'Biggest Loser' Winner Rachel Frederickson Raises Questions About Healthy Weight Loss

Weight loss as rapid as Frederickson's could result in a loss of bone mass and an increase in bone marrow fat, explained assistant professor Krista Casazza, Ph.D., R.D., which might set a person up for cardiovascular problems like heart attacks and high blood pressure, as well as increased risk of fractures. Casazza is an expert on body tissue partitioning (the interplay between fat, bone and muscle) at the University of Alabama at Birmingham.