Displaying items by tag: department of pathology
Insights that are not possible with conventional two-dimensional platforms include characterization of obliterated airways in tuberculosis and hemorrhage from ruptured blood vessels in COVID-19 lungs, at near-microscopic levels.
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Experiments reveal that a catalytic subunit of CK2, called CK2α, is an important regulator of mouse CD8+ T cell activation, metabolic reprogramming and differentiation, both in vitro and in a mouse-infection model by the intracellular pathogen Listeria monocytogenes.
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The funding will be used to purchase cutting-edge equipment to assist with high-containment research productivity and pandemic preparedness at UAB.
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Diseases linked to atherosclerosis are the leading cause of death in the United States.
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The funding from the Norma Livingston Ovarian Cancer Foundation will help further ovarian cancer research to advance therapeutic treatments.
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O’Neal Invests funds UAB investigators initiating new cancer-related projects to do key preliminary work to enable competitive extramural applications.
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UAB patients who meet the criteria to be tested can talk to their physician about obtaining a test.
The researchers found that ARID1A-deficient bladder cancers are sensitive to combination therapies with the EZH2 inhibitor and inhibitors of PI3K, in a synergistic manner.
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These changes, seen in a mouse model, are a likely proteome signature for reductive stress cardiomyopathy. About one in six heart failure patients shows reductive stress, according to a 2018 clinical study.
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The creation of the division stands to help emphasize the UAB Department of Pathology’s commitment to women’s health.
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The Council on Basic Cardiovascular Sciences, known as the BCVS, is one of the largest councils at the American Heart Association, and it is one of the largest organizations in cardiovascular sciences globally, with more than 4,700 members.
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To facilitate gene-level queries of data from more than 10,000 cancer patient transcriptome sequences and proteomics data from 2,000 patients, researchers have developed a user-friendly cancer data analysis web platform called UALCAN.
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For just the third time in history, a University of Alabama at Birmingham faculty member has been elected to the prestigious National Academy of Sciences.
Blood supplies continue to be low nationwide.
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Researchers show how two types of immune cells — one a part of the innate immune system and the other a part of the adaptive immune system — play distinct and indispensable roles in the colon to defend against pathogenic bacteria.
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Join UAB’s O’Neal Comprehensive Cancer Center to learn about the rare blood cancer multiple myeloma.
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The grant will fund research surrounding next-generation human models that could potentially aid in the development of treatment for glioblastoma.
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Blacks face much greater rates of heart disease than do whites. A wider study is needed to further investigate this racial difference and identify potential therapeutic targets.
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In response to a viral infection, intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling, leading to different fates for two subsets of those cells — the one producing IL-2 and the one not producing IL-2.
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Blood supplies continue to be low nationwide.
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