Jayme E. Locke, MD, MPH

locke  Jayme E. Locke, MD, MPH
Assistant Professor of Surgery, Abdominal Transplant Surgery
Director, Incompatible Kidney and Kidney Paired Donation Programs
Director, CTI Outcomes Research Center

Lyons-Harrison Research Building, 748
1720 2nd Avenue South
Birmingham, AL 35294

Phone: 205-934-2131

Board Certification  

General Surgery, American Board of Surgery
Abdominal Transplant Surgery, ASTS Fellowship Trained

 

Areas of Interest 

Incompatible kidney transplantation & kidney paired donation
Kidney transplantation in HIV-positive patients
Disparities in access to and outcomes after kidney transplantation

 

Education

08/94 – 05/98 BS Duke University
08/98 – 05/02 MD East Carolina University
07/02 – 06/10 Residency Johns Hopkins Hospital
07/05 – 06/08 Research Johns Hopkins University Comprehensive Transplant Center
07/06 – 05/07 MPH Johns Hopkins University Bloomberg School of Public Health
07/10 – 06/12 Fellowship Johns Hopkins Hospital

 

Society Memberships

American College of Surgeons (ACS) (candidate)
American Society of Transplantation (AST)
American Society of Transplant Surgeons (ASTS)

 

Awards and Honors

1994:  United States Army Reserve National Scholar Athlete
1994 – 1998:  Mary Crawford Norwood Scholarship
1995:  Phi Eta Sigma National Honor Society
1996:  Rockefeller University, Research Fellow
1997:  Carolinas and Ohio Science Education Network Research Fellow
1997 – 1998:  Duke University Quadrangle Council Representative
1998:  Cum laude, Duke University
1998 – 2002:  Brody Scholar, Full Academic Scholarship, East Carolina Univ. School of Medicine
1998 – 2002:  East Carolina University Bookstore Scholarship
2000:  Medical Student Council Representative
2001:  Alpha Omega Alpha
2002:  Frank Longino, M.D. Most Outstanding Medical Student in General Surgery Award
2006:  ASTS 2006 Winter Symposium Top Ten Abstracts Travel Award
2007:  Baltimore Academy of Surgery Resident Research Award
2007:  Canadian Society of Transplantation Top Ten Abstract Award
2007:  ASTS 2007 Winter Symposium Top Ten Abstract Award
2007:  Johns Hopkins Bloomberg School of Public Health Capstone Award for most outstanding Masters of Public Health thesis
2007:  Johns Hopkins University, Department of Surgery, Gershon T. Efron Award for Excellence in Clinical Research
2007:  Johns Hopkins University Comprehensive Transplant Center, Science of Hope – Medicine of Compassion Award Nominee
2008:  Johns Hopkins University, Department of Surgery, Poster Research Day, 1st Prize Basic Science  
2008:  Johns Hopkins University, Department of Surgery, Gershon T. Efron Award for Excellence in Clinical Research
2008:  Johns Hopkins University, Department of Surgery, Ravitch Award for Excellence in Scientific Writing
2009:  ASTS 2009 Winter Symposium Top Ten Abstract Award
2009:  Genzyme Annual Fellows Conference Clinical Science Award
2009 – 2010: Administrative Chief Resident, Johns Hopkins University, Department of Surgery
2010:  Johns Hopkins University, Department of Surgery, Core Values Award
2010:  Johns Hopkins University, Department of Surgery, John L. Cameron Technical Excellence Award
2012:  University of Alabama at Birmingham Minority Health and Health Disparities Research Center, Health  Disparities Research Training Award Program Scholar
2013:  ASTS 2013 Winter Symposium Top Ten Abstract Award
2013:  American Transplant Congress 2013 – Young Investigator Award

 

Selected Publications

Locke JE, Zachary AA, Haas M, Melancon JK, Warren DS, Simpkins CE, Segev DL, Montgomery RA.  The utility of splenectomy as rescue treatment for severe acute antibody mediated rejection.  Am J Transplant.  2007; 7(4): 842-846.

Locke JE, Segev DL, Warren DS, Dominici F, Simpkins CE, Montgomery RA.  Outcomes of kidneys from donors after cardiac death:  implications for allocation and preservation.  Am J Transplant.  2007 7(7): 1797-1807.

Segev DL, Simpkins CE, Thompson RE, Locke JE, Warren DS, Montgomery RA.  Obesity impacts access to kidney transplantation.  J Am Soc Nephrol.  2007; 19(2): 349-355.

Locke JE, Warren DS, Dominici F, Cameron AM, Leffell MS, McRann DA, Melancon JK, Segev DL, Simpkins CE, Singer AL, Zachary AA, Montgomery RA.  The influence of donor ethnicity on outcomes following deceased donor kidney transplantation in black recipients.  J Am Soc Nephrol.  2008; 19(10): 2011-2019.

Locke JE, Warren DS, Dominici F, Cameron AM, Leffell MS, McRann DA, Melancon JK, Segev DL, Simpkins CE, Singer AL, Zachary AA, Montgomery RA.  The influence of donor ethnicity on outcomes following deceased donor kidney transplantation in black recipients.  J Am Soc Nephrol.  2008; 19(10): 2011-2019.

Locke JE, Singer AL, Segev DL, Haas M, Hillel AT, King KE, Kraus E, Lees LM, Melancon JK, Stewart ZA, Warren DS, Zachary AA, Montgomery RA.  The use of antibody to complement protein C5 for salvage treatment of severe antibody mediated rejection.  Am J Transplant.  2009; 9(1):  231-235.

Locke JE, Montgomery RA, Warren DS, Subramanian A, Segev DL.  Renal transplantation in HIV-positive recipients:  long-term outcomes and risk factors for graft loss.  Archives of Surgery.  2009; 144(1):  83-86.

Montgomery RA, Locke JE, King KE, Segev DL, Warren DS, Kraus ES, Cooper M, Simpkins CE, Singer AL, Stewart ZA, Melancon JK, Ratner L, Zachary AA, Haas M.  ABO incompatible renal transplantation:  a paradigm ready for broad implementation.  Transplantation.  2009; 87(8): 1246-1255.

Stewart ZA, Locke  JE, Montgomery RA, Singer AL, Cameron AM, Segev DL.  ABO-incompatible deceased donor liver transplantation in the United States: a national registry analysis.  Liver Transplant.  2009; 15(8): 883-893.

Locke JE, Zachary AA, Warren DS, Segev DL, Houp JA, Montgomery RA, Leffell MS.  Proinflammatory events are associated with significant increases in breadth and strength of HLA-specific antibody.  Am J Transplant.  2009; 9(9): 2136-2139.

Melancon JK, Kucirka LM, Boulware LE, Powe NR, Locke JE, Montgomery RA, Segev DL.  Impact of Medicare coverage on disparities in access to simultaneous pancreas and kidney transplantation.  Am J Transplant.  2009; 9(12): 2785-2791.

Allen G, Simpkins CE, Segev D, Warren D, King K, Taube J, Locke JE, Baldwin W, Haas M, Chivukula R, Montgomery RA. Rapid accommodation of an A1 renal allograft after preconditioning for ABO-incompatible transplantation. Contrib Nephrol. 2009;162:35-46

Montgomery RA, Lonze BE, King K, Kraus E, Kucirka L, Locke JE, Warren DS, Simpkins CE, Dagher NN, Singer AL, Zachary AA, Segev DL.  Desensitization in HLA-incompatible kidney recipients and survival. New Engl J Med, 2011; 365(4): 318-326.

Jordan SC, Locke JE, Montgomery RA.  Desensitization protocols for crossing human leukocyte antigen and ABO incompatible barriers.  Current Opinion in Organ Transplantation.  2007; 12: 371-378.

Locke JE and Segev DL.  Renal transplantation in HIV-positive recipients.  Current Infectious Disease Reports, 2010; 12(1): 71-75.