Clinical and Translational Studies: Office of Psychiatric Research

The Office of Psychiatric Clinical Research is designed to support psychiatric research in the clinical setting here at the Department of Psychiatry and Behavioral Neurobiology.  Our research division offers several cutting edge resources for Phase II, III and IV studies.  The coordination of our clinical trials is of the highest quality.  We are supported by experienced investigators and staff dedicated to academic excellence and quality patient care.  We have a full-time clinical research staff with regulatory and administrative services and assistance in designing clinical studies and providing referrals for statistical analysis.  We provide investigator training in psychiatric rating scales and standardized diagnostic instruments and education in patient recruitment.  We have a quality assurance program and facilities for drug storage, physical exams, EKG’s, interviewing, venipuncture and specimen processing. 

Our expert research team consists of:

Roberta May, MA, CCRC – Director; Hollis Ryan, BS, CCRC – Clinical Trials Manager; Samantha White, BS – Clinical Trials Administrator; Emily Bruer, M.Ed. – Clinical Trials Specialist; Nick Bossaller, BA – Clinical Trials Specialist; Rachel Chassan, M.S. - Research Assistant

Currently Enrolling Trials:

 Mood Disorders

" A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Once a Day, TAK-375 (Ramelteon) Tablet for Sublingual Administration (TAK-375SL Tablet) 0.1, 0.4, and 0.8 mg as an Adjunctive Therapy in the Treatment Acute Depressive Episodes Associated with Bipolar 1 Disorder in Adult Subjects (TAK375SL_201)" Principal Investigator: Richard Shelton, MD

" A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Once a Day, TAK-375SL 0.1, 0.4, and 0.8 mg as an Adjunctive Therapy to Treatment-as-Usual in the Maintenance Treatment of Bipolar 1 Disorder in Adult Subjects (TAK375SL_203)" Principal Investigator: Richard Shelton, MD

"Oxidative Stress Mechanisms in Mood Disorders" Principal Investigator: Richard Shelton, MD

""Early life origins of obesity: the relationships between early life stress and abdominal obesity in depressed patients" Principal Investigator: Li Li, MD, PhD

"Double-Blind, Proof-of-Concept (POC) Trial of Low Field Magnetic Stimulation (LFMS) Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (TRD) (Parent Study: Rapidly-Acting Treatments for Treatment Resistant Depression)" Principal Investigator: Richard Shelton, MD

"A 12-Week, Randomized, Double-Blind, Controlled Evaluation Followed by an Open-Label 12-Week Follow-up Period of the Impact of GeneSight Psychotropic on Response to Psychotropic Treatment in Outpatients Suffering from a Major Depressive Disorder (MDD) and Having Had - Within the Current Episode – an Inadequate Response to at Least One Psychotropic Medication Included in GeneSight Psychotropic" Principal Investigator: Richard Shelton, MD

"A Placebo-Controlled Crossover Study of Iloperidone Augmentation of SSRIs for Residual Anger and Irritability in Major Depressive Disorder" Principal Investigator: Richard Shelton, MD

"A double-blind, randomized, placebo controlled study to evaluate the efficacy and safety of intranasal esketamine for the rapid reduction of the symptoms of major depressive disorder, including suicidal ideation, in subjects assessed to be at imminent risk for suicide" Principal Investigator: Richard Shelton, MD

Other Enrolling Studies

"Circadian Misalignment in Shift Work Nurses" Principal Investigator: Karen Gamble, PhD

"Psychiatric Biological Samples Repository" Principal Investigator: Richard Shelton, MD

Healthy Volunteers

We have some studies that require Healthy Volunteers. Please contact us to find out what we have available.  

 

For further information, please contact:
UAB Department of Psychiatry
Office of Psychiatric Clinical Research
1720 7th Avenue South
Sparks Building, 10th Floor
Birmingham, AL 35294-0017
Telephone:  (205) 934-2484
Email: psychresearch@uab.edu