Jeff Hansen

Jeff Hansen

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Research Editor

jeffhans@uab.edu • (205) 209-2355

Communicates UAB research discoveries and initiatives from across the university for a variety of audiences.

Specific beats include: biochemistry; cell, developmental and integrated biology; microbiology; molecular genetics; neurobiology; pathology; pharmacology and tocixology; Alabama Drug Discovery Alliance; Bill L. Harbert Institute for Innovation and Entrepreneurship.

A microRNA network is the putative mediator of reductive stress in the heart

Understanding how reductive stress is controlled may help personalize treatment of heart failure patients, leading to better outcomes.

Understanding how reductive stress is controlled may help personalize treatment of heart failure patients, leading to better outcomes.

Ovarian cancer: potential therapeutic target identified

The histone methyltransferase DOT1L — the potential target — is overexpressed in ovarian cancer, and high levels of expression correlate with reduced progression-free and overall survival.
The histone methyltransferase DOT1L — the potential target — is overexpressed in ovarian cancer, and high levels of expression correlate with reduced progression-free and overall survival.

First 3-D view of TB granulomas alters paradigm of their shape and formation

MicroCT of infected human lung tissue, along with histology and immunohistochemistry, was used to construct images of TB granulomas, airways and vasculature.

MicroCT of infected human lung tissue, along with histology and immunohistochemistry, was used to construct images of TB granulomas, airways and vasculature.

Advantages of intranasal vaccination against SARS-CoV-2

Intranasal vaccination is needle-free and elicits immunity at the site of infection, the respiratory tract.
Intranasal vaccination is needle-free and elicits immunity at the site of infection, the respiratory tract.

A small molecule induces readthrough of cystic fibrosis CFTR nonsense mutations

This research suggests that a path to treat currently untreatable cases of cystic fibrosis is clearly achievable.
This research suggests that a path to treat currently untreatable cases of cystic fibrosis is clearly achievable.

Melanoma of the eye: preclinical tests show path toward treatment

A small molecule inhibitor has been identified that reduces the growth of uveal melanoma, a rare and deadly cancer of the eye.
A small molecule inhibitor has been identified that reduces the growth of uveal melanoma, a rare and deadly cancer of the eye.

Bjornsti named to national role — vice president for Science Policy at FASEB

The largest coalition of biological and biomedical research associations in the United States, known as FASEB, advocates for the basic biomedical research community. (Photo by: Steve Wood)

The largest coalition of biological and biomedical research associations in the United States, known as FASEB, advocates for the basic biomedical research community.

S. pneumoniae sticks to dying lung cells, worsening secondary infection following flu

This novel virulence trait, which increases severity of S. pneumoniae superinfection, involves pneumococcal surface protein A, now identified as an adhesin.
This novel virulence trait, which increases severity of S. pneumoniae superinfection, involves pneumococcal surface protein A, now identified as an adhesin.

Undiagnosed and untreated disease identified in rural South Africa

A comprehensive health-screening program in rural northern KwaZulu-Natal has found a high burden of undiagnosed or poorly controlled non-communicable diseases. (Photo by: Africa Health Research Institute)

A comprehensive health-screening program in rural northern KwaZulu-Natal has found a high burden of undiagnosed or poorly controlled non-communicable diseases.

Will reduction in tau protein protect against Parkinson’s and Lewy body dementias?

New results suggest the answer is no, implying that the role of tau in the pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease.
New results suggest the answer is no, implying that the role of tau in the pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease.
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