Research - News
UAB researchers have published an article demonstrating how the term “aggressive care,” used loosely by clinicians to describe care that can negatively impact quality of life for patients with serious illness, is often used to inappropriately label the preferences of African American patients.
Experimental neonatal chronic lung disease is marked by a redox imbalance that damages the lungs, and that damage can be ameliorated using a live biotherapeutic mixture of three Lactobacillus species.
Grants totaling more than $3 million have been awarded to UAB researchers in Chemistry and Physics by the Department of Energy, signaling continued investment in UAB projects.
In this cohort study of 19,580 patients with breast cancer, the researchers found that White women who lived in less deprived neighborhoods showed decreased mortality, but that Black women did not.
A UAB study including more than 20,000 ventricular assist device recipients showed that patients diagnosed with familial dilated cardiomyopathy had better clinical outcomes compared with other DCM diagnoses.
This finding suggests utility of treatments before fecal microbial transplants to reduce recipient microbial communities. This would help donor microbial strains dominate in the recipient.
The gift will advance the use of induced pluripotent stem cells as a potential therapy for Alzheimer’s disease.
Experiments reveal that a catalytic subunit of CK2, called CK2α, is an important regulator of mouse CD8+ T cell activation, metabolic reprogramming and differentiation, both in vitro and in a mouse-infection model by the intracellular pathogen Listeria monocytogenes.
At their annual Innovation Awards, UAB’s Bill L. Harbert Institute for Innovation and Entrepreneurship celebrated innovators from all corners of campus for their accomplishments, inventions and ingenuity.
Gould’s helmet research added variables such as fall height and the type of surface struck.
The funding will be used to purchase cutting-edge equipment to assist with high-containment research productivity and pandemic preparedness at UAB.
Insights gained from this project can lead to a new understanding of the mechanisms by which human deep-brain activity gives rise to cognitive-emotional behaviors, such as social thought processes, impulsivity and affect.
Direct reprogramming is a potential therapy for heart attack patients. In vitro, TBX20 improved contractility and mitochondrial function of reprogrammed heart muscle cells.
Diseases linked to atherosclerosis are the leading cause of death in the United States.
The new, one-of-a-kind center has a vision of improving the health and function of people with disabilities through encouraging access, increasing participation, and promoting adherence to recreation, exercise and sports.
UAB Nutrition researchers are investigating whether calorie restriction or intermittent fasting can slow the aging process.
A four-year grant from NIH will fund a clinical trial that will test new approaches to cognitive rehabilitation in adults with stroke.
Given the rising rates of obesity and diabetes, semaglutide could be used effectively to reduce the burden of these chronic diseases.
New funding will advance research on the role of diet and race in knee arthritis pain and pain sensitivity, respectively, in transgender community.
The study will examine a protein that may help slow bleeding in the brain when given within a two-hour window following the first signs of hemorrhage.
The UAB Marnix E. Heersink School of Medicine leadership team outlined key research focus areas to ensure continued growth over the next five to seven years.
This novel finding will help guide successful therapeutic design and strategies for acute kidney injury and chronic kidney disease.
Knockout of TXNIP improves diabetes-associated hyperglycemia and hyperglucagonemia.
Published results suggest the COVID-19 pandemic exacerbated the slow increase in pediatric Type 2 diabetes.
New research seeks to navigate therapeutic resistance for glioblastoma, a type of a severe brain cancer.
The clinically approved drug ruxolitinib suppressed a mouse model of melanoma that is resistant to immune checkpoint blockers.
The UAB projects will investigate was to improve and increase the use of artificial intelligence in biomedical research.
Owsley and McGwin will lead three data collection sites in the collection of data to inform machine learning approaches to provide critical insights into the endemic condition Type 2 diabetes mellitus.
The study, an exception from informed consent trial, will compare whole blood to blood components in the treatment of traumatic injuries.
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