Clinical Trials

researchUAB 0664 -   This is a randomized study to assess the efficacy of performing swallowing exercises during radiation treatment vs. starting these exercises at the completion of radiation therapy for patients with head and neck cancer.

PI: William Carroll, MD

 

UAB 0718 -   This is a phase 2 trial to assess whether Erlotinib (Tarceva) is effective in preventing subsequent recurrence for patients who have undergone salvage surgery for head and neck cancer that came back after completion of radiation. 

PI: Eben Rosenthal, MD

UAB 0842 -   This a phase 3 study assessing the use of the drug Lymphoseek® to help indentify affected lymph nodes in patients undergoing surgery for skin or mucosal head and neck squamous cell carcinoma. 

PI: William Carroll, MD

UAB 0913 -   This is a phase 1 study to evaluate the safety and pharmacokinetics of a new treatment (Ad/PNP-F-araAMP) in patients with advanced solid tumors that have failed standard treatment. This is a dose escalating study consisting of 4 cohorts with 3 subjects in each cohort. 

PI: Eben Rosenthal, MD

UAB 0964 -   This is a phase 2 randomized study assessing the use of Pioglitazone (which is a standard medication used for diabetes) in patients with oral lesions that are premalignant. Patients will be randomized to the use of Pioglitazone vs. placebo. 

PI: Eben Rosenthal, MD

UAB 1007 -   This is a study to assess the use of a contrast agent for patients with solitary thyroid nodules requiring an ultrasound and fine needle aspiration. This agent will be used in hopes to better identify malignancy. 

PI: Glenn Peters, MD