UAB researcher Andra Frost, M.D., associate professor in the Department of Pathology and scientist in the Experimental Therapeutics Program of the UAB Comprehensive Cancer Center, has been awarded a Susan G. Komen for the Cure research grant for $600,000 to study the role of the oncogene Gli1 in the metastasis of triple negative breast cancer, an especially aggressive subtype of the disease. An oncogene is a gene that has the potential to cause cancer. In tumor cells, they are often mutated or expressed at high levels. Gli1 is known to regulate the presence of a variety of molecules that are important for cancer development, growth and metastasis. It mostly has been studied in skin and brain cancers, but its role in other cancers, such as breast cancer, is less established. Frost is hoping to understand how Gli1 is promoting the metastasis of triple negative breast cancer. Currently there are no widely used targeted therapies for the treatment of triple negative breast cancer. Ultimately, Frost says, “We want to show that inhibiting the function of the Gli1 will slow or stop the growth and metastasis of triple negative breast cancer.”
Youth’s use of technology drives home need for evolution in distracted walking, bicycling and driving policiesDistractions from technology have a detrimental effect on children’s crash risk as pedestrians and drivers.posted yesterday 134 viewsStudy shows navigation program improves longevity of care for youth with HIV in AmericaAdherence to care improves when youth with HIV receive education and help navigating the system, according to study out of UAB.posted yesterday 150 viewsExtreme preterm infant death or disease may be predicted by biomarkerA biomarker, endothelial mitochondrial function, may be useful for early identification of newborn babies at risk for lung disease and could enable novel therapy approaches.posted yesterday 159 viewsWells Fargo gifts advance growth for Collat School of Business and UAB AthleticsGifts established a scholarship program for business students and support the new Football Operations building fund.posted 7 days ago 1246 viewsUAB again ranks high in NIH fundingFunding to UAB for medical research by the National Institutes of Health topped $238 million in 2016, driving innovation and growth.posted 6 days ago 2337 viewsUAB clinical trials pave way to new cystic fibrosis drugSuccessful Phase III trials at UAB contributed to the development of a novel “corrector-potentiator” combination drug therapy for cystic fibrosis patients.posted 8 days ago 4426 viewsGirls In Science and Engineering Day to be held May 13Local middle school girls will come to UAB to participate in fun science and engineering activities led by female students and professionals.
UAB back surgery quality scores top national averagesUAB neurosurgery’s commitment to quality care is reflected in outcomes that beat national averages in key measurements.posted 18 days ago 1546 viewsFirst students graduate from Innovate Birmingham Regional Workforce Partnership InitiativeSome of the 18 graduates of the Innovate Birmingham Workforce Program have been offered jobs to begin high-demand information technology careers with local employers like Blue Cross and Blue Shield of Alabama, Brasfield & Gorrie, Regions and UAB.posted 18 days ago 2157 viewsFixing broken hearts through tissue engineeringA UAB symposium on cardiovascular tissue engineering brought together some of the best in the business in this rapidly developing field of translational medicine.posted 18 days ago 2250 viewsUAB spinoff targets cancer with drug-resistant immunotherapy, a novel approach to fighting tumorsThe first target for the UAB spinoff Incysus Ltd. will be glioblastoma. Incysus has just received a European patent for its innovative approach to fighting cancer.posted 19 days ago 1396 viewsPollock labs awarded more than $11 million to study renal control of sodium and salt balanceThe five-year grant from the NHLBI to the labs of Jennifer and David Pollock also includes a third project at the University of Utah, bringing together three highly successful research entities.posted 20 days ago 3158 viewsSleepy drivers make dangerous drivers: how to stay awake behind the wheelKnowing the signs of becoming drowsy behind the wheel, many of which are similar to distracted and drunk driving, could potentially be lifesaving.posted 21 days ago 2612 viewsUAB to host Mad Scientist DayKids can partake in more than 30 interactive demonstrations and learn basic principles of science while having fun.
- Event Date May 13
Mice with missing lipid-modifying enzyme heal better after heart attackKnowledge from this study and others may help physicians boost healing and prevent heart failure in patients after a heart attack.posted 22 days ago 2307 viewsSurgeons utilizing more organs for transplant a year after AOC’s Donor Recovery Center openingA record year for deceased organ donors included more than doubling the number of lungs donated at UAB.posted 26 days ago 10518 viewsBlazer Motorsports launches crowdfunding effort to send Baja team to national competitionAn interdisciplinary team that includes Engineering, the Collat School of Business, and the College of Arts and Sciences is reaching for new heights to make UAB’s team a perennial contender.posted 28 days ago 1561 viewsParadigm-changing clinical trial underway to better identify ureter during pelvic surgeryNew dye could help better identify ureter, the passage between kidney and bladder, and prevent injury during minimally invasive pelvic surgery for women.posted 28 days ago 1896 viewsAHA awards UAB a $3.7 million grant to further generational obesity researchA multidisciplinary research team at UAB looks to address obesity as it is genetically passed from mother to child.posted 29 days ago 2641 viewsGrant will boost research and training in the fight against lung diseaseAs lung diseases worsen worldwide, UAB has launched a pre-doctoral training program in pulmonary research that will focus on lung diseases such as asthma, cancer, COPD, cystic fibrosis, pneumonia, lung injury and idiopathic pulmonary fibrosis.posted 29 days ago 1367 views
- Event Date May 6