,Fant AD,Simmons RK,Akil H,Kerman IA,Clinton SM. Maternal Style Selectively Shapes AmygdalarDevelopmentand Social Behavior in Rats Genetically Prone to High Anxiety. Dev Neurosci.2015;37(3):203-14. doi: 10.1159/000374108. Epub 2015 Mar 17. PMID: 25791846. PMCID: PMC4485591.

Burge WK,Griffis JC,Nenert R,Elkhetali A,DeCarlo DK,Ver Hoef LW,Ross LA,Visscher KM. Cortical thickness in human V1 associated with central vision loss. Sci Rep.2016 Mar 24;6:23268. doi: 10.1038/srep23268. PMID: 27009536. PMCID: PMC4806312.

Gilbert AN,Shevin RS,Anderson JC,Langford CP,Eustace N,Gillespie GY,Singh R,Willey CD. Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing. J Vis Exp.2016 Jun 9;(112). doi: 10.3791/54026. PMID: 27341166.

FoxBM,KasztanM. Endothelin receptor antagonists in sickle cell disease: A promising new therapeutic approach. Life Sci.2016 Apr 3. pii: S0024-3205(16)30220-X. doi: 10.1016/j.lfs.2016.04.001. [Epub ahead of print]. PMID: 27049871.

Hadley JA,Kraguljac NV,White DM,Ver Hoef L,Tabora J,Lahti AC.  Change in brain network topology as a function of treatment response in schizophrenia: a longitudinal resting-state fMRI study using graph theory. NPJ Schizophr.2016 Apr 27;2:16014. doi: 10.1038/npjschz.2016.14. eCollection 2016. PMID:27336056.

Kraguljac NV,White DM,Hadley N,Hadley JA,Ver Hoef L,Davis E,Lahti AC. Aberrant Hippocampal Connectivity in Unmedicated Patients With Schizophrenia and Effects of Antipsychotic Medication: A Longitudinal Resting State Functional MRI Study. Schizophr Bull.2016 Feb 12. pii: sbv228. [Epub ahead of print]. PMID: 26873890.

Engel KL,Mackiewicz M,Hardigan AA,Myers RM,Savic D. Decoding transcriptional enhancers: Evolving from annotation to functional interpretation. Semin Cell Dev Biol.2016 May 22. pii: S1084-9521(16)30140-9. doi: 10.1016/j.semcdb.2016.05.014. [Epub ahead of print]. PMID: 27224938.

Hull TD,Boddu R,Guo L,Tisher CC,Traylor AM,Patel B,Joseph R,Prabhu SD,Suliman HB,Piantadosi CA,Agarwal A,George JFHeme oxygenase-1 regulates mitochondrial quality control in the heart. JCI Insight.2016;1(2):e85817. PMID: 27110594.

Aslibekyan S,Laufer VA,Arnett DK,Bridges SL Jr. A Novel Genetic Association With Systemic Sclerosis: The Utility of Whole-Exome Sequencing in Autoimmune Disease. Arthritis Rheumatol.2016 Jan;68(1):27-30. doi: 10.1002/art.39451. PMID: 26473989.

Lever JM,Boddu R,George JF,Agarwal A. Heme Oxygenase-1 in Kidney Health and Disease. Antioxid Redox Signal.2016 May 26. [Epub ahead of print]. PMID: 26906116.

Rangarajan S,Locy ML,Luckhardt TR,Thannickal VJ. Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now? Drugs.2016 Mar;76(3):291-300.doi:10.1007/s40265-015-0523-6. PMID: 26729185.

Kurundkar AR,Kurundkar D,Rangarajan S,Locy ML,Zhou Y,Liu RM,Zmijewski J,Thannickal VJ. The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury. FASEB J.2016 Feb 16. pii: fj.201500173. [Epub ahead of print]. PMID: 26884454.

Lopker MJ,Del Prete GQ,Estes JD,Li H,Reid C,Newman L,Lipkey L,Camus C,Easlick JL,Wang S,Decker JM,Bar KJ,Learn G,Pal R, Weiss DE,Hahn BH,Lifson JD,Shaw GM,Keele BF. Derivation and characterization of pathogenic transmitted/founder molecular clones from SIVsmE660 and SIVmac251 following mucosal infection. J Virol.2016 Jul 13. pii: JVI.00718-16. [Epub ahead of print]. PMID: 27412591.

Zhang W,Wu M,Kim T,Jariwala RH,Garvey WJ,Luo N,Kang M,Ma E,Tian L,Steverson D,Yang Q,Fu Y,Garvey WT. Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High Fat Diet-Induced Insulin Resistance. Diabetes.2016 May 10. pii: db160154. [Epub ahead of print]. PMID: 27207527.

Nwaobi SE, Cuddapah VA,Patterson KC,Randolph AC,Olsen ML. Theroleof glial-specific Kir4.1 in normal and pathological states of the CNS. Acta Neuropathol.2016 Mar 9. [Epub ahead of print]. PMID: 26961251.

Kirby MK,Ramaker RC,Gertz J,Davis NS,Johnston BE,Oliver PG,Sexton KC,Greeno EW,Christein JD,Heslin MJ,Posey JA,Grizzle WE,Vickers SM,Buchsbaum DJ,Cooper SJ,Myers RMRNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4. Mol Oncol.2016 May 26. pii: S1574-7891(16)30040-0. doi: 10.1016/j.molonc.2016.05.004. [Epub ahead of print]. PMID: 27282075.

Patterson KC,Hawkins VE,Arps KM,Mulkey DK, Olsen ML. MeCP2 Deficiency Results in Robust Rett-like Behavioral and Motor Deficits in Male and Female Rats. Hum Mol Genet.2016 Jun 21. pii: ddw179. [Epub ahead of print]. PMID: 27329765.

Savic DRamaker RCRoberts BS, Dean ECBurwell TCMeadows SKCooper SJGarabedian MJGertz JMyers RM. Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation. Genome Med.2016 Jul 11;8(1):74. doi: 10.1186/s13073-016-0328-6. PMID: 27401066. PMCID: PMC4940857.

Rogers AJ,Weke E,Kwena Z,Bukusi EA,Oyaro P,Cohen CR,Turan JM. Implementation of repeat HIV testing during pregnancy in Kenya: a qualitative study. BMC Pregnancy Childbirth.2016 Jul 11;16(1):151. doi: 10.1186/s12884-016-0936-6. PMID: 27401819. PMCID: PMC4940827.

Arrant AE,Filiano AJ,Warmus BA,Hall AM,Roberson ED. Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test. Genes Brain Behav.2016 Jul;15(6):588-603. doi: 10.1111/gbb.12300. PMID: 27213486.

Weaver AN,Burch MB,Cooper TS,Della Manna DL,Wei S,Ojesina AI,Rosenthal EL,Yang ES. Notch Signaling Activation is Associated with Patient Mortality and Increased FGF1-mediated Invasion in Squamous Cell Carcinoma of the Oral Cavity. Mol Cancer Res.2016 Jun 27. pii: molcanres.0114.2016. [Epub ahead of print]. PMID: 27353029