MSTP students provide a wealth of research publications focusing on neurology to cancer biology. The diversity of research found in our students' publications reinforces the concept of laboratory discoveries as they are translated to the clinical setting.

Given are current publications for review. The PMID number is provided for your convenience. 


2017

Albertson AJBohannon ASHablitz JJ. HCN Channel Modulation of Synaptic Integration in GABAergic Interneurons in Malformed Rat Neocortex. Front Cell Neurosci. 2017 Apr 19;11:109. doi: 10.3389/fncel.2017.00109. eCollection 2017. PMID: 28469560.  PMCID: PMC5396479.

Iraci NGaude ELeonardi TCosta ASHCossetti CPeruzzotti-Jametti LBernstock JDSaini HKGelati MVescovi ALBastos CFaria NOcchipinti LGEnright AJFrezza CPluchino S. Extracellular vesicles are independent metabolic units with asparaginase activity. Nat Chem Biol. 2017 Jul 3. doi: 10.1038/nchembio.2422. [Epub ahead of print]. PMID:28671681.

Bray AWBallinger SW. Mitochondrial DNA mutations and cardiovascular disease. Curr Opin Cardiol. 2017 Feb 4. doi: 10.1097/HCO.0000000000000383. [Epub ahead of print]. PMID: 28169948.

Cohen JLJackson NLBallestas MEWebb WMLubin FDClinton SM. Amygdalar expression of the microRNA miR-101a and its target Ezh2 contribute to rodent anxiety-like behavior. Eur J Neurosci. 2017 Jun 14. doi: 10.1111/ejn.13624. [Epub ahead of print]. PMID: 28612962.

Dussaq AStackhouse CAnderson JAlmeida JWilley C. Creation of an Analytical Platform for Integrative Molecular Profiling of Glioblastoma Xenolines. Am J Clin Pathol. 2017 Mar 1;147(suppl_2):S171-S172. doi: 10.1093/ajcp/aqw191.042. PMID: 28339874. 

Duke CGKennedy AJGavin CFDay JJSweatt JD. Experience-dependent epigenomic reorganization in the hippocampus. Learn Mem. 2017 Jun 15;24(7):278-288. doi: 10.1101/lm.045112.117. Print 2017 Jul. PMID: 28620075.

Rohrbach TDJones RBHicks PHWeaver ANCooper TSEustace NJYang ESJarboe JSAnderson JCWilley CD. MARCKS phosphorylation is modulated by a peptide mimetic of MARCKS effector domain leading to increased radiation sensitivity in lung cancer cell lines. Oncol Lett. 2017 Mar;13(3):1216-1222. doi: 10.3892/ol.2016.5550. Epub 2016 Dec 29. PMID: 28454237. PMCID: PMC5403188.

Figge DStandaert DG. Dysregulation of BET proteins in levodopa-induced dyskinesia. Neurobiol Dis. 2017 Mar 9. pii: S0969-9961(17)30050-5. doi: 10.1016/j.nbd.2017.03.003. [Epub ahead of print]  PMID: 28286180.

Kasztan MFox BMSpeed JSDe Miguel CGohar EYTownes TMKutlar APollock JSPollock DM. Long-Term Endothelin-A Receptor Antagonism Provides Robust Renal Protection in Humanized Sickle Cell Disease Mice. J Am Soc Nephrol. 2017 Mar 27. pii: ASN.2016070711. doi: 10.1681/ASN.2016070711. [Epub ahead of print]. PMID: 28348063.

Kraguljac NVWhite DMHadley NHadley JAVer Hoef LDavis ELahti AC. Aberrant Hippocampal Connectivity in Unmedicated Patients With Schizophrenia and Effects of Antipsychotic Medication: A Longitudinal Resting State Functional MRI Study. Schizophr Bull. 2016 Jul;42(4):1046-55. doi: 10.1093/schbul/sbv228. Epub 2016 Feb 12. PMID:26873890. PMCID:PMC4903060 [Available on 2017-07-01].

Harms FLGirisha KMHardigan AAKortüm FShukla AAlawi MDalal ABrady LTarnopolsky MBird LMCeulemans SBebin MBowling KMHiatt SMLose EJPrimiano MChung WKJuusola JAkdemir ZCBainbridge MCharng WLDrummond-Borg MEldomery MKEl-Hattab AWSaleh MABézieau SCogné BIsidor BKüry SLupski JRMyers RMCooper GMKutsche K. Mutations in EBF3 Disturb Transcriptional Profiles and Cause Intellectual Disability, Ataxia, and Facial Dysmorphism. Am J Hum Genet. 2017 Jan 5;100(1):117-127. doi: 10.1016/j.ajhg.2016.11.012.  PMID: 28017373. PMCID: PMC5223027.

Kennell T JrDempsey DMCimino JJ. i3b3: Infobuttons for i2b2 as a Mechanism for Investigating the Information Needs of Clinical Researchers. AMIA Annu Symp Proc. 2017 Feb 10;2016:696-704. eCollection 2016. PMID: 28269866.  PMCID: PMC5333310.

Martens GRReyes LMButler JRLadowski JMEstrada JLSidner RAEckhoff DETector MTector AJ. Humoral Reactivity of Renal Transplant-Waitlisted Patients to Cells from GGTA1/CMAH/B4GalNT2, and SLA Class I Knockout Pigs. Transplantation. 2017 Apr;101(4):e86-e92. doi: 10.1097/TP.0000000000001646. PMID: 28114170.

Butler JRSantos RMN, Martens GR, Ladowski JMWang ZYLi PTector MTector AJ. Efficient generation of targeted and controlled mutational events in porcine cells using nuclease-directed homologous recombination. J Surg Res. 2017 May 15;212:238-245. doi: 10.1016/j.jss.2017.01.025. Epub 2017 Jan 29. PMID: 28550913.

Danila MILaufer VAReynolds RJYan QLiu NGregersen PKLee AKern MLangefeld CDArnett DKBridges SL Jr. Dense Genotyping of Immune-Related Regions Identifies Loci for Rheumatoid Arthritis Risk and Damage in African Americans. Mol Med. 2017 Jun 29;23. doi: 10.2119/molmed.2017.00081. [Epub ahead of print]. PMID: 28681901.

Laufer VAChen JYLangefeld CDBridges SL Jr. Integrative Approaches to Understanding the Pathogenic Role of Genetic Variation in Rheumatic Diseases. Rheum Dis Clin North Am. 2017 Aug;43(3):449-466. doi: 10.1016/j.rdc.2017.04.012. PMID: 28711145.

Kim HGLeGrand JSwindle CSNick HJOster RAChen DPurohit-Ghelani SCotta CVKo RGartland LReddy VHiebert SWFriedman ADKlug CA. The assembly competence domain is essential for inv(16)-associated acute myeloid leukemia. Leukemia. 2017 Jul 28. doi: 10.1038/leu.2017.236. [Epub ahead of print]. PMID: 28751774.

George JLever JMAgarwal A. Mononuclear phagocyte subpopulations in the mouse kidney. Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F640-F646. doi: 10.1152/ajprenal.00369.2016. Epub 2017 Jan 18. PMID: 28100500.

Adedoyin OBoddu RTraylor AMLever JMBolisetty SGeorge JAgarwal A. Heme Oxygenase-1 Mitigates Ferroptosis in Renal Proximal Tubule Cells. Am J Physiol Renal Physiol. 2017 May 17:ajprenal.00044.2017. doi: 10.1152/ajprenal.00044.2017. [Epub ahead of print]. PMID: 28515173.

Lopker MJDel Prete GQEstes JDLi HReid CNewman LLipkey LCamus CEaslick JLWang SDecker JMBar KJLearn GPal RWeiss DEHahn BHLifson JDShaw GMKeele BF. Derivation and Characterization of Pathogenic Transmitted/Founder Molecular Clones from Simian Immunodeficiency Virus SIVsmE660 and SIVmac251 following Mucosal Infection. J Virol. 2016 Sep 12;90(19):8435-53. doi: 10.1128/JVI.00718-16. Print 2016 Oct 1. PMID: 27412591. PMCID: PMC5021393.

Zhang WWu MKim TJariwala RHGarvey WJLuo NKang MMa ETian LSteverson DYang QFu YGarvey WT. Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet-Induced Insulin Resistance. Diabetes. 2016 Aug;65(8):2380-91. doi: 10.2337/db16-0154. Epub 2016 May 10. PMID:27207527. PMCID:PMC4955990 [Available on 2017-08-01].

Evonuk KSMoseley CEDoyle REWeaver CTDeSilva TM. Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination. J Vis Exp. 2016 Sep 12;(115). doi: 10.3791/54348. PMID: 27685467. PMCID: PMC5092010.

Fernandez TFKraus ACOlson KM. A Call for Residents to Get More Involved With Student-Run Free Clinics. Acad Med. 2017 May;92(5):577. PMID: 28441200. Student and Resident Letters to the Editor: Empathy and Learning Environment.

Jordan SJOlson KMBarnes SWilson LSBerryhill TFBakshi RBrown LTPress CGGeisler WM. Lower Levels of Cervicovaginal Tryptophan are Associated with Natural Clearance of Chlamydia in Women. J Infect Dis. 2017 May 17. doi: 10.1093/infdis/jix240. [Epub ahead of print]. PMID: 28520912.

Patterson KCHawkins VEArps KMMulkey DKOlsen ML. MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats. Hum Mol Genet. 2016 Aug 1;25(15):3303-3320. doi: 10.1093/hmg/ddw179. Epub 2016 Jun 21. PMID: 28201743.

Brahma MKPepin MEWende AR. My Sweetheart Is Broken: Role of Glucose in Diabetic Cardiomyopathy. Diabetes Metab J. 2017 Feb;41(1):1-9. doi: 10.4093/dmj.2017.41.1.1. PMID: 28236380.

Ramaker RCLasseigne BNHardigan AAPalacio LGunther DSMyers RMCooper SJ. RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature. Oncotarget. 2017 Apr 8. doi: 10.18632/oncotarget.16961. [Epub ahead of print]. PMID: 28454104.

Ramaker RCBowling KMLasseigne BNHagenauer MHHardigan AADavis NSGertz JCartagena PMWalsh DMVawter MPJones EGSchatzberg AFBarchas JDWatson SJBunney BGAkil HBunney WELi JZCooper SJMyers RM. Post-mortem molecular profiling of three psychiatric disorders. Genome Med. 2017 Jul 28;9(1):72. doi: 10.1186/s13073-017-0458-5. PMID: 28754123.

Turner TBMeza-Perez SLondoño AKatre APeabody JESmith HJForero ANorian LAStraughn JM JrBuchsbaum DJRandall TDArend RC. Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth. Oncotarget. 2017 Apr 24. doi: 10.18632/oncotarget.17395. [Epub ahead of print]. PMID: 28498806.

Alonso ALasseigne BNWilliams KNielsen JRamaker RCHardigan AAJohnston BRoberts BSCooper SJMarsal SMyers RM. aRNApipe: A balanced, efficient and distributed pipeline for processing RNA-seq data in highperformance computing environments. Bioinformatics. 2017 Jan 19. pii: btx023. doi: 10.1093/bioinformatics/btx023. [Epub ahead of print]. PMID: 28108448.

Savic DRamaker RCRoberts BSDean ECBurwell TCMeadows SKCooper SJGarabedian MJGertz JMyers RM. Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation. Genome Med. 2016 Jul 11;8(1):74. doi: 10.1186/s13073-016-0328-6. PMID: 27401066. PMCID: PMC4940857.

Kirby MKRamaker RCRoberts BSLasseigne BNGunther DSBurwell TCDavis NSGulzar ZGAbsher DMCooper SJBrooks JDMyers RM. Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns. BMC Cancer. 2017 Apr 17;17(1):273. doi: 10.1186/s12885-017-3252-2. PMID: 28412973. PMCID: PMC5392915.

Dulaney CMarcrom SStanley JYang ES. Poly(ADP-ribose) polymerase activity and inhibition in cancer. Semin Cell Dev Biol. 2017 Jan 10. pii: S1084-9521(17)30009-5. doi: 10.1016/j.semcdb.2017.01.007. [Epub ahead of print]. PMID: 28087320.

Abdelmotilib HMaltbie TDelic VLiu ZHu XFraser KBMoehle MSStoyka LAnabtawi NKrendelchtchikova VVolpicelli-Daley LAWest A. α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration. Neurobiol Dis. 2017 May 30;105:84-98. doi: 10.1016/j.nbd.2017.05.014. [Epub ahead of print]. PMID:28576704.

Volpicelli-Daley LAKirik D, Stoyka LE, Standaert DGHarms AS. How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease? J Neurochem. 2016 Oct;139 Suppl 1:131-155. doi: 10.1111/jnc.13627. Epub 2016 May 4. PMID: 27018978. PMCID: PMC5040622. (Review)

Volpicelli-Daley LAAbdelmotilib HLiu ZStoyka LDaher JPMilnerwood AJUnni VKHirst WDYue ZZhao HTFraser KKennedy REWest AB. G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons. J Neurosci. 2016 Jul 13;36(28):7415-27. doi: 10.1523/JNEUROSCI.3642-15.2016. PMID: 27413152. PMCID: PMC4945663.

Arrant AEFiliano AJWarmus BAHall AMRoberson ED. Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test. Genes Brain Behav. 2016 Jul;15(6):588-603. doi: 10.1111/gbb.12300. PMID: 27213486.

Zeng LBeggs RRCooper TSWeaver ANYang ES. Combining Chk1/2 inhibition with cetuximab and radiation enhances in vitro and in vivo cytotoxicity in head and neck squamous cell carcinoma. Mol Cancer Ther. 2017 Jan 30. pii: molcanther.0352.2016. doi: 10.1158/1535-7163.MCT-16-0352. [Epub ahead of print]. PMID: 28138028.

Weaver ANMcCaw TRFifolt MHites LLorenz RG. Impact of elective versus required medical school research experiences on career outcomes. J Investig Med. 2017 Mar 7. pii: jim-2016-000352. doi: 10.1136/jim-2016-000352. [Epub ahead of print]. PMID: 28270407.

Webb WMSanchez RGPerez GButler AAHauser RMRich MCO'Bierne ALJarome TJLubin FD. Dynamic association of epigenetic H3K4me3 and DNA 5hmC marks in the dorsal hippocampus and anterior cingulate cortex following reactivation of a fear memory. Neurobiol Learn Mem. 2017 Feb 20. pii: S1074-7427(17)30022-9. doi: 10.1016/j.nlm.2017.02.010. [Epub ahead of print]. PMID: 28232238.

Webb WM.  USMLE Step 1 Score Creep Adversely Affects Dual-Degree Students. Academic Medicine: June 2017 - Volume 92 - Issue 6 - p 732–733. Student and Resident Letters to the Editor: Admissions, Assessment, and Advocacy.