| Cystic Fibrosis Foundation Translational Research Center (CFTR) |
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Cystic Fibrosis Foundation Translational Research Center (CFTR)
 This Center has a core grant to develop a new biomarker for CFTR and is currently the central reading site for this CFTR biomarker. Dr. Steven Rowe is the international PI of the VX-809 study (targeting DF508 CFTR, the most common cause of CF) Dr. Steven Rowe is the Co-PI of the international study of PTC124 (targeting premature stop mutations in CFTR). This agent grew out of observations piloted by Dr. David Bedwell of UAB Microbiology. UAB was the top enrolling site in the recently completed Phase II study of VX-770 (targeting gating effects in CFTR). |