UAB is home to many advances in nephrology, including its status as an international leader in kidney transplantation. UAB physicians pioneered novel kidney donor matching with non-exact matches, which opened doors to the thousands of patients in need of kidneys.
Early research at UAB confirmed the important role kidneys play in maintaining healthy blood pressure, and later research by the Division centered on high blood pressure related to salt sensitivity in African-Americans.
Research on Autosomal Recessive Polycycstic Kidney Disease is ongoing at UAB, and at least one gene has been identified so far.
UAB is home to the first infusion of enzyme replacement therapy in the U.S. The therapy treated Fabry disease, a life-threatening disorder for which there had been no effective treatment. Five years later, the first “orphan drug” (a drug for a rare disease) for Fabry disease was administered.