Several new options for patients with early and advanced Parkinson's disease are currently being investigated at UAB, while other therapeutic studies are targeting PD symptoms. In addition, researchers are involved in studies of a possible hereditary component of the disorder and potential disease markers in unaffected family members of Parkinsonian patients. A study involving dopamine-producing cell transplant therapy also is ongoing.
For information on UAB clinical trials currently recruiting PD patients, call 205-934-0683. UAB Insight will be covering these trials and others in more detail in future issues, as well as study results when they become available.
Confocal Immunofluorescent Micrograph of Human Cerebellum
Confocal immunofluorescent micrograph of normal human cerebellum showing the anatomical relationship between glial fibrillary acidic protein (red) and deiminated proteins (green). Co-localization (yellow) of these two markers is seen in numerous astrocytes (magnification 4X).
These are some interesting short videos showing the differences in normal mice vs. mice treated with MPTP and levodopa/carbidopa.