Epilepsy Research


Research areas of interest include neuroimaging, epilepsy surgery, and pharmacology with new anticonvulsant drugs. Neuroimaging research is carried out in Magnetoencephalography, NMR spectroscopy, volumetrics, relaxometry, and new techniques such as water diffusion and blood flow MRI-based imaging. In addition, a growing research area of interest is outcome of epilepsy surgery.

Drug Trials, Clinical Trials, and the Epilepsy Phenome/Genome Project

The UAB Epilepsy Center has several Phase II, III and IV clinical trials in experimental drug protocols. In addition, neuropsychological cognitive side effects of antiepileptic drugs are being investigated. UAB is also participating with the EPGP project. You can read more about this study at UAB Participates in National EPGP Trial.

Magnetoencephalography (MEG):
UAB's MEG Lab also has a very active research program, lead by Dr. Robert Knowlton. Several studies have focused on the comparison of Magnetic Source Imaging (MSI) versus other neuroimaging modalities.

MSI (also known as MEG) is an advanced novel technology to noninvasively localize normal and abnormal brain function that can guide surgical decision-making. These two images represent Magnetic Source Imaging (MSI) results of patients with epilepsy and normal MRI.

MSI-image1 MSI_image2
MSI-image3