Richard Reynolds IV, PhDAssistant Professor



1720 2nd Avenue S
Shelby Building, room 211
Birmingham, AL 35294-2182

Telephone:(205) 975-9300




Rhodes College, 1996
M.Sc.: Texas State University, 2000
Ph.D.: University Of Maryland, College Park, 2008
Postdoctoral Fellow: University of Alabama at Birmingham, 2010


Research Interests

My research interests are to identify genetic, epigenetic and transcriptomic features that implicate important biological pathways causing inflammatory diseases. My research is highly cross disciplinary including areas of study such as clinical science, epidemiology, statistical genetics, immunology and evolution. The approaches I use sometimes require sophisticated statistical approaches with large computational burden. In addition to statistical methods application I also develop methods when appropriate. I am working currently to discover the molecular and environmental features that are important for gout pathogenesis. The ultimate goal of the research is to make use of computational tools and data resources, both large and small, and the kind willingness of people to participate in research, to increase our knowledge of complex inflammatory diseases.



Click here for a more complete list of publications. A few selected papers are below.

Reynolds RJ, Vazquez AI, Srinivasasainagendra V, Klimentidis YC, Bridges SL Jr, Allison DB, Singh JA. 2016. Serum urate gene associations with incident gout, measured in the Framingham Heart Study, are modified by renal disease and not by body mass index. Rheumatol Int. 36(2):263-70. PMID: 26427508; PMCID: PMC4724568.

Reynolds RJ, de Los Campos G, Egan SP, Ott JR. 2016. Modelling heterogeneity among fitness functions using random regression. Methods Ecol Evol. 7(1):70-79. PMID: 26949509; PMCID: PMC4776641.

Reynolds RJ, Ahmed AF, Danila MI, Hughes LB; 2014. Consortium for the Longitudinal Evaluation of African Americans with Early Rheumatoid Arthritis Investigators, Gregersen PK, Raychaudhuri S, Plenge RM, Bridges SL Jr. HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: hierarchical classification systems, amino acid positions, and residues. Arthritis Rheumatol. 66(12):3274-82.  PMID: 25524867; PMCID: PMC4273668.