Our recent Kinomic Publications

  1. Kinase control of Latent HIV-1 Infection: PIM-1 Kinase as a Major Contributor to HIV-1 Reactivation. Duverger A, Wolschendorf F, Anderson JC, Wagner F, Bosque A, Shishido T, Jones J, Planelles V, Willey C, Cron RQ, Kutsch O. J Virol. 2013 Oct 23. [Epub ahead of print]. PMID: 24155393
  2. Kinomic profiling approach identifies Trk as a novel radiation modulator. Jarboe JS, Jaboin JJ, Anderson JC, Nowsheen S, Stanley JA, Naji F, Ruijtenbeek R, Tu T, Hallahan DE, Yang ES, Bonner JA, Willey CD. Radiother Oncol. 2012 Jun;103(3):380-7. PMID: 22561027

Abstracts

  1. Arafat WO, Anderson J, Welaya K, Willey C, Gillespie Y, Buchsbaum D. Triple Therapy Using Radiation Therapy (RT), Temozolomide (TMZ), and TRAIL Agonist (TRA-8) Enhances Cell Killing in Primary Glioma Cancer Stem Cells Associated With Changes in Distinct Tyrosine Kinase Signaling Cascades Identified Through Kinomic Analysis. International journal of radiation oncology, biology, physics. 2013;87(2):S140.
  2. G. Sonpavde, J.C. Anderson, K. Welaya, D. Chen, A. Mehta, P. Ghatalia, S. Sudarshan, W.E. Grizzle, T.K. Choueiri, C.D. Willey. Comprehensive activated kinase profiling to identify novel therapeutic targets in metastatic clear cell (cc)-renal cell carcinoma (RCC). Poster Presentation at the European Cancer Congress 2013.
  3. Huang Z-Q, Anderson J, Rohrbach, TD, Hall, SD, Brown RT, Julian BA, Willey CD, Novak J. Characterization of Signaling Pathways in Cultured Human Mesangial Cells Induced by IgA1-containing Immune Complexes from Patients with IgA Nephropathy. J. Am. Soc. Nephrol. 23, 824A, 2012.
  4. Anderson J, Duarte C, Naji F, Bouwmeester R, Rohrbach T, de wijn R, Willey CD. Kinomic Profiling Identifies Pathways of HER2 Targeted Therapy Resistance in HER2 Positive Breast Cancer Cell Lines. International Journal of Radiation Oncology* Biology* Physics 84 (3S), S23 (2012).
  5. Willey CD, Anderson JC, Duarte CW, Zhi D, Cui X, Choradia NV, Srinivasainagendra V, Wang J, Gillespie G. Kinomic Proband Model of Radiation Response from Patient-Derived GBM Xenolines. International Journal of Radiation Oncology* Biology* Physics 84, (3S) S178-9 (2012).
  6. Lerma L.A., Anderson J.C., Xu C., Kao M., Kim K.H., MS, Annis J., Rohrbach T.D., Grandori C., Willey C.D., Méndez E. Kinome profiling identifies novel therapeutic targets in p53-mutant, metastatic head and neck squamous cell carcinoma. Oral Presentation at the 8th International Conference on Head and Neck Cancer, July 2012.
  7. Huang Z-Q, Anderson J, Hall, SD, Rohrbach, TD, Brown RT, Julian BA, Willey CD, Novak J. Immune Complexes from Patients with IgA Nephropathy Containing Galactose-Deficient IgA1 and Anti-glycan Antibodies Induce Protein-kinase Signaling and Proliferation in Cultured Human Mesangial Cells. J. Am. Soc. Nephrol. 22, 531A, 2011.
  8. Gillespie, G.Y., Duarte, C.W., Willey, C.D., Zhi, D., Cui, X., Anderson, J.C., Yamshchikov, V., Langford, C., Mehta, T., Srinivasasainagendra, V., Wang, J., Sambandam, V., Thottassery, J.V. Integrated ‘Omics of Patient-Derived GBM Xenolines: Proband Models For Personalized Medicine. SAIC/NCI GBM Workshop, September 2011.
  9. Huang Z-Q, Anderson J, Hall, SD, Rohrbach, TD, Brown RT, Julian BA, Willey CD, Novak J. Protein-kinase Inhibitors Can Block Cellular Proliferation and Signaling Induced in Cultured Human Mesangial Cells by Immune Complexes from Patients with IgA Nephropathy. J. Am. Soc. Nephrol. 22, 531A, 2011.
  10. Willey CD, Tu T, Jaboin J, Ruijtenbeek R, Hallahan DE: Kinomic analysis identifies trk as a target for modulation of radiation sensitization in vascular endothelium. International Journal of Radiation Oncology Biology Physics 72:S62-S62, 2008.