The drug inhibits the activity of a kinase enzyme called LRRK2, and it showed no pathology in rat lungs, kidneys or livers.
Use of a risk characterization approach served as an indirect way to contextualize the safety profile of Xeljanz, a Janus kinase inhibitor, in patients with rheumatoid arthritis vs. the safety profile of tumor necrosis factor-alpha inhibitors, according to research.
For a large number of participants in these "open-label" placebo trials, knowing that their "treatment" is an inert pill doesn't stop them from feeling relief.
Ten weeks of intensive reading intervention for children with autism spectrum disorder was enough to strengthen the activity of loosely connected areas of their brains that work together to comprehend reading, researchers have found.
At the University of Alabama at Birmingham Alzheimer's Risk Assessment and Intervention Program, if you are between 45 and 65 you can get an assessment and walk away with a numerical estimate of your chances for developing dementia within the next 20 years.
Even if you're a decade or two shy of the big 5-0, chances are your feet have seen more than their fair share of abuse — especially if you wear high heels on a regular basis.
New research conducted at UAB may stave off the emergence of treatment-resistant gonorrhea and add another weapon to the arsenal for treating the sexually-transmitted infection.
Heaton will help oversee the scientific peer-reviewed journal Workplace Health and Safety: Promoting Environments Conducive to Well-Being and Productivity.
Abou-Arraj’s fellowship will involve developing a novel technology of a targeted delivery of growth factors to dental implant and root surfaces.
The LIBERATE Study will further investigate the Eclipse System, the first vaginal insert designed to provide bowel control.
Hundreds of students will present academic pursuits in cutting-edge research topics.
UAB offers two national clinical trials with customized treatment for lung cancer patients.
Best of 2015 2The intensive intervention was four hours a day, five days a week, for a total of 200 hours of face-to-face instruction, and neuroimaging revealed brain connectivity changes.
An experimental drug that mimics a hunger-signalling hormone can protect memory in mice with Alzheimer’s disease, scientists have found.
David Becker, a health economist at the University of Alabama at Birmingham, said Medicare data can help spot possible fraud by comparing payments among different health care providers.
Last year, alprazolam was found in 29 percent of DUI cases, compared to 23 percent for marijuana. The percentage of DUI cases caused by alprazolam has held steady for the past three years, according to the data.
More than 123,300 heel-related injuries were treated in emergency rooms in the United States from 2002 to 2012, with the rate doubling during that 10-year span, according to a recent study published in the Journal of Foot and Ankle Injuries by researchers at the University of Alabama at Birmingham.
A series of fascinating studies showed that many people respond positively to placebo pills — even when they are told that the pills don't have any active ingredients. Researchers are now testing these "open-label" placebos for the first time among cancer survivors.
Researchers at the University of Alabama at Birmingham found that long-term administration of a drug that is similar to the hormone ghrelin protected Alzheimer’s disease-model mice from memory deterioration, despite a high-glycemic-index (GI) diet.
Parent-teen contracts are a useful way to set rules about what is allowed/not allowed with regard to driving.
One of the hottest issues in State Houses this year was Common Core, national math and language arts standards released in 2010 and adopted by most states.
Researchers at the University of Alabama at Birmingham found that long-term administration of a drug that mimics the hormone ghrelin protected Alzheimer's disease-model mice from memory deterioration, despite a high-glycemic-index (GI) diet.
More than 30,000 Americans commit suicide each year, and a new grant awarded to the Department of Psychiatry at the University of Alabama at Birmingham is funding a study to find out what pushes someone to take their own life.
The current method of diagnosing bacterial meningitis isn't always accurate and rarely comfortable for the patient, said Scott Barnum, professor within UAB's Department of Micobiology and lead researcher for the project.
Nolen’s song “Mend the Heart of Dixieland” was selected to win, while Clinton Babers II and his song “Here in Alabama” were chosen as second-place finalist and best live performance.
Macrophage cells require agility to scavenge and digest dead cells and prevent an immune response to self. In lupus, the macrophages lose that agility.
A series of fascinating studies at Harvard University showed that many people respond positively to placebo pills — even when they are told that the pills don't have any active ingredients. Now researchers at UAB have partnered with a Harvard scientist to test these "open-label" placebos for the first time in cancer survivors.
Photographs made in and about the South by students in the Department of Art and Art History will be on exhibition at the Shelby County Arts Council Gallery.
Only 14.3 percent of men and 29.9 percent of women reported that they regularly use sunscreen on both their face and other exposed skin.
There seems to be a genetic predisposition for psoriasis in some people. Along the way, something triggers the predisposition. It can be an illness, a medication, drinking alcohol or smoking. Smoking particularly seems to be associated with greater difficulty in clearing psoriasis lesions. Stress seems to trigger flares.
UAB’s David Pollock, Ph.D., recently visited Cuba with a delegation from the American Physiological Society to sign a historic agreement for research collaboration with Cuban counterparts.
Boni Elewski, M.D., and Wendy Cantrell, DNP, pursue research and therapies that bring new drugs to market and change patients’ lives.
Deadlines for abstracts are set for early fall and are open to graduate students, postdoctoral fellows, clinical fellows and residents.
Join a UAB team or create a team for the annual walk, which helps raise funds for research efforts.
Cardiologist Kevin Sublett will oversee the nationally accredited UAB Heart and Vascular Clinic of Central Alabama.
This improvement in cognition persists despite a high-glycemic-index diet, a possible risk factor for Alzheimer’s.
A national expert in the biomedical engineering field will chair UAB’s joint department beginning Oct. 1.
"Severe acute exacerbations of IPF are medically untreatable and often fatal within days," said Steve Duncan, M.D., professor in the University of Alabama at Birmingham Division of Pulmonary, Allergy and Critical Care Medicine.
Should your self-driving car be programmed to kill you in order to save others? Matt Windsor asked Ameen Bargh, a bioethicist at University of Alabama at Birmingham, this soon-to-be-real-life version of the classic Trolley Question.
A levodopa/carbidopa gel (Duopa) that gets delivered directly to the gut diminished non-motor symptoms in Parkinson's disease.
"With Aura, the building becomes an extension of the mobile phone's processor and memory," explained Ragib Hasan, Ph.D., assistant professor in the UAB College of Arts and Sciences Department of Computer and Information Sciences, and director of the SECRETLab research group.
UAB researchers are leading a study of the safety of the ring in adolescents. The Food and Drug Administration requires the testing of treatments in special populations, including post-menopausal women and teenagers, before approval.
Three-year grant establishes consortium to better organize and support collaborative research related to the loss of functional beta cell mass in type 1 diabetes.
The Tree Campus USA designation honors colleges and universities for promoting healthy trees and getting staff and students involved in conservation projects.
One might guess that such injuries would happen most often at a party, or, say, walking down a cobblestone street. But as Mashable reports, the study reveals that almost half of high heel injuries happen inside the home.
Brooks C. Wingo, PhD, an assistant professor of occupational therapy at the University of Alabama at Birmingham, and colleagues found standard assessments tend to underestimate the effect of obesity on children and adolescents with mobility limitations.
Celebrate all things Alabama in the second-annual LOCAL event. Peruse goods from food, art and other vendors, then enjoy live music.
A novel one-way valve blocks airflow to diseased regions of the lung, allowing healthy regions to expand and function more efficiently.
A computer science researcher at the University of Alabama at Birmingham has devised an architecture, called Aura, that would let people harness all the unused computer cycles generated by their smart home devices.
The self-driving cars that could soon dominate our roads, perhaps even making human-driven ones illegal some day, could end up being programmed to kill you if it means saving a larger number of lives.
Back to Top