CLEAR I

Longitudinal Arm

CLEAR II

Cross-Sectional Arm

• Self-reported African American race/ethnicity
• RA for < 2 years disease duration at study entry, meeting ACR Criteria
• Age 19 or older
• African-American controls matched for sex, age, geographic location

• Self-reported African American race/ethnicity
• RA diagnosis at study entry, meeting ACR Criteria
• Age 19 or older
• African-American controls matched for sex, age, geographic location and
  disconfirmed for RA, Lupus, and other connective tissue autoimmune disease.

• Database: Baseline demographic, clinical, and socioeconomic information
• Radiographic data*
• Genomic DNA
• Serum and plasma (limited amounts)

* 300 RA patients at baseline (<2 years disease duration)

175 RA patients at baseline (3 years disease duration)

110 RA patients at baseline (5 years disease duration)

• Database: Baseline demographic,clinical, and socioeconomic information
• Radiographic data*
• Genomic DNA
• Serum and plasma (limited amounts)

* 500 RA patients at various disease durations