Eye Study Advances Ability to Improve Clinical Measurement of Retinal Degeneration
by Traci Bratton
University of Alabama at Birmingham (UAB) researchers studying rod cell proteins GARP1 and GARP2, or glutamic acid-rich proteins 1 and 2, to learn how they function in normal phototransduction in the eye have found that GARP2 accelerates retinal degeneration in mice that lack another rod cell protein, cyclic guanosine monophosphate (cGMP)-gated cation channel β-subunit, involved in producing the electrical signal.