According to Bruce Korf, M.D., Ph.D., chair of the department of genetics, and director of the Heflin Center for Genomic Sciences at the University of Alabama at Birmingham, the glut of genetic information that will be used to inform treatment decisions will require additional education of clinicians, especially since a sizable cohort received their genetics training before the genomic age.
"If someone has hepatitis C and does not know it, it could be doing damage to their liver," says Michael Saag, MD, professor of medicine and director of the Center for AIDS Research at the University of Alabama at Birmingham. He is also co-chair of the Infectious Diseases Society of America's HCV Guidance panel.
However, the results show a significant increase in maternal mortality for women who live greater distances from the hospital, according to the study Dr Michael Froelich of University of Alabama at Birmingham (UAB) and colleagues. The findings point to differences in health care access as a possible explanation for racial differences in pregnancy-related death in the United States.
The original face of AIDS was that of a middle-class, often white, gay man living in New York or San Francisco. That picture has changed over time as people of color have become disproportionately affected by the epidemic. Today, the face of AIDS is Black or Latino, poor, often rural - and Southern.
Dr. Trygve Tollefsbol, director of the Cell Senescence Culture Facility at the University of Alabama at Birmingham, said the study "provides a unique way of looking at aging not only in terms of aging of the liver but also in terms of epigenetic aging." The findings are important because a liver that ages more quickly may make a person more likely to develop cancer, Tollefsbol added.