UAB researcher Andra Frost, M.D., associate professor in the Department of Pathology and scientist in the Experimental Therapeutics Program of the UAB Comprehensive Cancer Center, has been awarded a Susan G. Komen for the Cure research grant for $600,000 to study the role of the oncogene Gli1 in the metastasis of triple negative breast cancer, an especially aggressive subtype of the disease. An oncogene is a gene that has the potential to cause cancer. In tumor cells, they are often mutated or expressed at high levels. Gli1 is known to regulate the presence of a variety of molecules that are important for cancer development, growth and metastasis. It mostly has been studied in skin and brain cancers, but its role in other cancers, such as breast cancer, is less established. Frost is hoping to understand how Gli1 is promoting the metastasis of triple negative breast cancer. Currently there are no widely used targeted therapies for the treatment of triple negative breast cancer. Ultimately, Frost says, “We want to show that inhibiting the function of the Gli1 will slow or stop the growth and metastasis of triple negative breast cancer.”
Four new NSF grants — three in neuroscience — deepen UAB’s research portfolio, forge collaborationsAlabama now has more EPSCoR Track II grants than any other state following the award of basic science grants meant to stimulate competitive research in regions of the country traditionally less able to compete for such research funds.posted yesterday 244 viewsUAB ranked 18th nationally in research funding among public universitiesUAB secured more than $328.5 million in federal research funding in 2015, ranking the institution No. 18 among public universities and No. 34 overall in the United States during a year in which UAB’s total research and development expenditures exceeded $516 million.posted 7 days ago 2715 viewsMaster’s candidate at UAB receives International FellowshipA prestigious fellowship from the American Association of University Women has been awarded to a UAB graduate student.posted 8 days ago 1631 viewsUAB case study chronicles first brain bleed tied to energy drinksUAB neurologists have reported the first case study of a patient with a brain bleed linked to consumption of an energy drink.posted 15 days ago 10666 viewsUAB study finds yoga is relatively safe, but know your limitsA UAB study says the rate of yoga-related injuries is going up, especially in older participants.posted 19 days ago 1812 viewsBlazer Innovation Challenge student winners announced in “Shark Tank”-style competitionBiomedical engineering student Forrest Satterfield received $5,000 to help launch his 3-D-printed prosthetics idea.posted 19 days ago 1552 viewsUAB names vice president of Research after national search
Christopher S. Brown, Ph.D., former vice president of Research for the University of North Carolina System and director and primary investigator of the NASA/North Carolina Space Grant, tapped to grow UAB’s $500 million annual research portfolio.International HIV symposium comes to BirminghamScientists from around the world will gather at UAB in December to focus on HIV research and women, particularly collaborative research on women living with HIV and those at risk.
How a Mediterranean-style diet may reduce heart failure in the agedA Western-style diet, with more omega-6 fatty acids than the Mediterranean, dysregulates lipid signaling in aged mice and promotes inflammation.posted 21 days ago 3111 viewsSimple genetic test shows promise for better outcomes in heart stent patientsThe power and promise of personalized medicine: a genetic test can reduce cardiovascular risk for some heart patientsposted 22 days ago 2388 viewsUAB receives grant to better serve those with autism spectrum disorder in central AlabamaAlabama Interagency Autism Coordinating Council has established regional networks throughout Alabama to centralize resources for those with autism spectrum disorder, and for their families.posted 23 days ago 6639 viewsHow internal circadian clocks in neurons encode external daily rhythms of excitabilityA mechanism through which circadian clocks in neurons encode external daily rhythms of excitability allows pacesetter neurons to communicate with the rest of the body via electrical impulses, with possible implications in understanding and treating mood disorders.posted 23 days ago 2428 viewsAntibody suppresses HIV in infected individualsAntibody VRC01 proves safe for individuals infected with HIV-1 but only modestly controls the virus in participants who stop receiving antiretroviral therapy.posted 28 days ago 3884 viewsAlzheimer’s disease family caregivers will get telemedicine trainingA UAB study will test whether training to modify care-resistant behavior can improve quality of life for family caregivers of dementia patients.posted a while back 2390 viewsUAB/Auburn study will test new MRI technique for epilepsyUAB and Auburn will team up for a study of magnetic resonance imaging techniques that could enhance epilepsy surgery.posted a while back 3115 viewsUAB vaults 36 spots in U.S. News & World Report’s Best Global UniversitiesU.S. News & World Report ranks UAB No. 162 in its 2017 Best Global Universities ranking, up from its rank of No. 200 in 2016 and 269 spots higher than the next-highest-ranked university in Alabama.posted a while back 12870 viewsUAB researchers receive grant to study effects of Cialis on halogen gas-induced injury in pregnant womenUAB researchers hope to establish Cialis as a therapeutic agent for pregnant women exposed to chlorine and bromine during industrial accidents or acts of terrorism.posted a while back 2123 viewsVaccination of newborn mice with bacteria suppresses asthma as adultsThis study of cockroach-induced asthma and Enterobacter mirrors previous studies with fungus- and house dust mite-induced asthma, where neonatal vaccination with bacteria suppressed adult asthma.posted a while back 3947 viewsSilent auction and wine tasting to support UAB scholarships on Nov. 6UAB Alumni Society hosts its annual silent auction to raise money for UAB Scholarships.
- Event Date December 6
New study compares different approaches for stroke prevention in patients with non-valvular atrial fibrillationUAB doctors say stroke prevention treatments are not one-size-fits-all, and treatment options can be individualized using this hierarchical ranking.posted a while back 2022 views
- Event Date November 6