MSTP students provide a wealth of research publications focusing on neurology to cancer biology. The diversity of research found in our students' publications reinforces the concept of laboratory discoveries as they are translated to the clinical setting.

Given are current publications for review. The PMID number is provided for your convenience.



Nakahara H, Herrin BR, Alder MN, Catera R, Yan XJ, Chiorazzi N, Cooper MD.  Chronic lymphocytic leukemia monitoring with a Lamprey idiotope-specific antibody.  Cancer Immunol Res. 2013 Oct;1(4):223-8. doi: 10.1158/2326-6066.CIR-13-0052.  PMID: 24432304.  PMCID: PMC3888878.

Feeley KP, Bray AW, Westbrook DG, Johnson LW, Kesterson RA, Ballinger SW, Welch DR. Mitochondrial Genetics Regulate Breast Cancer Tumorigenicity and Metastatic Potential. Cancer Res. 2015 Oct 15;75(20):4429-36. doi: 10.1158/0008-5472.CAN-15-0074. PMID: 26471915. PMCID: PMC4610037.

Brossier NM, Prechtl AM, Longo JF, Barnes S, Wilson LS, Byer SJ, Brosius SN, Carroll SL. Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells. J Neuropathol Exp Neurol. 2015 Jun;74(6):568-586. PMID: 25946318. PMCID: PMC4433624

Cohen JL, Glover ME, Pugh PC, Fant AD, Simmons RK, Akil H, Kerman IA, Clinton SM. Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety. Dev Neurosci. 2015;37(3):203-14. PMID: 25791846.

Glover ME, Pugh PC, Jackson NL, Cohen JL, Fant AD, Akil H, Clinton SM. Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats. Neuroscience. 2015 Jan 22;284:775-97. doi: 10.1016/j.neuroscience.2014.10.044. Epub 2014 Nov 4. PMID: 25451292. PMCID: PMC4267992.

Dobbin ZC, Katre AA, Steg AD, Erickson BK, Shah MM, Alvarez RD, Conner MG, Schneider D, Chen D, Landen CN. Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer. Oncotarget. 2014 Sep 30;5(18):8750-64. PMID: 25209969. PMCID: PMC4226719.

Steg AD, Burke MR, Amm HM, Katre AA, Dobbin ZC, Jeong DH, Landen CN. Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer. Oncotarget. 2014 Aug 30;5(16):7065-80. PMID: 25216523. PMCID: PMC4196184.

Griffis JC, Elkhetali AS, Vaden RJ, Visscher KM. Distinct effects of trial-driven and task Set-related control in primary visual cortex. Neuroimage. 2015 Jul 9. pii: S1053-8119(15)00614-X. doi: 10.1016/j.neuroimage.2015.07.005. [Epub ahead of print]. PMID: 26163806

Griffis JC, Elkhetali AS, Burge WK, Chen RH, Visscher KM. Retinotopic patterns of background connectivity between V1 and fronto-parietal cortex are modulated by task demands. Front Hum Neurosci. 2015 Jun 8;9:338. doi: 10.3389/fnhum.2015.00338. eCollection 2015. PMID: 26106320. PMCID: PMC4458688.

Elkhetali AS, Vaden RJ, Pool SM, Visscher KM. Early visual cortex reflects initiation and maintenance of task set. Neuroimage. 2015 Feb 15;107:277-88. doi: 10.1016/j.neuroimage.2014.11.061. Epub 2014 Dec 6. PMID:25485712. PMCID: PMC4303470

Speed JS, Heimlich JB, Hyndman KA, Fox BM, Patel V, Yanagisawa M, Pollock JS, Titze JM, Pollock DM.  Endothelin-1 as a master regulator of whole-body Na+ homeostasis. FASEB J. 2015 Aug 12. pii: fj.15-276584. [Epub ahead of print]. PMID: 26268928.

Hutcheson NL, Sreenivasan KR, Deshpande G, Reid MA, Hadley J, White DM, Ver Hoef L, Lahti AC. Effective connectivity during episodic memory retrieval in schizophrenia participants before and after antipsychotic medication. Hum Brain Mapp. 2015 Apr;36(4):1442-57. doi: 10.1002/hbm.22714. Epub 2014 Dec 11. PMID: 25504918.

McCullumsmith RE, Hammond JH, Shan D, Meador-Woodruff JH. Postmortem brain: an underutilized substrate for studying severe mental illness. Neuropsychopharmacology. 2015 Mar 13;40:1307. doi: 10.1038/npp.2014.337. PMID: 25767083.

McGuire JL, Hammond JH, Yates SD, Chen D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.  Altered serine/threonine kinase activity in schizophrenia.  Brain Res. 2014 Jun 3;1568:42-54. doi: 10.1016/j.brainres.2014.04.029. Epub 2014 Apr 26.  PMID: 24780530.  PMCID: PMC4096904.

Roberts BS, Hardigan AA, Kirby MK, Fitz-Gerald MB, Wilcox CM, Kimberly RP, Myers RM.  Blocking of targeted microRNAs from next-generation sequencing libraries.  Nucleic Acids Res. 2015 Jul 23. pii: gkv724. [Epub ahead of print].  PMID: 26209131.

Hull TD, Kamal AI, Boddu R, Bolisetty S, Guo L, Tisher CC, Rangarajan S, Chen B, Curtis LM, George JF, Agarwal A. Heme Oxygenase-1 Regulates Myeloid Cell Trafficking in AKI. J Am Soc Nephrol. 2015 Sep;26(9):2139-51. doi: 10.1681/ASN.2014080770. Epub 2015 Feb 12. PMID: 25677389. PMCID: PMC4552119.

Bolisetty S, Zarjou A, Hull TD, Traylor AM, Perianayagam A, Joseph R, Kamal AI, Arosio P, Soares MP, Jeney V, Balla J, George JF, Agarwal A. Macrophage and epithelial cell H-ferritin expression regulates renal inflammation. Kidney Int. 2015 Apr 15. doi: 10.1038/ki.2015.102. [Epub ahead of print]. PMID: 25874599.

Boddu R, Hull TD, Bolisetty S, Hu X, Moehle MS, Daher JP, Kamal AI, Joseph R, George JF, Agarwal A, Curtis LM4West AB. Leucine-Rich Repeat Kinase 2 Deficiency is Protective in Rhabdomyolysis-Induced Kidney Injury. Hum Mol Genet. 2015 Apr 22. pii: ddv147. [Epub ahead of print]. PMID: 25904107.

Rohrbach TD, Shah N, Jackson WP, Feeney EV, Scanlon S, Gish R, Khodadadi R, Hyde SO, Hicks PH, Anderson JC, Jarboe JS, Willey CD. The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization. PLoS One. 2015 Oct 15;10(10):e0140870. doi: 10.1371/journal.pone.0140870. eCollection 2015. PMID: 26470026.

Aslibekyan S, Laufer VA, Arnett DK, Bridges SL. A novel genetic association with systemic sclerosis: The utility of whole exome sequencing in autoimmune disease. Arthritis Rheumatol. 2015 Oct 16. doi: 10.1002/art.39451. [Epub ahead of print]. PMID: 26473989.

Pennathur S, Vivekanandan-Giri A, Locy ML, Kulkarni T, Zhi D, Zeng L, Byun J, de Andrade JA, Thannickal VJ. Oxidative Modifications of Protein Tyrosyl Residues are Increased in Plasma of Human Subjects with Interstitial Lung Disease. Am J Respir Crit Care Med. 2015 Nov 17. [Epub ahead of print]. PMID:26575972.

Ravi S, Johnson MS, Chacko BK, Kramer PA, Sawada H, Locy ML, Wilson LS, Barnes S, Marques MB, Darley-Usmar VM. Modification of platelet proteins by 4-hydroxynonenal: Potential Mechanisms for inhibition of aggregation and metabolism. Free Radic Biol Med. 2015 Oct 14. pii: S0891-5849(15)01077-1. doi: 10.1016/j.freeradbiomed.2015.10.408. [Epub ahead of print]. PMID: 26475426.

Steverson D Jr, Tian L, Fu Y, Zhang W, Ma E, Garvey WT.  Tribbles Homolog 3 Promotes Foam Cell Formation Associated with Decreased Proinflammatory Cytokine Production in Macrophages: Evidence for Reciprocal Regulation of Cholesterol Uptake and Inflammation. Metab Syndr Relat Disord. 2015 Nov 19. [Epub ahead of print] PMID: 26584255.

Stec MJ, Mayhew DL, Bamman MM. The effects of age and resistance loading on skeletal muscle ribosome biogenesis. J Appl Physiol (1985). 2015 Aug 20:jap.00489.2015. doi: 10.1152/japplphysiol.00489.2015. [Epub ahead of print]. PMID: 26294750.

Meadows JP, Guzman-Karlsson MC, Phillips S, Holleman C, Posey JL, Day JJ, Hablitz JJ, Sweatt JD. DNA methylation regulates neuronal glutamatergic synaptic scaling. Sci Signal. 2015 Jun 23;8(382):ra61. doi: 10.1126/scisignal.aab0715. PMID: 26106219.

Evonuk KS, Baker BJ, Doyle RE, Moseley CE, Sestero CM, Johnston BP, De Sarno P, Tang A, Gembitsky I, Hewett SJ, Weaver CT, Raman C, DeSilva TM. Inhibition of System Xc- Transporter Attenuates Autoimmune Inflammatory Demyelination. J Immunol. 2015 Jul 15;195(2):450-63. doi: 10.4049/jimmunol.1401108. Epub 2015 Jun 12.. [Epub ahead of print]. PMID: 26071560. PMCID: PMC4490999.

Nwaobi SE, Olsen ML. Correlating Gene-specific DNA Methylation Changes with Expression and Transcriptional Activity of Astrocytic KCNJ10 (Kir4.1). J Vis Exp. 2015 Sep 26;(103). doi: 10.3791/52406. PMID:26436772.

Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP Jr, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN,Mouquet H, Martin L, Acharya P, Zhang B, Kwong PD, Mascola JR, Verrips CT, Strokappe NM, Rutten L, McCoy LE, Weiss RA, Brown CS,Jackson R, Silvestri G, Connors M, Burton DR, Shaw GM, Nussenzweig MC, Bjorkman PJ, Ho DD, Farzan M, Hahn BH. Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas. MBio. 2015 Apr 21;6(2). pii: e00296-15. doi: 10.1128/mBio.00296-15. PMID: 25900654. PMCID:PMC4453581.

Ehrhardt A, Chung WJ, Pyle LC, Wang W, Nowotarski K, Mulvihill CM, Ramjeesingh M, Hong J, Velu SE, Lewis HA, Atwell S, Aller S, Bear CE,Lukacs GL, Kirk KL, Sorscher EJ. Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop. J Biol Chem. 2015 Dec 1. pii: jbc.M115.704809. [Epub ahead of print]. PMID: 26627831.

Robert SM, Buckingham SC, Campbell SL, Robel S, Holt KT, Ogunrinu-Babarinde T, Warren PP, White DM, Reid MA, Eschbacher JM, Berens ME, Lahti AC, Nabors LB, Sontheimer H. SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma. Sci Transl Med. 2015 May 27;7(289):289ra86. doi: 10.1126/scitranslmed.aaa8103. PMID: 26019222.

Campbell SL, Robel S, Cuddapah VA, Robert S, Buckingham SC, Kahle KT, Sontheimer H. GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy. Glia. 2015 Jan;63(1):23-36. doi: 10.1002/glia.22730. Epub 2014 Jul 26. PMID: 25066727.  PMCID: PMC4237714.

Calfa G, Li W, Rutherford JM, Pozzo-Miller L. Excitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 of Mecp2 knockout mice. Hippocampus. 2015 Feb;25(2):159-68. doi: 10.1002/hipo.22360. Epub 2014 Sep 25.  PMID: 25209930.  PMCID: PMC4300269.

Singer JR, Weaver CT.  Daughter's Tolerance of Mom Matters in Mate Choice.  Cell. 2015 Jul 30;162(3):467-9. doi: 10.1016/j.cell.2015.07.030.  PMID: 26232215. PMCID: PMC4669059.

Stanley J, Klepczyk L, Keene K, Wei S, Li Y, Forero A, Grizzle W, Wielgos M, Brazelton J, LoBuglio AF, Yang ES. PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers. Breast Cancer Res Treat. 2015 Apr;150(3):569-79. doi: 10.1007/s10549-015-3359-6. Epub 2015 Apr 2. PMID: 25833211.

Stoddard MB, Li H, Wang S, Saeed M, Andrus L, Ding W, Jiang X, Learn GH, von Schaewen M, Wen J, Goepfert PA, Hahn BH, Ploss A, Rice CM, Shaw GM. Identification, Molecular Cloning, and Analysis of Full-Length Hepatitis C Virus Transmitted/Founder Genotypes 1, 3, and 4. MBio. 2015 Feb 24;6(2). pii: e02518-14. doi: 10.1128/mBio.02518-14. PMID: 25714714.

Mitchell AM, Stone AE, Cheng L, Ballinger K, Edwards MG, Stoddard M, Li H, Golden-Mason L, Shaw GM, Khetani S,Rosen HR. Transmitted/Founder Hepatitis C Viruses Induce Cell-Type- and Genotype-Specific Differences in Innate Signaling within the Liver. MBio. 2015 Feb 24;6(2). pii: e02510-14. doi: 10.1128/mBio.02510-14. PMID: 25714713.

Kell A, Stoddard M, Li H, Marcotrigiano J, Shaw GM, Gale M Jr.  PAMP Recognition of Hepatitis C Virus Transmitted/founder Variants by RIG-I is dependent on U-Core length.  J Virol. 2015 Aug 26. pii: JVI.01964-15. [Epub ahead of print].  PMID: 26311867.

Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM7, Gale M Jr, Shah VH0, Rosen HR. Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication. Gastroenterology. 2015 Feb;148(2):392-402.e13. doi: 10.1053/j.gastro.2014.10.040. Epub 2014 Nov 4. PMID: 25447848.

Li H, Stoddard M, Wang S, Giorgi EE, Blair L, Learn G, Hahn B, Alter H, Busch M, Fierer D, Ribeiro RM, Perelson AS, Bhattacharya T, Shaw GM. Single Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification. J Virol. 2015 Oct 14. pii: JVI.02156-15. [Epub ahead of print]. PMID: 26468546.

Thomas EM, Popple RA, Markert JM, Fiveash JB. In Reply: Volumetric Arc Therapy (RapidArc) Vs Gamma Knife Radiosurgery for Multiple Brain Metastases: Not Only a Dosimetric Issue. Neurosurgery. Neurosurgery. 2015 Mar;76(3):E353-4. doi: 10.1227/NEU.0000000000000662.. PMID: 25951033.

Tannazi F, Huang M, Thomas E, Duan J, Wu X, Shen S, Cardan R, Fiveash J, Brezovich I, Popple R. SU-E-T-291: Dosimetric Accuracy of Multitarget Single Isocenter Radiosurgery. Med Phys. 2015 Jun;42(6):3400. doi: 10.1118/1.4924653. PMID: 26127957.

Weaver AN, Cooper TS, Rodriguez M, Trummell HQ, Bonner JA, Rosenthal EL, Yang ES.  DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma.  Oncotarget. 2015 Aug 22. [Epub ahead of print].  PMID: 26336991.

Rohrbach TD, Jarboe JS, Anderson JC, Trummell HQ, Hicks PH, Weaver AN, Yang ES, Oster RA, Deshane JS, Steele C, Siegal GP, Bonner JA, Willey CD.  Targeting the effector domain of the myristoylated alanine rich C-kinase substrate enhances lung cancer radiation sensitivity. Int J Oncol. 2015 Mar;46(3):1079-88. doi: 10.3892/ijo.2014.2799. Epub 2014 Dec 17. Int J Oncol. 2015 Mar;46(3):1079-88. doi: 10.3892/ijo.2014.2799. Epub 2014 Dec 17. PMID: 25524703.

Butler AA, Webb WM, Lubin FD. Regulatory RNAs and control of epigenetic mechanisms: expectations for cognition and cognitive dysfunction. Epigenomics. 2015 Sep 14. [Epub ahead of print]. PMID: 26366811.

Basu R, Whitley SK, Bhaumik S, Zindl CL, Schoeb TR, Benveniste EN, Pear WS, Hatton RD, Weaver CT. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat Immunol. 2015 Mar;16(3):286-95. doi: 10.1038/ni.3099. Epub 2015 Feb 2. PMID: 25642823.

Witte S, O'Shea JJ, Vahedi G. Super-enhancers: Asset management in immune cell genomes. Trends Immunol. 2015 Sep;36(9):519-26. doi: 10.1016/ Epub 2015 Aug 12.  PMID:26277449.

Witte S, Bradley A, Enright AJ, Muljo SA. High-density P300 enhancers control cell state transitions. BMC Genomics. 2015 Nov 6;16:903. doi: 10.1186/s12864-015-1905-6. PMID: 26546038. PMCID: PMC4636788.